Term
| inhalational anesthetics-4 |
|
Definition
nitrous oxide
isoflurane
halothane
enflurane |
|
|
Term
|
Definition
procaine
tetracaine
bupivacaine
lidocaine |
|
|
Term
|
Definition
barbs
opioids
BDZs
neuroleptics |
|
|
Term
|
Definition
|
|
Term
| advantages of local anesthetics-2 |
|
Definition
reversible
minimal systemtic |
|
|
Term
| disadvantages of local anesthetics-2 |
|
Definition
require compliance
possible systemic effects |
|
|
Term
|
Definition
|
|
Term
| the Ad fibers are the thickest/thinest |
|
Definition
|
|
Term
| in normal rest state the nerve has potential of |
|
Definition
|
|
Term
| stimulation of the nerve has depolarized membrane potential of |
|
Definition
| +35 (look on slide 6 to see all the states) |
|
|
Term
the site of action for LAs is-
so what must they do?
this means potency is related to- |
|
Definition
cytoplasmic plasma membrane
cross the membrane!
lipiphillicty |
|
|
Term
the _ form is most active
the _ form is nessecary for rapid penetration of membrane |
|
Definition
|
|
Term
| the greater the _ fraction for anesthetic, the faster the onset |
|
Definition
|
|
Term
| what drugs have the more non-ionized form-2 |
|
Definition
|
|
Term
| which LAs have slow onset-2 |
|
Definition
|
|
Term
| _ in pH delays onset of action |
|
Definition
| decrease (bc gets ionized) |
|
|
Term
LAs except cocaine do not cause-
they do cause |
|
Definition
local vasoconstriciton
vasodillatory |
|
|
Term
| what is included in LA solution to cause vasoconstriciton to delay absorption and extend DOA |
|
Definition
|
|
Term
esters are metabolized to _
this can cause?
an example |
|
Definition
PABA
more allergic rxn than amides
tetracaine |
|
|
Term
|
Definition
|
|
Term
|
Definition
CNS stimulation, drowsiness
decrease cardio excitablilty
smooth muscle relaxaiton |
|
|
Term
| 2 symtpoms of LA toxicity |
|
Definition
|
|
Term
| topical anesthesia used for-2 |
|
Definition
|
|
Term
| infiltration anesthesia is for |
|
Definition
|
|
Term
| clinical uses of aneshtesi include-3 |
|
Definition
| field block, spinal, epidural |
|
|
Term
| the lipophillic protion is for- |
|
Definition
|
|
Term
| the intermediate chains are for- |
|
Definition
|
|
Term
| the hydrophillic portion is for |
|
Definition
|
|
Term
| Procaine is short acting, has a lot of allergies * |
|
Definition
|
|
Term
|
Definition
slow
topically, opthalmis, spinal bc long lasting |
|
|
Term
| which drug is effective wihtout an added vasoconstrictor |
|
Definition
|
|
Term
| Lidocaine is resistant to |
|
Definition
|
|
Term
|
Definition
medium
rapid
usefull all around |
|
|
Term
|
Definition
lidocaine
bupivacaine
mepivicaine |
|
|
Term
bupivacaine
onset:
DOA:
useful: |
|
Definition
intermediate
long
labor/post op |
|
|
Term
mepivacaine
onset
duration- |
|
Definition
|
|
Term
| which med doesnt have vasodilation |
|
Definition
|
|
Term
| whihc drug is toxic to neonates |
|
Definition
|
|
Term
| which drug can cause methemoglobinemia |
|
Definition
|
|
