Term
Calcium carbonate brand names |
|
Definition
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|
Term
|
Definition
|
|
Term
calcium carbonate indications |
|
Definition
most common oral prep for mild hypocalcemia, osteomalacia, rickets osteoporosis, renal osteodystrophy |
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|
Term
|
Definition
not absorbed well without HCl, take with food |
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|
Term
calcium carbonate side effects |
|
Definition
more GI effects than other preps, mild alkali syndrome leading to hypercalcemia, decreased PTH, hyperphosphatemia, kidney stones, renal failure |
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|
Term
calcium citrate brand name |
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Definition
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|
Term
|
Definition
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|
Term
|
Definition
more soluble, better BA, can be taken without food |
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Term
dibasic calcium phosphate |
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Definition
supplies both calcium and phosphate (oral) |
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Term
oral calcium salt side effects |
|
Definition
GI: constipation, intestinal bloating, gas (esp calcium carb) |
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Term
oral calcium salt interactions |
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Definition
decreased absorption of fluoride, iron, zinc, beta blockers, salicylates, phenytoin, bisphosphanates, tetracyclines, ciprofloxacin |
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Term
oral calcium salt new concerns |
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Definition
possible increased heart attack risk (no definitive evidence) |
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Term
calcium gluconate route of admin and % Ca |
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Definition
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|
Term
calcium gluconate indication |
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Definition
drug of choice for IV therapy in acute hypocalcemic tetany (least irritating to veins, infuse slowly to avoid arrhythmias) |
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Term
calcium gluceptate route of admin, % Ca, unique characteristic |
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Definition
IV or IM, 22% Ca, only one that is not irritating on IM injection |
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Term
cholecalciferol, route of admin, brand, and what is it? |
|
Definition
oral tablets, Delta-D, pure D3 |
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|
Term
ergocalciferol, route of admin, brands, what it is |
|
Definition
oral or IM, calciferol, drisdol, pure D2 |
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Term
dihydrotachysterol, brands, what it is, route of admin |
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Definition
DHT, Hytakerol, Roxane; reduced form of D2, oral |
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Term
dihydrotachysterol indication, for what population |
|
Definition
hyperparathyroidism secondary to renal failure, safer drug with renal failure (does not require renal 1-hydroxylation) |
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Term
doxercalciferol; brand, what it is |
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Definition
Hectoral, newer synthetic oral analog, doesn't require 1-hydroxylation (similar to dihydrotachysterol) |
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Term
calcifediol; brand, what population is it used in, route of admin |
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Definition
Calderol, does not require liver 25-hydroxylation, safer in liver disease, oral capsules |
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Term
Calcitriol, what it is, route of admin |
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Definition
1,25 OH2-D3, the final active hormone, no activation required, clinically most important, oral or injection |
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Term
paricalcitol and maxicalcitol; used for, route of admin |
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Definition
suppress excess PTH production without causing hypercalcemia; used in treating hyperparathyroidism but not for enhancing Ca abosrption, adminstered IV |
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|
Term
calcipotriene and calcitriol ointment; used for |
|
Definition
skin ointment preps approved for treatment of psoriasis (vitamin D3 analog) |
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Term
cinacalcet; brand, what it is, indication, advantage |
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Definition
Sensipar, new group of "calcium sensor mimetics", decreases amount of Ca needed to supress PTH release, used for hyperparathyroidism, normalizes serum calcium without altering bone density |
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Term
Calcitonin; what it is, MOA |
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Definition
32 aa polypeptide secreted from thyroid when hypercalcemic, decreases calcium release from bone (inhibits osteoclasts), stimulates calcium and phosphate excretion by kidneys, acts as agonist on calcitonin receptors (GPCRs that increase cAMP) |
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Term
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Definition
acute hypercalcemia, hyperphosphatemia, Paget's, osteoporosis |
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Term
bisphosphanates; structure and mechanism |
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Definition
analogs of pyrophosphate, bind bone matrix, inhibit osteoclasts, decrease bone turnover |
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Term
bisphosphanates; uses, advantages/disadvantages |
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Definition
Paget's, hypercalcemia, osteoporosis; oral, non-antigenic, cheaper, may decrease bone formation |
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|
Term
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Definition
poorly abosrbed, esp with food, should be taken on empty stomach, excreted by kidney (avoid renal), persist in bone for months/years |
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Term
bisphosphanate side effects |
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Definition
abdominal pain, nausea, diarrhea, vomiting, osteonecrosis of jaw (ONJ), femur fractures, esophageal cancer |
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|
