Term
When do horses get EIPH? What is EIPH? |
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Definition
-after strenuous work -Exercise-Induced Pulmonary Hemorrhage |
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Term
What is the physiology behind EIPH? |
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Definition
-capillary stress failure (capillary P + negative airway P) in the caudodorsal lung -locomotion theory: wt of colon adds to P |
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Term
What are the different grades of EIPH? |
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Definition
-1: blood flecks in trachea -2: flecks & discontinuous stream -3: continuous stream < half trachea width -4: continuous stream > half trachea width -5: airways covered w/ blood |
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Term
How does Furosemide affect EIPH? |
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Definition
-typically educes it by 1 grade |
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Term
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Definition
-endoscopy w/in an hr of exercise -BAL w/in an hr post-exercise -TTW/BA: w/in 21d for hemosiderophages |
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Term
What do we see on rads w/ EIPH? |
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Definition
-caudodorsal interstitial pattern |
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Term
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Definition
-furosemide: dec pulmonary P -Flair nasal strips -URT resistance: LLH, DDSP, pharyngitis, pharyngeal collapse |
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Term
Which horses get RAO? Etiology? |
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Definition
-adults: worsens w/ age -inhaled allergens |
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Term
What effects does RAO have on the body? |
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Definition
-bronchoconstriction -inflammatory cells: neutrophils -mucus pdc inc + plugging -airway SM becomes hypertrophied -hypoxemia can result in severe cases |
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Term
What is the typical RAO history? |
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Definition
-cough at onset of exercise -chronic cough -intermittent low grade mucoid secretions -exercise intolerance -dyspnea |
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Term
What are the clinical signs of RAO? |
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Definition
-severe dyspnea -wt loss -nostril flare -audible wheezing -heave line -hypoxemic |
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Term
What do we hear on auscultation of RAO? |
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Definition
-inc expiratory effort -expiratory wheezes -cough induced on rebreathing bag exam -poor recovery after exercise |
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Term
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Definition
-hx + CS + auscultation -TTW/BAL > 20% neutrophils -endoscopy: mucus -R/O concurrent infection |
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Term
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Definition
-aggressive tx in crisis -pre-exercise inhalers -change environment!! |
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Term
For crisis treatment, what drugs do we give RAO cases? |
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Definition
-Bronchodilator: Clenbuterol -Corticosteroids: Dex, Pred -Inhalants: Albutrol, fluticasone, beclomethasone |
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Term
What is our major concern w/ long-term tx of RAO w/ Clenbuterol? |
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Definition
-down regulation of bea rc -affects cardiac function & aerobic performance |
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Term
What are our RAO management methods? |
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Definition
-change environment -minimize dust -HIGH QUALITY WET HAY -can also feed on ground or use pelleted rations -NO ROUND BALES |
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Term
Who gets Inflammatory Airway Dz? |
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Definition
-young racehorses & other young performance horses |
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Term
What are the clinical signs of Inflammatory Airway Dz? |
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Definition
-chronic coughing -nasal discharge -mucopurulent exudate in pharynx, trachea, and bronchi -chest ausculation usually normal -exercise intolerance |
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Term
What do we see on BAL w/ Inflammatory Airway Dz? |
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Definition
-inc total cell count w/ mixed inflammation |
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Term
How do we treat Inflammatoyr Airway Dz? |
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Definition
interferon-alpha -corticosteroids: Dex, Pred -inhalants not available anymore |
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Term
How do we handle eosinophilic inflammation in resp system of the horse? Any etiologic ideas? |
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Definition
-corticosteroids -consider Dictyocaulus arnfeldi (lungworm from donkeys) |
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Term
How do we handle mast cell inflammation in resp system of the horse? |
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Definition
-nebulization of sodium cromoglycate daily |
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