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Exam 3
Genetics
93
Biology
Undergraduate 1
11/11/2014

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Term
How does DNA carry genetic information?
Definition
Stored in the sequence of bases along a nucleic acid. A chromosome which carries the genetic info in the form of DNA is found inside the DNA.
Term
What is a genome?
Definition
The haploid set of chromosomes in a gamete or microorganism.
Term
A segment of DNA found on a chromosome is called a____?
Definition
Gene
Term
How many phases are there in mitoses.
Definition
4
Term
Name the phases of mitosis in order from the beginning to the end of cell divison
Definition
Prophase, Metaphase, Anaphase, Telophase/Cytoinesis
Term
The period of growth during the cell cycle is called____?
Definition
G1 phase
Term
What are autosomes?
Definition
Any cell that is not a sex cell
Term
What are somatic cells?
Definition
Sex cells
Term
How many daughter cells are produced at the end of mitosis?
Definition
2
Term
What is cytokineses?
Definition
Division of cytoplasm
Term
During which phase of the cell cycle are DNA and centrioles of animal cells replicated?
Definition
Interphase
Term
What are thin, tangled strands of DNA called that are present during interphase?
Definition
Chromatin
Term
During which phase of mitosis do the chromosomes line up in the middle of the cell?
Definition
Metaphase
Term
During which part of mitosis do the chromosomes first become visible?
Definition
Prophase
Term
During which part of mitosis do the centrioles begin to move to opposite poles?
Definition
Prophase
Term
During which part of mitosis do the nucleolus and nuclear membrane disappear?
Definition
Prophase
Term
During which phase of mitosis do the spindle fibers begin to form?
Definition
Prophase
Term
What structure attaches the chromosome to the spindle fibers during metaphase?
Definition
Centromere
Term
A cell with a full set of chromosomes is said to be?
Definition
Diploid
Term
What is one half of a chromosome called?
Definition
Chromatid
Term
During which phase of mitosis are the sister chromatids pulled apart?
Definition
Anaphase
Term
What are sister chromatids?
Definition
Identical halves that make a chromosome
Term
During which phase of mitosis do the spindle fibers begin to shorten?
Definition
Anaphase
Term
What cell parts reappear during telophase?
Definition
Cell membrane and nucleous.
Term
What is meiosis?
Definition
Production of sex cells
Term
What are the functions of meiosis?
Definition
Aid and perform reproduction
Term
Mitosis
Definition
Repair, grow, maitenence, Divides DNA, Autosomes, cells have 46 chromosomes, PMAT.
Term
Meiosis
Definition
Produce sex cells, aid and perform reproduction, Meiosis 1 and 2, Gametes/Somatic cells, 23 chromosomes.
Term
Crossing Over
Definition
2 chromosomes pair up and exchange segments of genetic material
Term
In which phase of Meiosis does crossing over occur?
Definition
Meiosis 1.
Term
Independent Assortment
Definition
When genes seperate on their own
Term
In which phase of Meiosis does independent assortment occur?
Definition
Meiosis 1
Term
What types of organisms undergo Meiosis?
Definition
Animals
Term
What is the advantage of sex?
Definition
Introduces new combos of heritable traits in the offspring, large and multicellular organisms that have limited #'s of offspring & evolve slowly, Must keep up with rapid evolution of parasites, bacteria, and viruses
Term
How is sex determined in humans?
Definition
Father sperm
Term
Genotype
Definition
Genetic Makeup
Term
Phenotype
Definition
Physical appearance
Term
Homozygous
Definition
Same alleles
Term
Heterozygous
Definition
Two different alleles
Term
Parental Generation
Definition
The parents the mate
Term
F1 generation
Definition
The parents offspring
Term
F2 generation
Definition
The offsprings offspring
Term
Dominant
Definition
The overpowering gene
Term
Recessive
Definition
The less likely gene
Term
Test Cross
Definition
Breeding
Term
Haploid
Definition
23 chromosomes
Term
Diploid
Definition
46 chromosomes
Term
Complete Dominance
Definition
1 is more dominant than the other
Term
Co-Dominace
Definition
Both alleles are equally dominant
Term
Incomplete dominance
Definition
Blending
Term
Multiple Alleles
Definition
More than 2 genes
Term
Monohybrid
Definition
Mating between individuals who have same alleles at one genetic locus of interest (true breeding)
Term
Dihybrid cross
Definition
Heterozygous cross
Term
Independent Assortment
Definition
2 or more genes assort independently.
