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Exam 3
Lecture 4
63
Art/Design
Undergraduate 1
04/30/2013

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Term
definiton of HF based on symptoms:
Definition
dyspnea and fatigue by ABNORMAL cardiac functions
Term
definition of HF based on function
Definition
heart cannot pump efficiently to meet metabolic demands
Term
how do you differentiate btwn systolic and diastolic HF
Definition
EF < 40% = systolic HF
Term
HF with preserved EF is common for what HF?
Definition
diastolic
Term
LVH- left ventricular hypertrophy is common for what HF?
what other abnormality?
Definition
diastolic
left ventricle stiffness
Term
LVD- left ventricle dysfunction is common for what HF?
what other abnormality?
Definition
systolic
dilated cardiomyopathy
Term
what are the causes of decreased cardiac output- 7
Definition
HTN
infectious disease
CAD
MI
Drugs
volume overload
idiopathic
Term
what is the BIG compensaotry mechanism for a decreased cardiac output?
what is the other mechanism?
Definition
increased SNS
RAS system activation
Term
what does the activaiton of aldosterone do?
what does this increase?
Definition
water and sodium retention
preload
Term
SNS activation increases what directly-
it also constricts the veins and arteries, which increases afterload, and which does preload?
Definition
HR
constriciton of veins does preload
arteries- afterload
Term
what drug dilates the arteries?
whcih does venous side?
Definition
hydralazine
nitrites
Term
a major cause of death for HF patients is?
why?
Definition
sudden arrythmia
too much stimulation and cant compensate
Term
an increase in afterload decrease what?
Definition
SV- stroke volume
Term
which classificaiton system is based on symptoms? which is based on structure?
Definition
NYHA
ACC
Term
Stage for NYHA:
diagnosis of heart failure + no symtpoms
Definition
Stage 1
Term
Stage for NYHA:
diagnosis of heart failure + symptoms that have a little limitation of acitvity, no symptoms at rest
Definition
stage 2
Term
Stage for NYHA:
diagnosis of heart failure + symptoms that restrict a lot of acitvity, no symptoms at rest
Definition
stage 3
Term
Stage for NYHA:
diagnosis of heart failure + symptoms at rest
Definition
stage 4
Term
Stage for ACC/AHA:
- patient at high risk?
- what are the things that put them at high risk--5
Definition
stage A
HTN, CAD/CVD, diabetes, obesity, metabolic syndrome
Term
Stage for ACC/AHA:
- patient has strucutural heart diease but no symptoms of HF
- Examples: -3
Definition
Stage B
previous MI, left ventricle dysfunction, LVH
Term
Stage for ACC/AHA:
- patient with strucutre problem + symptoms (current or PREVIOUS)
- Ex of symptoms: -3
Definition
Stage C
dyspnea, fatgue, reduced exercise tolerance
Term
Stage for ACC/AHA:
- patient with refractory HF needing special interventions
-Ex:
Definition
Stage D
patient on max therapy but still symptoms at rest
Term
what is the first thing to do in determining treatment?
Definition
what is the cause or factors
Term
what are 3 etiologies of HF
Definition
drug adherence
medications
disease associated with HF
Term
what are 5 things that increase risk for HF
Definition
smoking
HTN
no exercise
CAD/dyslipidemia
obesity
Term
when should you put a restriction on the exercise of patients
Definition
acute symtpoms of congestion (edema/hypervolemic)
Term
how should you adjust a HF patient's diet
Definition
moderate Na restriction
Term
what testing can be done if you are not sure of the diagnosis for a patient with SOB
Definition
BNP
Term
what does elevated BNP show
Definition
need to remove water- diuresis and natruresis
Term
therapeutic action in heart failure:
diuretics
Definition
decrease preload
Term
therapeutic action in heart failure:
ACEi
Definition
decrease preload, decrease afterload, decrease neurohormone tone
Term
therapeutic action in heart failure:
b-blocker
Definition
decrease nuerohormone tone
decrease chronotrope
Term
therapeutic action in heart failure:
digoxin
Definition
+ ionotrope, decrease neurohormone tone
Term
therapeutic action in heart failure:
hydralazine
Definition
decreases afterload
Term
therapeutic action in heart failure:
nitrates
Definition
decreases preload
Term
therapeutic action in heart failure:
aldosterone antagonists
Definition
decrease preload, decrease nuerohormone, decrease myocard fibrosis
Term
diuretics are used to relieve what symtpom?
Definition
edema/congestion
Term
what are sings of pulmonary edema- 2
Definition
inpsiratory crackeles
3rd heart sound
Term
what are signs of portal congestion-2
Definition
JVD
hepat-jugular refelx
Term
what do you use diuretic in combo with-2
Definition
another drug + Na restriction
Term
what effects does diuretics have on morbidity/mortality
Definition
unknown
Term
when do you use thiazide diuretics?
Definition
early stage of HF only!
Term
Loop diuretics given IV can do what
Definition
lower BP
Term
if a patient has impaired renal function what diuretic do you give
Definition
loop
Term
if patient has loop diuretic resistance what options are avilable-2
Definition
switch to diff loop
add thiazide
give IV bolus/ cont infusion
Term
what replacement do most patients taking loop diuretic receive
Definition
Potassium
Term
what drugs decreases morbidity and mortality -4
Definition
ARBs
ACEi
B blockers
aldosterone antags
Term
what drugs increase CO
Definition
ACEi
ARB
B-blockers
Term
what drugs are always indicated for reduced EF/ LVD-2?
what are they normally used together with?
Definition
ACei/ARB
B-blockers
Term
what drugs can be used as prevention for patients with a lot of risk factors for HF?
Definition
ACEi
ARB
Term
ADEs with ACEi/ARB
Definition
angioedema
hypotension
hyperkalemia
renal insuffienecy
Term
for which drugs do you monitor dry weight?
Definition
diuretic
B-blocker
Term
which drug can make you feel worse before making you feel better?
Definition
B-blocker
Term
which drug causes an increase in BP
Definition
digoxin
Term
what type of HF do you use digoxin in?
what is the only time you can use it in the other type?
Definition
systolic
if also have afib
Term
how long do you need to wait before checking digoxin levels?
Definition
1 week
Term
what are the two times to consider aldosterone antags-
Definition
LVDF after MI
HFrEF in Class III-IV HF
Term
Avoid aldosterone antags if Cr CL is below?
or K concentration is?
or Sr Cr > _ in men, _ in women
Definition
30
>5
>2.5; >2
Term
when using aldosterone antags, what medicaiotn should you avoid taking
Definition
NSAID
Term
whcih needs higher dose of hydralazine- HTN or HF
Definition
HF
Term
hydralalzine interferes with what progression?
nitrates effect what 2 things
Definition
HF
decrease night dyspnea & improve exercise
Term
what type of Ca blockers do you not use?
Definition
Non DHP
Term
how do you manage a patient with only diastolic dysfunction?
what are these? -4
Definition
treat risk factors to prevention systolic
-HTN, HR, dyslipidemia, CAD
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