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Exam 2 -physiology
nervous/endocrine/skeletal muscle
73
Physiology
Undergraduate 1
10/18/2012

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Term
Name of movement disorder that result from damage to the basal ganglia and an increased level of dopamine. It presents with increased muscle tone in all extremities and wide-based ataxic gait. This is a genetic disease.
Definition
Hunington chorea
Term
this is the name of a movement disorder that results from degeneration of dopamine-producing neurons in the substantia nigra. The symptoms of this condition worsen over time and often appear later in life. This disorder presents itself with slow movement and tremors
Definition
parkensons disease
Term
this is the name of a movement disorder that results in damage to the upper and lower motor neurons due to high levels of glutamate. This disorder presents with loss of coordination, muscle weakness and uncontrolled twitching
Definition
Amyotropic lateral sclerosis
Term
This is the name for the tract of neurons that are called the upper motor neurons that orginate in the primary motor cortex and cross over to the other side of the body.
Definition
pyramidal
Term
these neurons cross over to the other side of the body in the brain region
Definition
medulla oblongata
Term
name one specific endocrine function of the hypothalamus
Definition
secretion oxytocin
Term
name a specific function of the hypothalamus that is not related to the endocrine system
Definition
Body temperature regualation and vasopression
Term
what are two names for gray matter in the brain
Definition
basal nuclei and cerebral cortex
Term
A person has suffered from a stroke damaged Broca's area, would present with what types of symptoms?
Definition
Expressive Aphasia
Term
A person that has suffered a stroke that damaged the left occipital lobe would present with what symptom?
Definition
Visisual issues. partial or complete blindness
Term
What types of neurons make up a monosynaptic reflex?
Definition
sensory and motor
Term
Assuming that the person does end up getting bitten by their cat, their reflex response was not fast enough, how many neves does it take to get that information from the place on the skin where they were bitten to the cerebrum?
Definition
3
Term
Name one brain region that this ascending sensory information passes through on the way to the cerebrum?
Definition
Thalmus
Term
Indicate the final destination for this ascending sensory information that results in their awareness (perception) of being bitten, assume they were bitten on the right hand. Be specific as possible
Definition
left primary, somatic sensory cortex
Term
If someone put Neosporin on the bite to prevent infection, what brain region is used to make this decision
Definition
prefrontal cortex, parietal lobe of
Term
Name 2 functions attributed to the noradrenergic (norepinephrine) diffuse modulatory system system
Definition
attention, sleep awaking cycle, learning, memory, anxiety pain and mood
Term
name 2 functions attributed to the serotonergic (serotonon) diffuse modulatory system
Definition
pain, sleep awaking cycle,mood, emotional behavior problems
Term
how many efferent neurons are in an autonmic reflex
Definition
2
Term
what is the relationship between the anterior pituitary and the hypothalamus
Definition
it controls hormone secretion by the AP
Term
what is meant by the term permissiveness in regards to hormone action?
Definition
one it cannot fully even its effect unless another hormone is present.
Term
provide one specific example of synergism in regrds to the action of hormones.
Definition
epinephrine and gluagon
Term
The autonomic nervous system contains two divisions.
Definition
Sympathetic and Parasympathic
Term
in the autonomic nervous system which division causes the heart rate to increase.
Definition
sympathetic
Term
This is th name of the receptor that is found on skeletal muscles and binds to acetylcholine
Definition
nicotinic
Term
epinepherine and norepinephrine bind of these two types of receptors
Definition
alpha and beta
Term
this is the name for the little brain in the digestive system that controls the secretion and motility of the gut?
Definition
enternic nervous
Term
this is the name of the innermost membrane around the brain ans spinal cord that provides protection
Definition
pia matter
Term
someone tells you you are getting on their nerves, which gets you thinking about what nerves really are. What are nerves?
Definition
bundle of axons
Term
how many pairs of peripheral nerves (cranial + spinal) are in the body
Definition
12 crainal + 31 spinal = 43 pair
Term
what is the gray matter in the nervous system?
Definition
nerves of cell bodies
Term
acetycholineterase is responsible for terminating the action of acetycholine in the synapse. This is an example of what method of inactivating signaling at a synapse.
Definition
enzyme break down
Term
explain how a drug that is a serotonin-specific reuptake inhibitor will impact the ability of serotonin to act in the synapse
Definition
Increase serotonin levels in the synapse so increase action of serotonin or the post-synaptic neurons
Term
what is the function of the diencephalon in the brain?
Definition
•Motor Function Control
•Homeostasis
•Hearing, Vision, Smell, and Taste
•Touch Perception
Term
what is one function of the cerebellum in the brain?
Definition
balance and coordination
Term
agonist
Definition
molecule that combine with a receptor and mimic the reponse
Term
antagonist
Definition
one substance opposes the action of another
Term
what hormones are secreted by the posterior pituitary gland
Definition
oxytocin and vasopressin (ADH)
Term
What hormones are secreted by the anterior pituitary gland
Definition
prolactin, somatotropin, corticotropin, thyrotropin, follicle-stimulating hormone, and luteinzing hormone
Term
in general how do hormones exert their action on target cells?
