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Exam 3
Male, Female, Endo, Eye
64
Histology
Professional
04/21/2014

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Term
spermatocytogenesis
Definition
production of spermatocytes (1* and 2*) from spermatogonia
Term
spermiogenesis
Definition
morphological differentiation to spermatozoa from spermatocytes
Term
Golgi phase of spermiogenesis
Definition
Golgi gives rise to acrosome and migrates to one side of cell and centrioles to opposite side
Term
acrosomal phase of spermiogenesis
Definition
acrosomal cap flattends and spreads over surface of nucleus
rotation so centriles and growing flagella face lumen of seminiferous tubule
axoneme outgrowth begins
Term
maturation phase o spermiogenesis
Definition
redisdula body shed, sperm released into lumen
phase continues until reaching epididymus where they gain ability to fertilize an egg
Term
rete testis
Definition
elaborate network of channels near mediastinum of testis
squamous, cuboidal, columnar cells
dense fibromuscular stroma
Term
efferent ductule
Definition
segment that leaves the testis and goes to epididymus
ciliated pseudostratified epithelium with short cells (absorptive)
only ciliated cells in male tract
cross mediastinum testis and tunica albuginea
Term
ductus epididymus
Definition
pseudostratified columnar epithelium with stereocilia
location of capacitation of sperm
prominent muscularis (head - 1 layer, circular; tail - 2 layers, inner circ outer long)
Term
colliculus seminalis
Definition
where ejaculatory ducts enter prostate
Term
mucosal arches
Definition
highly folded, convoluted wall of seminal vesicles; very rich vasculature and smooth muscle present
Term
corpora amylacea
Definition
eosinophilic, glycoprotein-rich concretions in lumen of glands of prostate
Term
ejaculation events
Definition
bulbourethral glands - lubrication
prostate - preps vagina
ductus deferens - perstaltic, sympathetic, propulsion
seminal vesicle - clears out urethra after
Term
supraoptic and paraventricular nuclei
Definition
located in hypothalmus
produce vasopressin and oxytocin
Term
GHRH
Definition
made by neurosecretory neurons of hypothalamus
targets somatotrophic cells of anterior pituitary
stimulates synthesis and release of GH
Term
TRH
Definition
made by neurosecretory neurons of hypothalamus
targets thyrotropic and mammotropic cells of anterior pituitary
stimulates synthesis and release of TSH and prolactin
Term
CRH
Definition
made by neurosecretory neurons of hypothalamus
targets corticotropic cells of anterior pituitary
stimulates synthesis of POMC and release of B-KPH and ACTH
Term
GRH
Definition
made by neurosecretory neurons of hypothalamus
targets gonadotropic cells of anterior pituitary
stimulates the release of FSH and LH
Term
Dopamine (PIF)
Definition
made by neurosecretory neurons of hypothalamus
targets mammotropic cells of anterior pituitary
inhibits release of prolactin
Term
Somatostain
Definition
made by neurosecretory neurons of hypothalamus
targets somatotropic and thyrotropic cells of anterior pituitary
inhibits release of GH and TSH
Term
vassopressin (ADH)
Definition
made by supraoptic and paraventricular nuclei of hypothalamus
released by posterior pituitary continuations of hypothalamic neurons
targets collecting ducts in kidney
stimulates water re-absorption
Term
oxytocin
Definition
made by supraoptic and paraventricular nuclei of hypothalamus
released by posterior pituitary continuations of hypothalamic neurons
targets myoepithelial cells (mammary glands) and smooth muscle (uterus)
stimulates contraction of target cells
Term
hypophysis
Definition
pituitary gland
Term
adenohyophysis
Definition
anterior pituitary: pars tuberalis, pars intermedia, pars distalis
derived from oral ectoderm
Term
neurohypophysis
Definition
posterior pituitary: infundibular stalk, pars nervosa
derived from diencephalon (neuroectoderm)
Term
acidophilic chormophils in pars distalis
Definition
somatotropic and mammotropic cells
Term
adrenal cortex
Definition
glomerulosa, fasciculata, and reticularis (salt, sweet, sex)(mineralocorticoids, glucocorticoids, androgens)
derived from mesoderm
Term
adrenal medulla
Definition
chromaffic cells "postganglionic neurons" catecholamines
derived from neural crest cells
Term
ovarian follicle
Definition
oocyte and follicular epithelial cells
Term
theca follicle
Definition
mesencymal derived tissue that surrounds the ovarian follicle and is a source of estrogen during follicular development
Term
primordial follicle
Definition
immature oocyte in prophase I
single layer, flattened follicular epithelial cells
Term
developing (primary) follicle
Definition
follicular cells stimulated by FSH proliferate and become cuboidal = granulosa cells
