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Brittle spoon shaped fingernails |
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fibrous blood clot formed in vessel that remains attached ti it's site of origin |
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an increased number of leukocytes in blood |
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unusually large stem cells in bone marrow |
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red blood cells in various sizes |
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Definition
decreased leukocytes in blood |
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red blood cells in various shapes |
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insufficient oxygenation of arterial blood |
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air, detached blood clot, or foreign body that travels in the blood stream and gets stuck in the blood stream |
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broken down red blood cells |
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Term
macrocytic-normochromic anemia |
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Definition
Large, abnormally shaped RBC with normal hemoglobin concentrations. Pernicious anemia, folate deficiency anemia |
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Term
microcytic-hypochromic anemia |
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Definition
Small, abnormal shaped RBC, reduced hemoglobin concentration Iron deficiency anemia, Sideroblastic anemia, Thallessemia |
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Normocytic-normochromic anemia |
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Definition
normal sized, normal hemoglobin concentration. aplastic anemia, posthermorrhagic anemia, hemolytic anemia, Sickle Cell, anemia of chronic disease. |
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Definition
congenital or acquired, lack of B12 for erythropoiesis. Tongue - sore, smooth, beefy red |
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Dietary folate deficiency, premature cell death d/t lack of folate for erythropoiesis. Stomatitis, dysphagia, flatulence, watery diarrhea |
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Definition
chronic blood loss, dietary iron deficiency, disruption of iron metabolism. brittle, thin, spoon shaped nails, beefy tongue |
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Definition
congenital dysfunction of iron metabolism in erythroblast, can be acquired with use of drugs or toxins. s/s bronze skin, enlargement of liver and spleen, heart rhythm disruptions,CHF |
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Term
Primary polycythemia (vera) |
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Definition
blood disorder in which the bone marrow makes too many red blood cells, enlarged spleen, plethora (ruddy red hands and face, aquagenix pruritus (extreme itching upon exposure to water) |
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Definition
caused by acute or chronic hemorrhage that stimulates increased erythropoiesis, eventual depletes body iron |
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caused by lysis or premature distruction or mature RBC in circulation d/t increased fragility of RBCs. |
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Definition
reduction of the total number of erythrocytes in circulating blood or a decrease in quality or quantity of hemoglobin. |
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Impaired erythrocyte production, blood loss, increased erythrocyte destruction |
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caused by inflammation, surgery, burns, strep, staph, exercise, DM, heparin, steroids |
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Definition
caused by decrease bone marrow production;radiation, chemo, aplastic anemia, autoimmune disease, hep B, Rubella, malaria |
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Caused by allergy, infection, malignancy, dermatosis, drugs. ex Asthma, hay fever, parasites, heparin, pcn. |
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caused by a stress response or drugs. Ex trauma, burns, mental distress, steroids |
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Caused by inflammation, hematologic disorders, and endocrine responses - chicken pox, Hodgkin's lymphoma |
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caused by physiologic response, or endocrine problems - pregnancy, ovulation, stress, graves disease |
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caused by infection, hematologic disorders- bacterial endocarditis, TB, normal newborn |
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Definition
decreased number of circulating monocytes, very rare- hairy cell leukemia and prednisone therapy. |
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Definition
caused by physiologic process, acute or chronic inflammation, endocrine problems, malignancy - Mono, syphilis, adrenal insufficiency |
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caused by immunodeficiency syndrome - AIDS, radiation, chemo, renal failure, Hodgkin's lymphoma |
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Hemolytic disease of the newborn |
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Definition
occurs when antigens in fetal blood differed from antigens in maternal blood. fetal anemia, hydrops fetalis |
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Term
Glucose-6-phosphate dehydrogenase deficiency |
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Definition
x-linked recessive disorder, present in homozygous males. abscence in G6PD allows oxidative stressors to damage hemoglobin and the plasma membrane of RBCs. |
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