Definition
must be transported by the blood to distant target cell, they bind to target cells receptors and initiate biochemical responses
Term
synergism
Definition
two or more hormones interact at their targets so that the combination yields a result that is greater than additive
Term
antagonism
Definition
tendency of one substance tooppose the action of another
Term
permissiveness
Definition
one hormone cannot fully exert its effects unless a second hormone is present
Term
compare and contrast the role of the hypothalamus in regards to the action of the anterior pituitary versus the posterior pituitary
Definition
the hypothalamus makes neurohormones which are then secreted by the posterior pituitary which helps maintain homeostasis in the body. the anterior pituitary is a true endocrine gland and secretes adenohypophseal hormones, but the hypothalamic neurohormones secreted by the posterior pituitary controls the anterior pituitary hormone production. In other words, the bypothalamic neurohormones is a tropic hormone to the adenohypopsheal hormones, because one controls the other secretions.
Term
what is the difference between a primary and secredary enocrine pathology
Definition
If a deficiency or excess arrise in the last enodocrine gland in a reflex, it is a primary pathology, while if the pathology is orginated in oneof the tissues producing trophic hormones, it is a secondary endocrine pathology
Term
Describe stroke
Definition
impaired body movement; usually one sided weakness, aphasia (expressive)
effects : broca area (L Cerebral hemishphere) and motor cortex
Term
Tourette syndrome
Definition
facial movement; fixation on spinning objects
effects: basal ganglia; dopamine; serotonin=old
Term
ALS (Amyotropic Lateral Sclerosis)
Definition
clumsy; muscle spasticity; tongue movement, difficulty swallowing, gag reflex
problem with UMN and LMN
High glutamate levels'basal ganglia
Term
Cerebellar ataxia
Definition
Speech difficulty; eye movements; limb control; dizziness; toluene exposure b/c of huffing
chemorecptors in the nose to the temporal lobe
Term
other than the type of initiating stimulus, what is the one difference between the stretch reflex and the golgi-tendon reflex
Definition
S=monosynaptic
GT=polysynaptic
Term
name two specific tissues that have excitatory muscarinic receptors. one subtype of cholingeric recptors
Definition
stomach, small intestine
Term
this is most common adrenergic receptor. This is a receptor that binds to norepinephrine or epinephrine
Definition
alpha 1
Term
the autonomic nervous system includes this many (a number) efferent neurons to each target tisseus
Definition
2
Term
the somatic nervous system includes this number of efferent neurons to each target tissue
Definition
1
Term
atrophine, a muscarinic antagonist, would do what to the activity of the heart? your answer would be to increase, decrease or no change
Definition
increase
Term
adipose tissue has this specific adrenergic receptor
?
Definition
B3
Term
THE GASTROINTESTINAL TRACT HAS THIS SPECIFIC ADRENERGIC RECEPTOR
Definition
alpha 2
Term
these two hormones are released by the postierior pituitary
Definition
vasopressin and oxytocin
Term
what specific tissue makes and release epinephrine
Definition
adrenal medulla
Term
In the autonomic nervous sytem, the neurons that have their cell bodies in the thoracic or lumbar region of the spinal cord are called?
Definition
sympathic post ganglonic neurons
Term
what neurotransmitters is released by the by the sympathetic post ganglonic neurons
Definition
norephineherine
Term
What is the principle nerve of the parasymphathetic nervous system
Definition
Vagus
Term
what neurotransmitter does the nerve that you named above question release onto target organs
Definition
acetycholine
Term
name 2 tissues that are only regulated by one division of the autonomic nervous system
Definition
adipose tissue and anterior veins
Term
Name 2 brain regions that are involved in the control of autonomic functions
Definition
hypothalamus and medulla oblongata
Term
jamie is the glucorticoid (prenisolne) to treat an inflammatory condition. What benefits would be derived from taking this drug
Definition
decreased immune response
Term
what effect would these pills have on Jamie's secretion of ACTH (A) and secretion of cortisol (B)
Definition
decrease and decrease
Term
sympotoms of hypothyroidism
Definition
cold intolerant, bradycardia and slow speech
Term
If samantha is taking the medication synthroid (T4) and the dose is too high, what would happen to the blood levels of T4 and TSH
Definition
T4 -would increase
TSH- decrease because of negative feedback
Term
what is the cause of graves disease?
Definition
Antibodies act like TSH so T3 /T4 levels are high
Term
If phenylepherine , an alpha agonist, was applied to blood vessels what would happen to the blood vessels as a result
Definition
constriction
Term
what are two specific actions of growth hormone
Definition
increase plasma glucose and increase in cartilage growth
Term
cushing syndrome may be caused by a tumor of the anterior pituitary or by a tumor of the adrenal cortex. explain how these 2 possibilities can distinguished from one another by measuring blood levels of ACTH and of cortisol
Definition
if anterior pituitary problem (2nd) then ACTH will be increased because that is what is causing increase cortisol. If the problem with adrenal cortex then ACTH will be low more to negative feedback.
Term
what are two symptoms that you might observe in a person with cushings syndrome
Definition
Moon face; buffalo hump
; abdominal fat with striations
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