Term
factor determining nature of post-synaptic potential in a synapse |
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Definition
the type of ion channel that receptor opens |
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Term
inhibitory post synaptic potential |
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Definition
Receptor causes K channels to open |
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Term
region where nt molecules exit from a post-syn cell into synapse |
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Definition
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Term
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Definition
interaction of excitatory and inhibitory synapses on a particular neuron. depolarization much be strong enough by the time it reaches the axon hillock to fire. |
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Term
Prevention of nt from staying in synaptic cleft |
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Definition
transporter molecules force nt back into cytoplasm |
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Term
brain has twice as many neurons as an adult brain-what is it? |
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Definition
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Term
when do you see a structure in a human embryo that could be called a brain |
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Definition
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Term
brain that is smooth with no grooves has how much surface area compared to real brain |
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Definition
1/3 the amount of surface of normal |
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Term
person with trouble drawing maps or following them has dmg to? |
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Definition
somatosensory assoc. cortex |
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Term
strongest evidence for learning to change structure of brain |
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Definition
evidence of neurogenesis is seen in the hippocampus, the area of brain involved in learning |
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Term
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Definition
anterior portion of cortex rostral to parietal and dorsal to temporal |
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Term
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Definition
layer of meninges that clings to the surface of the brain thin and delicate |
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Term
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Definition
peripheral nerve attached to the spinal cord |
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Term
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Definition
nucleus in thalamus receives inputs from the cerbellum sends axons to the primary motor cortex |
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Term
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Definition
bundle of spinal roots located caudal to the spinal cord |
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Term
action potential to terminal buttons then what happens? |
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Definition
voltage gated channel in pre-syn floods ca+ in as catalyst creating biochemical reaction. then vesicles of nt to to pre-syn. wall and vesicles fuse and release there contents by exocytosis. |
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Term
most common type of terminal button connection. Why most common? |
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Definition
axodentritic because of large surface area on dendritic spine and dendrite |
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Term
types of terminal button synapse |
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Definition
axodendritic axosomatic axoaxonic dendrodentritic |
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Term
function and locale of dendrodentritic synapse |
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Definition
common between dendritic field not mediated by nt but electic |
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Term
what happens when vesicles fuse to pre-syn membrane |
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Definition
surface area increase on pre-syn wall and portions of membrane near top of terminal button and reuses the membrane for new vesicles |
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Term
what causes nt to move across |
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Definition
diffusion across fluid filled cleft |
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Term
how did earlier scientists reason a chemical step was involved |
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Definition
due to the speed of effects of nt |
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Term
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Definition
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Term
primary structures located in cytoplasm of terminal button |
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Definition
mitochondria (button needs energy) and synaptic vesicles
and microtubules which transport btw soma and button |
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Term
post-syn membrane thicker? |
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Definition
because of protein receptors than accept nt and protein filaments that hold receptors in place |
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Term
receptors in post-syn membrane |
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Definition
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Term
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Definition
direct method protein then binds nt that opens or closes similar to earlier. faster than metabotropic |
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Term
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Definition
indirect method not an ion channel. nt binds then the G protein(inside membrane next to receptor) is activated which causes an enzyme to trigger the production of sec. messenger(cAMP) which cause ion channels in vicinity to open or close. biggest response and longest lasting |
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Term
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Definition
acts as a catalyst to do biochemical like turning genes off or on which terminates production of certain proteins |
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Term
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Definition
translation of biochemical to electrical with excitation or inhibition |
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Term
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Definition
excitatory post-syn potential na+ into cell |
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Term
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Definition
inhibitory post-syn potential K+ leave cell |
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Term
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Definition
during resting potential nothing happens due to diffusion and pressure. during depolarization the channel serves to neutralize the epsp. |
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Term
how to get soma to transmit another signal |
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Definition
positive ratio of epsp to ipsp |
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Term
difference in nt channel and voltage channel |
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Definition
nt gated don't follow cable conduction properties. no refractory period. the greater the nt the more affect/effect |
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Term
characteristics making axon hillock fire |
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Definition
spatial summation: different inputs production more stimulus temporal summation: time causing more firing on an input |
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Term
termination of post-syn potential |
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Definition
reuptake enzymatic deactivation |
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Term
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Definition
terminal buttons have transporters than pump nt back into cytoplasm |
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Term
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Definition
