Term
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Definition
| Genes that stop or slow the cell cycle |
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Term
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Definition
| Genes that encourage cell growth by triggering specific phases in the cell cycle |
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Term
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Definition
-Gene that codes for regulatory transcription factors.
-Transcription factor that is like a brake for the cell cycle when there is damaged cell.
-When there is a mutation in p53 then the cell growth does not stop and will not kill the damaged cell and will instead continue to move through the cell cycle. |
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Term
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Definition
-Enzyme that modify chromatin and acetylate the positively charged lysine residues in histones.
-Those proteins can now act as binding sites for the chromatin remodeling complex that open the DNA. |
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Term
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Definition
| -Remove the acetyl groups added by the HATs |
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Term
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Definition
| Steps that make a mature mRNA from the primary RNA transcript. |
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Term
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Definition
| "Beads" on the string of chromatin that have the DNA rapped around it twice. |
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Term
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Definition
| Dna-associated proteins that are in chromatin and have about 8 of them in the nucleosome. |
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Term
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Definition
| enzyme that cuts DNA at random sites. |
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Term
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Definition
| of histones, it is usually associated with a positive control and means that there is an activation of genes through binding of a regulatory protein. |
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Term
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Definition
| Can either activate or inactivate depending on which histone and where the methyl group is located. |
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Term
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Definition
| patterns of inheritance that are not due to differences in DNA sequences, but histone modifications. |
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Term
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Definition
| -site in DNA where RNA polymerase binds to initiate transcription |
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Term
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Definition
| example of a promoter starting sequence. |
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Term
| Promoter-proximal elements |
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Definition
| Near the promotor site and the sequence is very specific for each gene. |
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Term
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Definition
| Proteins that bind to specific sites on other molecules and will mark things like viruses to be destroyed. |
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Term
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Definition
| DNA sequences spliced out of the primary mRNA transcript. |
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Term
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Definition
| Regions in the euk gene that are present in the mature RNA after splicing is done. |
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Term
| Regulatory Transcription Factor |
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Definition
| These are very particular proteins that bind to silencers, enhancer...etc to enhance a specific job at a specific time in a specific place. |
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Term
| Basal Transcription Factor |
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Definition
| Must be present for transcription to occur and bind with the promoter but are not specific to each cell type. |
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Term
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Definition
| Also help start transcription and will make a physical attach between the regulatory transcription factor and the Basal transcription factor. |
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Term
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Definition
| cutting of introns and exons and is controlled by proteins that bind to RNAs in the nucleus and interact with spliceosomes. |
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