Term
oral bisphophonate directions |
|
Definition
overnight fast, take while upright, lots of water, no food for 30 min, remain upright 30 minutes |
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|
Term
|
Definition
alendronate (generic), risedronate (delayed release prep), tiludronate, ibandronate (oral or IV) |
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|
Term
|
Definition
IV use for prevention and treatement, once per year or every other year injection, risk for renal impairment |
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|
Term
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Definition
oral (daily or monthly) or IV (every 3 months) |
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Term
teriparatide; brand, what is it, indications |
|
Definition
Forteo, synthetic human PTH [1-34], hypoparathyroidism, osteoporosis with high fracture risk or glucocorticoid-induced |
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|
Term
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Definition
first drug that clearly increases bone formation, daily injection stimulates bone (chronic presence decreases bone), daily SC injection, short action |
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Term
teriparatide side effects |
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Definition
nausea, cramps, headache, bone cancer concern |
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Term
denosumab; properties and mechanism |
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Definition
monoclonal antibody (peptide injection) against RANK-L (a cytokine that activates osteoclasts, promotes resorption), denosumab bind RANK-L and prevents RANK activtion (decreasing bone degradation) |
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Term
denosumab indication/dose |
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Definition
injection given twice per year for postmenopausal women with osteoporosis with history or high risk of fracture or failed other therapy, also to treat bone metastases |
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|
Term
|
Definition
long-term suppression: ONJ, fracture, delayed fracture healing side effects: back, muscle, bone pain, elevated cholesterol, urinary bladder infections |
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Term
denosumab contraindication |
|
Definition
patients with hypocalcemia |
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|
Term
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Definition
inhibits bone resorption, quite toxic, 3rd choice after calcitonin, bisphosphonates for hypercalcemia, Paget's, osteoporosis |
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Term
Plicamycin (aka mithramycin) |
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Definition
cytotoxic antibiotic that decreases plasma Ca by osteoclast toxicity, bone marrow suppression makes it useful in cancer, last resort for hypercalcemia, Paget's, osteoporosis; Useful for hypercalcemia of malignancy |
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|
Term
prednisone and other glucocorticoids |
|
Definition
decrease hypercalcemia by inhibiting gut Ca absorption and toxic to immune cells, danger of osteoporosis with long-term use |
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Term
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Definition
stimulates osteoblasts, increases bone formation, increases bone fragility at higher doses |
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|
Term
|
Definition
narrow therapeutic window, highly toxic due to inhibition of respiratory and glycolytic enzymes |
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|
Term
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Definition
IV Ca salts for acute tetany Oral Ca salts for longer-term therapy Vitamin D preparation plus adequate dietary Ca |
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|
Term
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Definition
treat cause - hyperparathyroidism, adrenocorticall deficiency Acute hypercalcemia: furosemide plus IV saline for diuresis and calciuresis Vitamin D toxicity, sarcoidosis: glucocorticoids hypercalcemia of malignancy: glucocorticoids, calcitonin, bisphosphonates, gallium nitrate, plicamycin |
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|
Term
|
Definition
replacement sex steroids plus Ca bisphosphonates calcitonin teriparatide |
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|
Term
therapy of Paget's disease |
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Definition
bisphosphonates, calcitonin, plicamycin |
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|
Term
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Definition
rapid first pass metabolism in liver when given orally |
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|
Term
slow-release depot forms of estradiol |
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Definition
estradiol valerate, estradiol cypionate |
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|
Term
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Definition
mainly used in HRT and hypogonadism |
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Term
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Definition
most common of several natural estrogen preps, contains estrone and estriol isolated from pregnant mare urine (Premarin) |
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Term
conjugated estrogen indications |
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Definition
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Term
ethinyl estradiol and mestranol (prodrug) |
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Definition
synthetic estradiol analog, ethinyl group slows metabolism, increases potency, oral effectiveness, commonly used in oral contraceptives and some use in HRT |
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Term
diethylstilbestrol (DES, Stilphostrol) |
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Definition
non-steroidal estrogen, oral, very potent, toxic, use in cancer |
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Term
low dose estrogens used for |
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Definition
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|
Term
higher dose estrogens used for |
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Definition
epiphysial closure, sexual development, gonadotropins for fertility |
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Term
oral contraceptives, HRT, oophorectomy treatment |
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Definition
estrogen in combination with progestin |