an enzyme destroys molecules of the nt i.e. breaks it apart into parts that don't bind |
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Term
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Definition
a receptor molecule located on a neuron that responds to the nt released by that neuron. located on the membrane on any part of cell like on terminal button. don't usually produce changes in membrane potential. regulate internal processes including synthesis and release of the nt. they are metabotropic most are inhibitory. |
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Term
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Definition
-not directly contribute to neural integration. -alter the amount of nt released by the terminal buttons of the post-syn axon -presyn modulation -presyn inhibition -pre-syn facilitation |
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Term
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Definition
decreases the release of nt of the button it is attached to |
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Term
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Definition
increases the release of nt |
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Term
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Definition
chemicals released by neurons that travel farther and are dispersed more widely than are nt. -are peptides i.e amino acids linked by peptide bonds |
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Term
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Definition
brain- cranial nerves (head and neck) spinal cord- spinal nerves (come of spinal cord) |
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Term
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Definition
imaginary line dividing body. running from forehead to base of spine |
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Term
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Definition
front of brain front of face |
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Term
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Definition
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Term
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Definition
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Term
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Definition
top of brain and head and back |
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Term
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Definition
toward the middle toward neuraxis |
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Term
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Definition
toward outside away from neuraxis |
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Term
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Definition
right arm is ipsilateral to right leg |
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Term
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Definition
right arm is contralateral to left arm |
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Term
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Definition
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Term
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Definition
point the axon crosses midline to contralateral side in reference to right brain controlling left side of body |
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Term
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Definition
toward a referent like toward cns |
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Term
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Definition
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Term
difference btw nerve and tract |
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Definition
both are collection of axons with nerve in pns and tract is in cns |
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Term
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Definition
neural tissue unpreserved color is cuz of high lipid in myelinated axon |
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Term
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Definition
neural tissue unpreserved color is cuz of no myeline lots of soma |
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Term
when do neurons become pns or cns |
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Definition
when neurons leave bone of cns they are pns |
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Term
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Definition
special cell evolved to act. glandular cell. auto and somatic regulate it. three types: skeletal(limbs move); cartiac(heart), smooth muscles(wall of uterus, hair folicles, in eye) |
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Term
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Definition
controlled by somatic physical behavioral response |
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Term
smooth muscle and cartiac and glands |
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Definition
controlled by autonomic skin temp, blood pressure, emotional |
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Term
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Definition
can be inhibited or enhanced. sympathetic(energy using) or parasympathetic (energy conserving) |
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Term
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Definition
efferent neurons to same muscle group producing different effects due to what system it goes through i.e. pyramidal or extra pyramidal. |
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Term
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Definition
in medulla shaped like pyramid neurons in motor system go through it fine motor skills bigger than other animals dominate in us regulated by cortex last to develop in children develops into early adulthood goes got smaller group muscles |
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Term
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Definition
don't go through pyramidal phylogenetically oldest (first things babies can do-not fine motor skills. brain dmg patients can still stand up. doesn't need cortex access) |
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Term
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Definition
-like pyramidal -small muscle groups doing highly skilled actions like moving eyes. -they leave brain through cranial nerves and go to head and neck and bypass the pyramids |
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Term
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Definition
fibers are in still in autonomic by are moved to somatic because they are sensory.
vision audition olfaction gustation somesthesis (proprioception &stereognosis;pain&temperature;light touch) |
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Term
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Definition
carried in same pathway as stereognosis. our ability to know where are limbs are in 3d receptors exist in muscles, tendons and joints and in inner ear(gravitational force or force from movement) |
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Term
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Definition
carried in same pathway as proprioception. know what 3d items is by touch only |
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Term
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Definition
same pathway carry both things. same type of receptor |
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Term
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Definition
ability to detect minute contact w/o reference to pressure sensors. the hair helps. and our skin is ridged and it increases sensibility to changes in texture |
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Term
frontal-coronal transverse plane |
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Definition
dorsal to ventral - perpendicular to ground- from posterior or anterior face |
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Term
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Definition
anterior to posterior-perpendicular to ground-divides brain into halves-separate medial from lateral |
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Term
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Definition
anterior to posterior-parallel to ground-as seen from above or beneath |
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Term
meninges in how many layers in cns |
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Definition
