Term
which drug has michaelis menton kinetics what does this mean? |
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Definition
phenytoin small dose increase= large serum increase |
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Term
which drugs are highly protein bound (can displace drugs liek coumadin) |
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Definition
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Term
therapetuic level for phenyotin |
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Definition
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Term
what is equation for corrected phenytoin |
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Definition
observed conc / (.2 x albumin +.1) |
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Term
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Definition
neurotoxic osteopenia gingival hyperplasia acne |
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Term
what are the hepatic inducers (will decrease cl of drugs thru liver) |
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Definition
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Term
what increases Cl of phenytoin |
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Definition
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Term
if phenytoin plasma conc is < _ you increase dose |
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Definition
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Term
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Definition
liver, thryoid, CBC, oral hygiene |
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Term
what drug does food increase bioavail |
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Definition
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Term
carbamezapine is metab by |
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Definition
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Term
therapeutic level for carbamezapine -when do you draw dose |
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Definition
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Term
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Definition
neurotoxic osteopenia agrnaulocytoiss (!!!) |
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Term
what drug do you disct if wbc<2500 or ANC<1000 |
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Definition
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Term
whihc drug is an autoinducer what does this mean? |
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Definition
carbamezapine conc will decrase during fisrt month |
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Term
hepatic _ increase Cl of carbamezapine |
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Definition
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Term
monitoring for Carbamezapine |
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Definition
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Term
valproic acid is also called |
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Definition
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Term
therapeutic level for valproic acid |
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Definition
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Term
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Definition
neurotxic osteopenia thrombocytopenia, PCOS |
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Term
valproate does what on hepatic what drug is the big concern when used with this? |
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Definition
inhibitor lamotrigine (will decrease clear) |
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Term
monitoring for valproic acid |
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Definition
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Term
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Definition
life threat hypersensitivity (steven johnson), CNS depression, GI |
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Term
hepatic _ increase Cl of lamotrigine |
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Definition
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Term
what drug increases risk of rash when used with lmaotrigine |
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Definition
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Term
oral contrceptives cna decrease which med |
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Definition
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Term
monitoring for lamotrigine |
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Definition
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Term
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Definition
myopia, CNS depression, kidney stones |
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Term
dont use topiramate with-3 |
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Definition
phenytoin, carbamezapine, carbonic anhydrase inhibitors |
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Term
monitoring for topiramate |
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Definition
drink fludis to prevent kid stones, eye exam |
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Term
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Definition
hypoNa and decrease cognition |
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Term
oxcarbamezapine inhibits _ induces_ |
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Definition
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Term
monitoring for oxazarbamezapine |
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Definition
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Term
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Definition
CNS depression, psychosis, anemia |
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Term
*** Keppra doesnt interact with CYPs |
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Definition
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Term
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Definition
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Term
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Definition
allergy to sulfa, hyperthermia, wt loss |
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Term
if other drugs act on _, they mess with zonisamide |
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Definition
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Term
monitoring for zonisamide |
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Definition
BUN, drink fluids to prevent kid stones |
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