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Term
estrogens; minor side effects |
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Definition
nausea, edema most common, breast tenderness, hyperpigmentation |
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Term
estrogens; more significant side effects |
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Definition
migraine, cholestasis, insulin resistance, liver/gall bladder disease, thrombophlebitis, endometrial hyperplasia (cancer, decreased by including progestins), gynecomastia, teratogenesis, metabolic changes |
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|
Term
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Definition
IM, creams, suppositories, slow release IUD, micronized oral prep, safer than synthetic progestins for long term HRT use |
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Term
medoxyprogesterone acetate, hydroxyprogesterone caproate, megestrol acetate |
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Definition
synthetic progestin, structurally related to progesterone (21 carbons), exert mainly progesterone-like effects, for HRT, cancer, contraception |
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Term
norethindrone acetate, norgestrel, ethynodiol |
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Definition
synthetic progestin, structurally related to testosterone (18 carbons), aka impeded androgens, usually used in oral contraceptive |
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Term
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Definition
synthetic progestin, anti-androgenic and anti-mineralocorticoid, used in most popular new oral contraceptives |
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Term
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Definition
combo with estrogens for contraception/HRT, uterine bleeding due to endometrial hyperplasia, edometriosis, metastatic endometrial and breast cancer, diagnostic for estrogen secretion and endometrial responsiveness |
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Term
Progestin adverse effects |
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Definition
androgenic progestins: acne, weight gain, masculinization, altered libido, decreased HDL, increased LDL All progestins: menstrual changes, nausea, bloating, teratogenesis |
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Term
|
Definition
SERM, orally effective, used for agonist effect on bone (osteoporosis), no risk of cancer/uterine cancer because antagonist at these receptors, causes menopause symptoms and clotting |
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Term
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Definition
SERM, orally effective, long used as anti-estrogen, found to be agonist on some receptors, antagonist on breast (used for breast cancer prevention), uterine cancer risk, thrombosis risk, causes menopause symptoms, decrease osteoporosis and heart disease risk |
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Term
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Definition
first and only pure estrogen antagonist for breast cancer |
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Term
shared properties of combination oral contraceptive pills |
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Definition
most widely used contraceptives, all contain ethinyl estradiol or mestranol (few) plus a "19-nor" progestin (norethindrone, norgestrel/levonorgestrel, norgestimate, drosperinone), most are fixed combos (some employ sequential changes) |
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Term
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Definition
not androgenic or estrogenic used in combo with ethinyl estradiol |
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Term
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Definition
84 days of active pills, 7 days of inactive pill (1 period every 3 months) |
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Term
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Definition
similar to Seasonale but contains low ethinyl estradiol in final 7 pills |
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Term
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Definition
similar to Yasmin (has drosperinone as progestin) but has lower ethinyl estradiol and 24 active pills per 28 day cycle |
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Term
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Definition
24 instead of 21 active pills per 28 day cycle, ethinyl estradiol dose now only 10ug (lowest ever) |
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Term
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Definition
first continuous combo contraceptive, low dose ethinyl estradiol plus levonorgestrel, eliminates menstruation after some breakthrough spotting, similar to progestin-only pills |
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Term
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Definition
first combo contraceptive transdermal patch worn for 3 weeks, off for 1 week |
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Term
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Definition
new 3 week combo controceptive vaginal ring, ethinyl estradiol plus etonogestrel (a new progestin) |
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Term
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Definition
new chewable combo contraceptive |
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Term
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Definition
new four-phase pill oral estrogen (estradiol valerate) and new progestin (dienogest), estrogen alone on days 1-2 and 25-26 |
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Term
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Definition
inhibits ovulation by disrupting cyclical release of gonadotropins (example of feedback suppressive therapy) |
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Term
Combination Contraceptive pill adverse effects - minor |
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Definition
estrogen effects: nausea, irritability, headache, fluid retention, cyclic weight gain, breast enlargement/tenderness, menstrual changes, altered libido Progestin effects: Nausea, bloating, menstrual changes, depression, fatigue |
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Term
Combo contraceptives serious adverse effects |
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Definition
hypertension, lipid changes, clotting, stroke, MI, endometriosis (combos decrease), ovarian cancer, breast cancer, glucose intolerance, liver/gall bladder disease, teratogenesis |