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Term
meninges in how many layers in pns |
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Definition
2-no arachnoid layer, so don't have to circulate csf |
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Term
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Definition
protective tissue. first layer is dura mater |
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Term
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Definition
hold skin in place. layer above bone |
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Term
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Definition
first layer in meninges hard to make out brain at this level can't tear by hand the skulls inner periosteum two layers of dura mater and one separates and creates cavity called venus sinus |
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Term
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Definition
arachnoid trabeculae protrude from it. |
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Term
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Definition
closely attached to brain and spinal cord, and following surface convolution. extracellular fluid is under pia mater |
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Term
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Definition
btw pia mater and the arachnoid membrane filled with cerebrospinal fluid |
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Term
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Definition
two of them. largest produces greatest amounts of csf |
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Term
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Definition
located at the midline , its walls divide the surrounding part of the brain into symmetrical halves |
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Term
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Definition
cerebral aqueduct runs the mid-line an connects to fourth ventricle underneath the cerebellum. |
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Term
csf fluid and development of spinal cord |
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Definition
central channel for csf before 20 yrs. after 20 csf leaves sides of 4th ventricle |
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Term
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Definition
most is in sub-arachnoid space but some is in ventricles |
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Term
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Definition
at mid-line is cerebral aqueduct that carries csf to fourth ventricle then csf flows down spinal cord |
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Term
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Definition
bridge of neural tissue that crosses through the middle of the third ventricle serving as reference |
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Term
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Definition
creates csf in all ventricles how? blood pressure from tissue in capillaries forces plasma like across semi permeable membrane. |
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Term
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Definition
protect brain from inertia support brain by lessening force of effective weight of brain (1400g->80g) |
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Term
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Definition
also called mid cerebral spilts the brain into two "hemispheres" |
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Term
right above corpus callosum |
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Definition
first original cortex that evolved |
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Term
what gives color of cortex |
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Definition
cell bodies on top of cortex |
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Term
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Definition
remove cortex and cerebellum and you have brain stem. -maintenance of life like aggression and food intake and mating |
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Term
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Definition
most visible -large % of total weight (40%) |
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Term
used to form landmarks in brain |
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Definition
sulci fissures gyri 2/3 of cortex isn't visible |
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
separates frontal from temporal and temporal from parietal also called sylvian fissure |
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Term
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Definition
fissure of rolondo separate frontal from parietal. splits the primary motor cortex from the primary somatosensory cortex |
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Term
a notch on bottom caudal area of cortex |
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Definition
separating occipital lob from parietal |
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Term
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Definition
also known as pre central gyrus on caudal end of frontal lobe. -topographical organization |
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Term
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Definition
-programs movement by retrieving info -the further you move anterior on the association cortex the move removed movement is from the primary motor cortex. -broca's area is anterior to the tongue section of the prim. motor cortex -planning gets worse if you dmg the anterior pole. |
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Term
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Definition
pyramidal extra pyramidal special muscle groups (in cranial nerves) |
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Term
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Definition
sympathetic parasympathetic |
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Term
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Definition
motor systems sensory systems |
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Term
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Definition
myelencephalon metencephalon mesencephalon diencephalon telencephalon |
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Term
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Definition
cervical (skull) thoracic lumbar sacral coccygeal(tail) |
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Term
primary somatosensory cortex |
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Definition
also called post central gyrus -senses of awareness of body |
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Term
somatosensory assoc. cortex |
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Definition
damage to:can't tell what is in hand (agnosia). the further posterior damage the harder to navigate 3d space. |
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Term
area at most posterior of lateral sulcus |
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Definition
visual and auditory linked with memory. wernicke's area. fluent meaningless afasia if damaged. |
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Term
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Definition
superior temporal gyrus inside lateral fissure. -auditory agnasia:can't tell perception of sound |
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Term
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Definition
involved with integration of several input |
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Term
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Definition
origin of cns. -hollow -closed at rostral end |
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Term
three major parts of brain |
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Definition
forebrain midbrain hindbrain |
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Term
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Definition
divides into three parts which become 2 lateral ventricles and third ventricle then the region around the lateral ventricles becomes the telencephalon (end brain) and the region around the third ventricle becomes the diencephalon(interbrain) |
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Term
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Definition
