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Definition
Muscle that is connected to at least two bones |
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Cords of elastic connective tissue that connect muscle to bone |
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What are the four main functions of muscles? |
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Definition
1. Produce movement 2. Maintain posture 3. Stabilize joints 4. Generate heat |
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Definition
Numerous bundles of individual muscle cells. |
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The plasma membrane of a muscle fiber |
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Rod-like structures found in the sarcoplasm of a muscle fiber which contain the fiber's contractile machinery. |
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What proteins make up the filaments in a myofibril? |
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Definition
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Definition
A saclike membranous network that surrounds each myofibril. Stores calcium. |
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Transverse Tubules (T-Tubules) |
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Definition
Structures that transmit action potentials from the sarcolemma into the cell's interior, triggering the release of calcium from the sarcoplasmic reticulum. |
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Term
Lateral Sacs (Terminal Cisternae) |
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Definition
Located near the t-tubules and store caclium |
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Term
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Definition
A t-tubule and the two lateral sacs it is associated with. |
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Definition
Protein fibers in the myofibril |
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Definition
Fundamental repeating unit that creates a myofibril |
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Definition
Border the sarcomere on either side and run perpendicular to the long axis. They also anchor the thin filaments at one end |
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Definition
Run perpendicular to the long axis and connect the thick filaments. |
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Definition
Thick filaments of the sarcomere |
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Definition
A light region in the center of the A bands in which only thick filaments are present. |
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Definition
Light region in which only the thin filaments are present. |
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Definition
Compose the thick and thin filaments of the sarcomere. Referred to as contractile proteins. |
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Term
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Definition
Actin monomers that are the basic components of each thin filament. Contains a myosin binding site. |
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Definition
Polymer made up of G actins that are bound together. Makes up actin strands found in thin filaments. |
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Definition
Protein that enable muscle fibers to start or stop contracting. |
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What are the two regulatory proteins present in thin filaments of the sarcomere? |
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Definition
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Definition
Long fibrous molecule that extends and blocks the myosin binding sites in muscles at rest. |
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Definition
Complex of three proteins that are responsible for the actions produced by calcium ions which bind to it and trigger muscle contraction. |
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Thick filaments are composed of what type of molecule? |
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Definition
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Term
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Definition
The heads of myosin molecules that bridge the gap between thick and thin filaments |
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Definition
The middle of the thick filament in which no crossbridges are present. |
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Term
What two sites do myosin heads possess? |
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Definition
Actin-binding site that can bind to actin molecules and ATPase site that controls enzymatic activity and hydrolyzes ATP. |
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During muscle contractions what happens to each region of the sarcomere? |
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Definition
The A band doesn't change. I band and H zone shorten. Z lines move closer to each other. |
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Term
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Definition
Muscles contract because the thick and thin filaments of the myofibril slide past one another. |
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Definition
The mechanism that drives the sliding of thick and thin filaments past one another during muscle contraction. |
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Term
Excitation-Contraction Coupling |
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Definition
The sequence of events that links the action potential to the contraction |
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Term
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Definition
Receive end-plate potentials, resulting in depolarization |
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Term
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Definition
A compound that donates its phosphate to ADP to form ATP which muscles rely on for immediate use during contraction. (Use while preparing to use the energy produced by oxidative phosphorylation) |
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Creatine phosphate + ADP in the presence of creatine kinase yields... |
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Definition
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Creatine is broken down into... |
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Definition
Creatinine which is excreted from the body in the urine |
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Creatinine can be measured in what bodily fluids? |
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Definition
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Creatinine measurements are performed in order to evaluate what? |
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Definition
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Term
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Definition
0.7-1.3 mg/dL for men and 06.-1.1 mg/dL for women |
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Term
Increased levels of creatinine can result from what? |
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Definition
Dehydration, renal failure, tubular necrosis, glomerulonephritis, diabetic nephropathy and rhabdomyolysis |
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Term
Decreased levels of Creatinine can result from what? |
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Definition
Muscular dystrophy and myasthenia gravis |
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Term
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Definition
Normal values 10-120 micrograms per liter. An increase in serum indicates injury or stress to muscle tissue, the hear or the brain. |
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Term
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Definition
Lacks striations Is under involuntary control by the autonomic nervous system Contains actin and myosin Does not contain sarcomeres |
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Are actin and myosin larger in skeletal muscle or smooth muscle? |
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Definition
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