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Term
Combo contraceptives contraindications |
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Definition
Absolute: pregnancy, estrogen-responsive tumor Relative: thromboembolic disease, HTN, diabetes, liver disease, smoking in older women |
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Term
OCs decrease response to these drugs |
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Definition
acetaminophen, warfarin, thyroxine, antidiabetic drugs |
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|
Term
OCs increase response to these drugs |
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Definition
cyclosporine, imipramine, theophylline, corticosteroids, BNZ |
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|
Term
OC efficacy reduced by these drugs |
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Definition
ampicillin, tetracycline, neomycin, rifampin, barbs, phenytoin, carbamazepine |
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Term
OCs efficacy increased by these drugs |
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Definition
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Term
norethindrone (Micronor) or norgesterel (Ovrette) |
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Definition
progestin only "mini-pills", avoid estrogen adverse effects, but less effective (99.5%), taken daily, lack of regular bleeding, ovulation still occurs, used when estrogens contraindicated (breast feeding, breast cancer, migraine, HTN, older smokers, liver/gall bladder disease, thrombotic disease) |
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Term
medroxyprogesterone acetate (Depo-Provera) |
|
Definition
IM injections every 3 months, concern due to possible toxicity, delayed recovery of fertility (not good for those that still desire pregnancy later) |
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Term
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Definition
single-rod implant inside upper arm, effective for 3 years, risk of irregular bleeding |
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Term
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Definition
emergency contraceptive containing levonorgestrel only, 2 pills within 72 hrs |
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Term
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Definition
emergency contraceptive, contains levonorgestrel only, 2 pills 12 hr apart within 72 hrs |
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Term
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Definition
emergency contraceptive, contains ulipristal (progesterone mixed agonist/antagonist related to mifepristone, an anti-progestin), can be taken up to 5 days after intercourse |
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Term
RU 486 - Mifepristone (Mifeprex) |
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Definition
abortefactient, progesterone receptor antagonist, disrupts maintenance of endometrium, also increases prostaglandin levels stimulating uterine contraction (induce safe abortion) |
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Term
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Definition
3 x 200 mg tablets in single dose on first day, if no abortion take 2 x 200 ug misoprostol tablets in single dose, on day 14 return visit to confirm termination (95% effective) |
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Term
Mifepristone/misoprostol adverse effects |
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Definition
vaginal bleeding, severe abdominal pain, transient nausea, vomiting, diarrhea, headache |
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Term
methotrexate plus misoprostol |
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Definition
not approved for abortion but effective and used, folic acid antagonist and cytotoxic to trophoblast |
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Term
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Definition
induce ovulation, dopamine agonist, orally effective, inhibits prolactin secretion by activating pituitary DA receptors |
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Term
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Definition
induce ovulation, weak androgen, orally effective, anti-estrogen to inhibit gonadotropin secretion, some progestin activity, used when ovulation prob due to endometriosis |
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Term
clomiphene (Clomid, Serophene) |
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Definition
induce ovulation, non-steroidal anti-estrogen, orally effective, reduces estrogen feedback inhibition of gonadotropin release, stimulates ovaries, also partial estrogen agonist, induces ovulation in 80%, 10% multiple births, causes ovary enlargement, menopause symptoms, used for oligospermia in males |
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Term
Human chorionic gonadotropin (hCG) (Profasi, APL) |
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Definition
peptide (IM), induce ovulation when pituitary defect, similar activity to LH, longer duration, from urine of preg women, also treat male infertility, hypogonadism in both sexes |
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Term
Menotropins (human menopausal gonadotropins, hMG, Pergonal) |
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Definition
peptide, induce ovulation when pituitary defect, LH and FSH activity, urine of postmeno women, used with hCG |
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Term
Ovulation induction regimen |
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Definition
low doses of menotropins plus hCG for 9-12 days for follicular development, then large dose of hCG alone for LH surge, induce ovulation (multiple births common), used in vitro fertilization, spermatogenesis |
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Term
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Definition
peptides, IM or SC (Urofollitropin, recombinant follitropin alpha subunit or beta subunit) |
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Term
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Definition
synthetic GnRH, pulsatile admin (mimic physio release pattern), when hypothalamus is defective |
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Term
oxytocin (Pitocin, Syntocinon) |
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Definition
augmentation of labor or induction (high dose), small peptide hormone from posterior pituitary, agonist at GPCR, stimulates uterine SM contraction, stimulates PG production |