-mesencephalon -in final form chamber becomes narrow forming the cerebral aqueduct |
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Term
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Definition
surrounds the fourth ventricle metencephalon(afterbrain) myelencephalon (marrowbrain) |
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Term
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Definition
cells of the ventricular zone that divide and give rise to cells of the cns |
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Term
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Definition
layer of cells that line the inside of the neural tube;contains progenitor cells |
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Term
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Definition
division of each progenitor cell produces two new progenitor cells |
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Term
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Definition
progenitor cells form two different kinds of cells as they divide: another progenitor cell and a brain cell |
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Term
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Definition
first brain cells produced -cell bodies extend fibers from ventricular zone radially outward -fibers end at pia mater as feet and keep attached and grow -during apoptosis, some die and some become astrocytes or neurons |
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Term
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Definition
chemical signal for progenitor cells to die |
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Term
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Definition
cerebral cortex basal ganglia limbic system |
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Term
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Definition
thalamus hypothalamus -on either side of third ventricle -make up wall of ventricle |
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Term
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Definition
tectum tegmentum -cerebral aqueduct splits the above two |
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Term
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Definition
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Term
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Definition
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Term
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Definition
primary projection of olfaction. -juts out on ventrical side of medial temporal lobe |
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Term
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Definition
if damaged then visual field is effected in both eyes. located in occipital lobe in midline fissure (calcarine fissure) |
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Term
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Definition
blindness in visual field |
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Term
what is system is largest of cortex |
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Definition
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Term
visual association cortex |
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Definition
can't tell what you saw if you have damage to it. and can be highly specific to visual things you can or can not recognize |
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Term
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Definition
analysis of info -recognize events that occur one after another and controlling these |
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Term
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Definition
synthesis -putting isolated elements together to perceive things as a whole -read maps |
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Term
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Definition
collection of subcortical nuclei which lie beneath the anterior portion of lateral ventricles. -involved with movement -caudate nucleus -putamen -globus pallidus -highly processed/integrated info of body and environment. mainly extra pyramidal motor system(control of it originates here) |
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Term
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Definition
-surrounds the brain stem inside brain -next gen in evolution. motivation and emotion -helps us living in groups and develop sociality like maintaining aggression -hippocampus -amydala -septum -fornix -mammillary bodies -limbic cortex |
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Term
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Definition
-next to lateral ventricle under temporal lobe -acquisition of memory -remove this and never form long term memory |
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Term
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Definition
-attached to hippocampus -regulates emotional experience(activation and expression of emotion) -process happens more on right side;detecting nuanced emotional expression of others |
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Term
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Definition
-close to midline -a wall separated lateral ventricles -regulate expression of some reaction (impulse control) |
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Term
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Definition
arching axons info from hippo to hypot can initiate actions |
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Term
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Definition
-part of hypothalamus -wide variety of regulation (aggressive and maternal behavior) -fornix connects hippocampus with mam. bodies. |
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Term
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Definition
-above corpus callosum but not neocortex -more primitive with four layers and first to evolve -able to do most detailed processes like integration (waiting for right social context to speak) -prominent input from olfactory system -used to be called nose brain |
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Term
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Definition
-the biggest section of diencephalon -divided into distinct nuclear groups that are connected to distinct groups of pns (projection fibers) -cortical routing info to correct part of cortex (ever sense routed except olfaction) -sensory nuclei are unique for each sensory system -motor nuclei -assoc. nuclei-from multiple systems -non specific nuclei- poly modal info is transmitted to nuclear groups within thalamus and nuclear groups around thalamus -has crude consciousness like responding to pain and audition |
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Term
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Definition
-below thalamus -form floor and walls of third ventricle -critical for survival like behavior like maternal behavior and eating -four f's:fighting, fucking, fleeing, feeding -principal autonomic and endocrine system control -where hormones are produced -special system of blood vessels directly connects hypothalamus to anterior pituitary gland -hypothalamus produces the posterior pituitary gland hormones and directly controls there secretion |
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Term
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Definition
bridge of gray matter pierces middle of third ventricle |
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Term
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Definition
just in front of pituitary stalk. half of axons in the optic nerves from the eyes cross from one side of the brain to the other |
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Term
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Definition
located near base of pituitary stalk -specialized neurons that secrete hypothalamic hormones that stimulate the anterior pituitary gland to secrete its hormones |
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Term
how hypothalamus monitors endocrine system |
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Definition
-input from many sources (neurons) -rich blood supply to monitor -osmocepters:respond to osmolarity (how much fluid in blood i.e. as we lose water, protein is left behind it makes blood have a high osmodic force which draws water in) so these receptors may make u drink water -chemoceptors:chemical monitors of blood; blood level of hormones -thermoceptors- monitor temp of blood. can cause change in distribution of blood; can repress metabolic rate |