Term
Law of Independent Assortment
Definition
2 or more genes will assort independently
Term
Law of Segregation
Definition
During gamete production the 2 copies of each hereditary factor segregate so that the offspring acquire one factor from each parent
Term
Addition Law
Definition
Probabilty that any 1 of 2 or more mutually exclusive events will occur is calculated by adding individual probabilities
Term
Multiplication Law
Definition
Multiply probability of 1 event by the probability of another
Term
DNA
Definition
Can replicate, make copies, serves as a pattern for duplication of bases
Term
Topoisomerase
Definition
Breaks, swivels, and rejoins the parental DNA ahead of the replication fork, relieving the strain caused by unwinding
Term
Helicase
Definition
Enzymes that untwist the double helix at the replication forks, separating the two parent strands and making them available as template strands.
Term
Single strand binding proteins
Definition
Stabilize the unwound parental strands
Term
anti-Parallel
Definition
Sub-units run parallel but in opposite directions
Term
Leading Strand
Definition
Continous in the 5'-3' direction toward the fork
Term
Lagging Strand
Definition
Multiple sites of initiation are exposed
Term
Okaski Fragment
Definition
Short segments of lagging strand
Term
Primase
Definition
Synthesizes RNA primers, using the parental DNA as a template
Term
Primer
Definition
DNA chain
Term
Transcription
Definition
Process of making an RNA copy of a gene sequence called messenger RNA
Term
Translation
Definition
Translated mRNA molecules to a sequence of amino acids during protein synthesis.
Term
Telomere
Definition
Region of repetitive nucleotide sequences at the end of a chromatid, which protect the end of chromosomes from deterioration
Term
Origin of Replication
Definition
Sequence of DNA at which replication is initiated on a chromosome.
Term
B-DNA
Definition
Most common form of DNA in living organisms in which the double helix twists in right-hand direction
Term
Centromere
Definition
Inside the sister chromatins in the middle where they come together, mostly non-coding DNA
Term
Semi-Conservative replication
Definition
The parents come together again to produce two daughter cells with new and old strands of DNA
Term
How is DNA replicated?
Definition
The double helix is unwound and each strand acts as a template for the next strand. Bases are synthesized to match the new partner strand
Term
How are bases paired up?
Definition
Each base is attached to a sugar held together by a hydrogen bond. C-G A-T
Term
How many hydrogen bonds are found at each base pair?
Definition
C-G=3 A-T=2
Term
What chemical bonds exist in a DNA molecule
Definition
Hydrogen and Covalent bonds
Term
What does 5' and 3' mean?
Definition
Indicates the carbon numbers in the DNA sugars backbone.
Term
Why is DNA copied into the 5' to 3' direction?
Definition
Guides the DNA strands in one direction for replication.
Term
What is noncoding DNA and it's biological importance?
Definition
DNA that doesnt code for anything (Junk DNA)
Transcription and translation regualation of protein coding sequences.
Term
What is the difference between primary mRNA and mature mRNA
Definition
Primary mRNA is when the transcript is about to be spliced and mature mRNA is when the transcript has already been spliced
Term
What word refers to a part of mRNA that must be removed before mature mRNA is produced?
Definition
Introns
Term
What is the function of mRNA?
Definition
Carries codes from the DNA in nucleous to the sites of protein synthesis in the cytoplasm
Term
What is the function of ribosomal RNA?
Definition
Catalyze the assembly of amino acids in protein chains.
Term
What is a codon?
Definition
Sequence of 3 nucleotides that together form a unit of genetic code in a DNA or RNA molecule.
Term
What is transcription?
Definition
Transcribes genetic info from DNA to RNA.
Term
Describe transcription.
Definition
RNA polymerase binds to DNA, DNA is transcribed by RNA polymerase which attaches to DNA at promoter region, then elongation occurs.
Term
Translation
Definition
Proteins are synthesized from the info in mRNA.
Term
Describe transaltion
Definition
Initiation, elongation, termination
Term
Genetic Code
Definition
Set of rules by which info encoded in genetic material is translated into proteins by living cells.
Term
tRNA
Definition
Helps decode the messenger RNA sequences into proteins.
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