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Exam 3
Muscles, Nervous, CNS
24
Anatomy
Undergraduate 2
04/07/2015

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Cards

Term
Z line (disc)
Definition
anchor for thin filaments
Term
M line
Definition
anchor for thick filaments
Term
A band
Definition
dark area; extends length of the thick filaments
Term
I band
Definition
light area; thin myofilaments only (Z disc is center)
Term
H zone
Definition
thick myfilaments only (M line is center)
Term
Sarcomere
Definition
functional unit of skeletal muscle; Z disc to Z disc; aligned end to end within myofibril
Term
Myosin
Definition
Makes up thick filaments; has rodlike tail and two globular heads which contain binding sites for actin and ATP
Term
Actin
Definition
Makes up thin filaments; made of G-actin
Term
G-actin
Definition
Contain binding sites for myosin heads
Term
Tropomyosin
Definition
In thin filaments; rod-shaped protein that runs along actin; blocks myosin-binding sites on actin when muscle is relaxed
Term
Troponin
Definition

In thin filaments; 3 polypeptide subunit complex

-1 subunit bound to actin

-1 subunit bound to tropomyosin

-1 subunit binds Ca2+

Term
Sarcoplasmic Reticulum
Definition
Stores and regulates intracellular Ca2+
Term
Terminal cisternae
Definition
perpendicular tubes of the sarcoplasmic reticulum
Term
T Tubules
Definition
invaginations of sarcolemma; "transverse" tubules
Term
Axon Terminal
Definition
End of neuron
Term
Synaptic vesicle
Definition
part of the axon terminal that contains acetylcholine (ACh)
Term
Synaptic Cleft
Definition
space between axon terminal and sarcolemma
Term
Motor End Plate
Definition
specialized area of muscle fiber that synapses with axon terminal
Term
Junctional folds
Definition
component of motor end plate that has ACh receptors
Term
Voltage gated channel
Definition
opens when membrane potential changes
Term
chemically (ligand) gated channel
Definition
opens when a chemical binds
Term
Mechanically gates channel
Definition
open in response to mechanial movement
Term
Depolarization
Definition
membrane potential becomes less negative
Term
end plate potential
Definition
initial depolarization of motor end plate
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