Term
| What is the most common acquired secondary hemostasis disorder? |
|
Definition
| -anticoagulant rodenticide toxicity |
|
|
Term
| What is the treatment of choice for anticoagulant rodenticide toxicity? |
|
Definition
| -vitamin K with plamsa and RBC transfusion |
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|
Term
| What is the difference b/n fresh frozen and frozen plasma in one word? |
|
Definition
|
|
Term
| What is the most common indication for plasma? |
|
Definition
| -coagulopathy (secondary hemostasis) |
|
|
Term
| What two instances use platelet trasnfusions? |
|
Definition
| -life-threatening hemorrhage associated with severe thrombocytopenia AND in preparation for surgery in patients with severe thrombocytopenia |
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|
Term
| What are the components of the leukogram? |
|
Definition
-neutrophils: segmented and bands
-lymphocytes
-monocytes
-eosinophils |
|
|
Term
| Do we use absolute numbers or percentages to inerprate leukocyte type on a leukogram? |
|
Definition
|
|
Term
| What can cause neutrophilia? Describe it in each case. |
|
Definition
-stress: mature neutrophilia nor more than 2X upper limit
-inflammation: infection, neoplasia, immune-mediated disease, non-infectious inflammatory |
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|
Term
| What are some causes of neutropenia? |
|
Definition
-dec production
-consuming => being "dumped" somewhere
-immune-mediated destruction |
|
|
Term
| What are the 3 tope differentials for band neutrophils? |
|
Definition
-infection
-moderate to severe systemic inflammation: IMHA, acute necrotizing pancreatitis
-bone marrow "reboud" |
|
|
Term
| What causes toxic change to neutrophills? |
|
Definition
-typically indicates infection
-can see with SEVERE non-infectious inflammatory conditions: IMHA, necrotizing pancreatitis |
|
|
Term
|
Definition
| -inflammation (non-specific): infection, neoplasia, immune-mediated, non-infectious inflammatory |
|
|
Term
| What are the 6 most common causes of ly6mphocytosis? |
|
Definition
-YOUNG and recent vaccination (antigenic stimulation)
-stress: CATS ONLY
-ehrlichiosis
-leukemia
-lymphoma with bone marrow involvement
-HYpoadrenocorticism (Addison's disease) |
|
|
Term
| What commonly causes lymphopdenia in dogs? |
|
Definition
|
|
Term
| What are the major two causes of eosinophilia? Other possible causes? |
|
Definition
-parasites & allergy
-other: addison's dz, neoplasia, infection, hypereosinophilic disorders |
|
|
Term
| What does a stress leukogram look like? |
|
Definition
-mature neutrophilia under 2X normal
-lymphopenia
-monocytosis
-eosinopenia |
|
|
Term
| What are the potential causes of increased nRBCs? |
|
Definition
-earrly release from bone marrow: have strongly regen anemia (could be marrow injury like heat stroke orneoplasia)
-ixtramedullary hematopoiesis
-splenectomy or splenic dysfunction/disease
-lead toxicity
-erythroid neoplasia |
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