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Exam 3
Equine Neuro Dz Pt 5
30
Veterinary Medicine
Professional
04/10/2017

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Cards

Term
Describe the grading system of head shaking.
Definition
-1-5
-1 = ridable, intermittent & mild signs
-5 = unrideable, uncontrollable, bizarre behavior
Term
What is the mean age of onset of head shaking?
Definition
-7-9y
-TB & geldings overrepresented
Term
What is the seasonality of head shaking?
Definition
-spring & early summer
Term
Describe the pathogenesis of head shaking.
Definition
-2 etiologies most ocmmony considered: photophobia, trigeminal neuralgia
-photic head shaking: optic=-trigeminal summation
-degen disorder of brainstem nucleus of trigeminal n
-trigeminal n is hypersensitive
Term
How do we diagnose head shaking?
Definition
-complete PE
-endoscope
-rads
-
Term
You should suspect head shaking if 2 of 3 of which signs are present?
Definition
=vertical head tossing
-acting like bug flew up nostril
-rubbing nose
Term
How do we treat head shaking?
Definition
-protect from light if photic
-cyproheptadine: anti-histamine, serotonin antagonist
-may have to add carbamazepine: Na ch blocking anti=epileptic drug
-nose nets
Term
What causes equine motor neuron dz? Physiology?
Definition
-dietary deficiency of bit E
=affects motor neurons in ventral horn & brainstem
Term
Which animals are most commonly affected by equine motor neuron dz?
Definition
-mean age of 9y
Term
What are the two forms of equine motor neuron dz?
Definition
-subacute form
-chronic form
Term
Describe the subacute form of equine motor neuron dz?
Definition
-trembling, muscle fasciculations
-base-narrow stance
-shifting wt in rear limbs
-abnormal sweating
-em atrophy
-wt loss w/ ravenous ppetite
-low head carriage
-m wasting in quads, triceps, & gluteals
Term
Describe the chronic form of equine motor neuron dz.
Definition
-poor performance
-gait abnormalities like stringhalt
-failure to gain wt
-m atrophy mild to severe
Term
What leads to chronic vit E deficiency?
Definition
-no access to quality forage or green grass for long time
Term
Describe the pathophys behind equine motor neuron dz.
Definition
-denervation m atrophy
-free radical damage
Term
How do we diagnose equin emotor neuron dz?
Definition
-biopsy of sacrocaudalis dorsalis m
Term
What are some major differentials for equine motor neuron dz?
Definition
-laminitis
-rhabdomyolysis
-colic
-botulism
-EPM
-PSSM
Term
HOw do we treat equine motor neuron dz?
Definition
-none effective
-acutely: steroids, DMSO, vit E
-full recovery unlikely b/c neuronal death is permanent
Term
HOw do we prevent equine motor neuron dz?
Definition
-supplement vit E if horses have no access to high quality hay or grass
Term
What is the prognosis of equine motor neuron dz?
Definition
-poor for return to performance
-gaurded for life
Term
What are the other nambes for hypoxic ischemic encephalopathy?
Definition
-neonatal maladjustment syndrome
-dummy foals
Term
What causes hypoxic ischemic encephalopathy?
Definition
-hypoxia due to complicated pregnancy or labor
Term
How common is hypoxic ischemic encephalopathy?
Definition
-2nd most common cause of death in neonates after sepsis
Term
What is the basic mechanism of asphyxia due to hypoxic ischemic encephalopathy?
Definition
-insufficient oxygen to fetal/neonatal CNS resulting in hemorrhage, edema, and necrosis
Term
Which fetal reflexes dec due to hypoxia?
Definition
-fetal HR fails to inc w/ stimulus
-fetal breathing slows
-genealized fetal movements dec
-fetal tone dec
Term
What occurs when a hypoxic ischemic encephalopathy foal is born?
Definition
-immediate resuscitation may be necessary
-FOAL MAY BE NORMAL FOR FIRST 72H
-owner w/ notice that it nurses everything except dam & has milk face
Term
What are the CS of hypoxic ischemic encephalopathy?
Definition
-suckle reflex first to go & last to return
-barker foal
-disorientation
-blindness
-sizures
-hypotonia, coma, death
Term
How do we treat hypoxic ischemic encephalopathy?
Definition
-try to maintain tissue perfusion & O2 delivery
-fluids
-pressors to maintain BP
-free radical scavengers: DMSO
-thiamine
-Mg
-abx; most are FPT & septic
-seizure control
Term
What are some important points to remember w/ hypoxic ischemic encephalopathy?
Definition
-other organ systems are also affected: GI & kidneys
-see electrolyte derangements
-frequent episodes of hypoxia occur thus need IN O2 +/- resp stimlation (caffeine)
Term
What is the prognosis of hypoxic ischemic encephalopathy?
Definition
-good to excellent if conditions is tx early & foal is term
-dec w/ delayed or insufficient tx & concurrent problems (premature or septic)
Term
What are the high points of temperohyoid osteoarthropathy?
Definition
-can look like vestibular dz
-can have rapid clinicla onset
-can be dx via endoscopy of GP
tx = seratohyoidectomy
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