theca follicle begins to form
zona pellucida is present
oocyte increases in size, still prophase I
Term
secondary (antral, vesicular) follice
Definition
granulosa cell secrete fluid that forms lake
apoptosis of granulosa cells to make room
theca interna cells are differentiated
oocyte is at full size, still prophase I
Term
mature (Graffian) follicle
Definition
follicle is very large
tremendous amoung of fluid
corona radiata present
cumulus oophorus present
oocyte completes meiosis I (shed first polar body) and stops in metaphase II
Term
follicle regulatory protein (FRP)
Definition
released by FSH-stimualted, dominant folicle
survival of the fittest process to inhibit maturation of other follicles
Term
events of ovulation
Definition
columus oophorus breaks down
estrogen stimulates LH surge
ovarian stoma weakens
proteolytic enzymes released in stoma
granulosa cells weaken
follicle wall ruptures
oocyte with corona radiata released into peritoneal cavity
Term
Peg cells
Definition
found in mucosa of oviducts
produce and secrete substances to help sperm activation
Term
spiral (coiled arteries)
Definition
bridge endometrial basalis to funtionalis
heavily muscular, grow and shed parts with endometrial cycle
Term
proliferative uterine phase
Definition
wound-healing process
driven by estrogen
epithelial and stromal proliferation
endometrium thickens and uterine glands lengthen/coil
cells accumulate glycogen
coiled arteries regrow into functionalis
Term
secretory uterine phase
Definition
progesterone (corpus luteum) --> accumulation of secreted product in lumen of glands
endometrium continues to thicken
uterine glands become swollen, tortuous, irregular
coiled arteries elongate
Term
premenstrual uterine phase
Definition
immediately before loss of functionalis from vascular insufficiency
estrogen/progestone levels fall w/o pregnancy
prostaglandins release in CT of encometrium
coiled arteries constrict and limit blood flow
lymphocytes, macrophages invade stroma
coiled arteries close and open intermittently
ischemia --> cell lysis --> weaken stroma
vessels burst, blood debrides functionalis
Term
menstruation uterine phase
Definition
beginning of uterine cycle
funtionalis is shed
base of uterine glands retained in basalis
Term
cervical mucus
Definition
mid-cyle: estrogen stimulated, watery, fish-ladders, lysozyme
late-cycle: viscous
pregnancy: particularly dense, impenetrable, protective plug
Term
inactive mammary gland
Definition
duct elements and very primitive alveolar bud structures
Term
pregnancy mammary gland
Definition
duct elements and alveolar buds expand and elaborate
Term
lactating mammary gland
Definition
lumen of alveolar structures is filled with secretory product
Term
colostrum
Definition
first milk
lactoprotein-rich, immunoglobulin-rich, low lipid content
Term
milk let-down
Definition
suckling -> oxytocin -> contraction of myoepithelial cells -> carry milk through duct system -> afferent CNS inhibit dopamine -> prolactin release -> lactation
Term
vitreous body
Definition
oocupied by gelatinous mass, helps maintain shpae of eye
consumes the posterior cavity
Term
ora serrata
Definition
anterior-most extent of photosensitive retina
neural retina ends, but pigmented epithelium continues
Term
fibrous tunic
Definition
cornea + sclera
Term
uvea
Definition
tunica vasculosa = vascular tunic
middle wall of eye
iris, ciliary body, choroid
Term
Bowman's membrane
Definition
between epithelium and stroma of cornea
fairly thick
not typical BM
Term
Descemet's membrane
Definition
between stroma and endothelium of cornea
not typical BM
Term
corneal epithelium
Definition
stratified squamous non-keratinizing
Term
keratocytes
Definition
fibroblastic cells in the stroma of the cornea
Term
corneal endothelium
Definition
simple cuboidal
Term
aqueous humor
Definition
produced by epithelium on cliearly processes (suface epithelium)
Term
Bruch's membrane
Definition
separates choroid from retinal pigment epithelium
part of the choroid
Term
oxytalin fibers
Definition
ciliary zonules, ligaments
from BM of non-pigmented ciliary epiethlium, across posterior chamber, to BM of lens
Term
distance vision
Definition
ciliary muscle relaxes
zonules tense
lens flattens
Term
near vision
Definition
ciliary muscle contracts
zonules relax
lens bulges
Term
ciliary channel
Definition
potential space between deed and surface epithelium of the ciliary body
between the apical membranes of both epithelial layers
Term
crystallins
Definition
major protein in the lens fiber cells
increase refractive index of lens
highest in content near center of lens
Term
retina pigment epithelium
Definition
simple cuboidal
rests on Bruch's membrane of choroid
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