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Term
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Definition
fetal HR closely monitored, too much uterine contraction can reduce fetal circulation, may need B2-adrenergic agonist |
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Term
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Definition
uterine contraction, small AA metabolites, act on GPCR to increase calcium, muscle contraction, induce cervical ripening at low doses |
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Term
dinoprostone, carboprost, misoprostol |
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Definition
prostaglandins, misoprostol has less GI effects and fever |
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Term
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Definition
second trimester abortions, often used together with other agents, local application of dinoprostone for cervical ripening |
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Term
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Definition
mediate painful contractions during dysmenorrhea (indomethacin, PG synthesis inhibitor effective therapy) |
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Term
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Definition
plant compounds, increase frequency/force of uterine contractions, contraindicated in HTN Preps include: ergonovine, methylergonovine Used for: post-partum or after abortion to control bleeding, maintain contraction |
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Term
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Definition
inhibit uterine motility, delay/prevent premature delivery, examples include: terbutaline, magnesium salts, nifedipine, nicardipine, indomethacin |
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Term
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Definition
most commonly used B2-adrenergic agonist for premature labor, IV to stop labor, then oral for maintenance, reflex tachycardia, increase cardiac output, hyperglycemia |
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Term
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Definition
eclamptic seizures (Mg sulfate), IV to inhibit uterine motility, Mg gluconate oral for maintenance, high concentrations can cause respiratory depression and cardiac arrest |
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|
Term
Nifedipine and nicardipine |
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Definition
effective tocolytic agents, calcium channel blockers, without reducing placental blood flow |
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|
Term
|
Definition
tocolytic, PG synthetase inhibitor, fetal/neonatal toxicities limit use |
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Term
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Definition
rapid metabolism, limited parenteral effectiveness, not orally effective, topical preps effective |
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Term
Andro LA, Depo-testosterone |
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Definition
testosterone esters, IM injection lasting 2-4 wks |
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|
Term
methyltestosterone (Android) |
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Definition
modified 17 alkyl to decrease metabolism, orally effective, androgenic steroid, hepatotoxic, short half life |
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|
Term
|
Definition
replacement therapy, anabolic effects, breast cancer, erythropoiesis in some types of anemia |
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Term
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Definition
17 alkyl testosterone analog, used in hereditary angioneuretic edema (liver effect) |
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Term
testosterone adverse effects |
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Definition
adverse effects: masculinization, feminization in men, testicular atrophy, prostate enlargement, acne, liver disease (17 alkyl synthetics), lipid changes, salt/water retention, HTN |
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|
Term
Oxandrolone, oxymetholone, stanozolol |
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Definition
higher ratio of anabolic to androgenic effectiveness, less masculinizing side effects, used by athletes, SARMS?, all are schedule III |
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|
Term
testosterone-like dietary supplements |
|
Definition
androstenedione, dehydroepiandrosterone (DHEA) |
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|
Term
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Definition
anti-androgen, GnRH analog, modified synthetic peptide, long DOA, reduces gonadotropin release (initially increase by desensitization) |
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Term
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Definition
used together to treat prostate cancer and hirsutism, anti-estrogen effects in breast cancer |
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|
Term
|
Definition
new GnRH antagonist analog, anti-androgen for advanced prostate cancer, peptide |
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|
Term
medroxyprogesterone acetate |
|
Definition
inhibit GnRH release, induce chemical castration for sex offenders |
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|
Term
|
Definition
orally effective non-steroidal androgen receptor antagonist, for prostate cancer, useful early in course of GnRH agonist therapy |
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|
Term
|
Definition
orally effective antagonist at mineralocorticoid and androgen receptors, also inhibits androgen synthesis, used alone or with oral contraceptives to treat hirsutism |
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|
Term
finasteride (propecia, proscar) |
|
Definition
orally effective 5a-reductase inhibitor, block conversion of testosterone to DHT, used for BPH, baldness |
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|
Term
|
Definition
class of viruses ssRNA that create dsDNA, HIV is example |
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|
Term
|
Definition
class of viruses ssRNA that create dsDNA copies, most efficient vector for gene delivery |
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|
Term
|
Definition
class of viruses with dsDNA, cause respiratory, intestinal and eye infections |
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|
Term
|
Definition
class of small, ssDNA, insert DNA on chromosome 19 |
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|
Term
|
Definition
class of dsDNA viruses, impact neurons |
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|
Term
Leber's congenital amaurosis (LCA) |
|
Definition
defect in RPE65, AAV used |
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|
Term
|
Definition
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|
Term
|
Definition
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|
Term
|
Definition
insert size 4.7 kb, high immune response |
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|
Term
|
Definition
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|
Term
|
Definition
integration occurs with this vector |
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Term
|
Definition
plasma/lipid complex contains DNA sequences encoding HLA-B7 and beta2 microglobulin, form a MCH Class I |
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Term
|
Definition
used by injecting directly into tumor lesion to direct an immune response against metastatic tumors |
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|
Term
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Definition
antisense phosphorothioate oligonucleotide, blocks replication of mRNA, 21 nucleotides long |
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|
Term
|
Definition
complimentary to mRNA transcribed from major immediate-early transcriptional unit of CMV, inhibits replication, used for local treatment of CMV retinitis with AIDS |
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|
Term
|
Definition
protein product of MDR1, functions as an efflux transporter for lipophilic xenobiotics |
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|
Term
|
Definition
MDR1 T/T mutation causes decreased concentrations of these chemotherapies |
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|
Term
|
Definition
anesthesia, patients with plasma cholinesterase deficiency remain paralyzed for longer, dibucaine number used |
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|
Term
|
Definition
slow acetylator gets peripheral neuropathy, rapid acetylator has potential therapy failure |
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Term
|
Definition
slow acetylator develops SLE, fast acetylator need higher doses |
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Term
|
Definition
slow acetylator has more bladder cancer, slow acetylator has less bladder cancer |
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|
Term
|
Definition
largest phenotypical variability among CYP family, more than 70 variant alleles |
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|
Term
|
Definition
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|
Term
|
Definition
|
|
Term
increased CYP2D6 activity |
|
Definition
|
|
Term
decreased CYP2D6 activity |
|
Definition
|
|
Term
|
Definition
extensive 2D6 activity means more morphine, PM means less analgesia |
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|
Term
|
Definition
EM 2D6 means mild side effects, PM means neurological problems |
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|
Term
|
Definition
EM 2D6 causes no change, PM causes no change |
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|
Term
|
Definition
2C9 most deficient activity alleles among ethnic groups, warfarin, tolbutamide and phenytoin |
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|
Term
|
Definition
taken up by nerve cells by same mechanisms as noradrenaline, message is not passed on, muscles relax, blood vessels widen, decreases BP |
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|
Term
debrisoquine-4-hydroxylase |
|
Definition
5-10% of caucasians are PM, caused by several mutant 2D6 alleles |
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|
Term
tamoxifen metabolic pathway |
|
Definition
metabolized by 2D6 and multiple other enzymes |
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|
Term
|
Definition
assumed to be more sensitive to mediaction, phase II metabolism appears to depressed |
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|
Term
liver metabolism in elderly |
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Definition
decreased phase I activity, CYP3A4 unchanged, 2D6/2C9/2C19/1A2 activities reduced |
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|
Term
barbs, diazepam, propranolol, verapamil |
|
Definition
high extraction ratio drugs, hepatic clearance, reduce doses |
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|
Term
ethanol, prazosin, warfarin |
|
Definition
low extraction ratio drugs, no change in dose |
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|
Term
|
Definition
1A2 inhibition, increased olanzepine, causes rigidity and falls, PK |
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|
Term
|
Definition
synergistic hypoglycemia, causes falls and fatigue, PD |
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|
Term
tolterodine and donepezil |
|
Definition
antagonism, causes decreased cognition, PD |
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|
Term
|
Definition
3A4 induction, decreased warfarin, increased risk of strokes, PD |
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|
Term
|
Definition
decreased platelet function, bleeding, herbal-drug interaction |
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|
Term
benzodiazepines and alcohol |
|
Definition
synergistic CNS depression, falls |
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|
Term
|
Definition
preferred antihypertensive, hypokalemia, hyperglycemia, hyperuricemia are more relevant due to arrhythmias, DM, and gout |
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|
Term
|
Definition
drug of choice for anti-inflammatory |
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|
Term
|
Definition
analgesic and atipyretic of choice during pregnancy |
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|
Term
cold medications with sympathomimetics |
|
Definition
may lead to vascular-mediated congenital defects in the fetus |
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|
Term
penicillins and cephalosporins |
|
Definition
safest for treatment of bacterial infections during pregnancy |
|
|
Term
|
Definition
gray baby syndrome, phase II glucuronidation deficient |
|
|
Term
carbamazepine and valproic acid |
|
Definition
dietary suppl with folic acid recommended to prevent neural tube defects |
|
|
Term
|
Definition
preferred antihypertensives in pregnancy |
|
|
Term
|
Definition
for acne vulgaris, highly teratogenic! |
|
|
Term
|
Definition
for psoriasis, highly teratogenic! |
|
|
Term
phenothiazines, metoclopramide and ondansetron |
|
Definition
used for N/V during pregnancy |
|
|
Term
|
Definition
used for diarrhea during pregnancy, poorly absorbed |
|
|