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Term
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Definition
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Term
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Definition
out/release-packets of secretory cells connect by a duct to surface of body or hollow organ in body examples sebaceous(oil for skin) sweat tears salivary prostate gall bladder pancreas(releasing into digestive tract) |
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Term
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Definition
-inside secreting-ductless glands surrounding by capillary cells so exocytosis to blood -examples: gonads(ovaries and testes) adrenal gland thyroid pancreas(insulin into blood) |
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Term
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Definition
endocrine control separate pocket of bone encases gland |
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Term
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Definition
-releases growth hormone -adrenocorticotropic(acth) -thyroid stimulate hormone -prolactin -gonadotropic follicle stimulating hormone Luteinizing hormone |
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Term
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Definition
-ACTH -stimulates cortex of adrenal gland -outer covering of adrenal regulates amount of glucose or salts excreted in urine -also sex hormones |
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Term
thyroid stimulating hormone |
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Definition
thyroxine -increase metabolic rate of all cells except gonads and adult brain -w/o-symptoms are depression, poor cold tolerance, not comfortable body temp.,retard in infants |
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Term
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Definition
-promotes lactation -generate cells to produce milk -works with estrogen -suppresses ovulation |
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Term
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Definition
-stimulates development of cells in ovaries and testes contents -stimulate production of gametes |
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Term
posterior pituitary gland |
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Definition
anti diuretic hormone oxytocin |
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Term
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Definition
how much water in kidneys? then extract from blood to urine -lose water in blood; so blood vessels constrict to make pressure go up |
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Term
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Definition
-activation of smooth muscles in uterus and around secretory cells of breasts i]contraction of milk producing cells so milk leaves breasts ii]strengthening and prolonging contraction of uterus |
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Term
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Definition
collection of cell bodies;integrating info -nucleus is in cns -ganglion is in pns |
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Term
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Definition
runs posterior to anterior in the saggital space. |
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Term
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Definition
contains blood that leaves head to heart |
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Term
muscle memory-which strutures |
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Definition
association motor cortex and cerebellum |
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Term
anterior vs posterior pituitary gland |
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Definition
-different classes of tissue -skin cells connected by blood supply on anterior and most secretion and bigger- adenohypophysis -posterior is neural connections- neurohypophysis -hypothalamus controls pituitary by blood -both have there hormone manufactured in hypothalamus and goes to blood stream -anterior localized blood stream release -posterior release in general blood system |
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Term
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Definition
anterior and posterior pituitary gland |
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Term
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Definition
-one for every one released in pituitary -excitatory/releasing and inhibiting(somatostatin) |
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Term
hypothalmic-hypophyseal portal system |
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Definition
the hypothalamus and hypophysis system of releasing hormones |
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Term
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Definition
-covering -periaqueductal gray matter -reticular formation -red nucleus and substantia nigra -cranial nerve 3(eye movement) and 4(muscle for the eye) |
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Term
periaqueductal gray matter |
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Definition
-surrounds the cerebral aqueduct as it travels from the third to fourth ventricle -receptors for species type behavior -receptors for opiates -pain transmission pathways |
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Term
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Definition
-net like -occupies core of brain stem, from the lower border of the medulla to the upper border of the midbrain -effect on arousal and sleep- activate cerebral cortex for muscle tonus |
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Term
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Definition
-part of motor control -extra pyramidal -bundle of axons constitutes one of the two major fiber systems that bring motor info from the cerebral cortex and cerebellum to spinal cord |
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Term
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Definition
-part of motor control -extra pyramidal -black substance(melanin) -the color is from the waste of producing dopamine -axons project to caudate nucleus and putamen |
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Term
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Definition
(from nigra to striped cells(corpus striatum) -muscle tone goes up and caudate nucleus gets dopamine and it regulates so your limbs don't get restricted -if damage to nigra person gets parkinson's so person's body gets tight and has tremors. extra pyramidal function is hurt -chewing gum will help person because they are willfully moving jaw |
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Term
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Definition
-the bulge on the brain stem -superior and inferior colliculi -one of places brain evolved to |
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Term
superior and inferior colliculi |
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Definition
-name for both together-corpora quadrigemina- bodies of 4 twins -final detail process of visual(superior-which allows for sight of colors and shapes and movements) and audition(inferior-which allows for location of sound) in sub human -in human this process is spinal reflex like hearing sound and flinching |
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Term
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Definition
-nuclei recieve projections from the cerebellar cortex and then send projections out of the cerebellum to other parts of the brain -superior, middle, and inferior peduncles connects cerebellum -facilitates smooth performance of behavior -from medial to lateral primitiveness moves to more advanced process(mammalia) - ours is more lateral -towards medial (archicerebellum) is first to evolve and this is entire cerebellum for fishes -next to evolve is paleocerebellum -next is neocerebellum |
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Term
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Definition
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Term
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Definition
connects pons and cerebellum -majority of information passes through here -connects to neocerebellum |
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Term
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Definition
cerebellum with medulla oblongata connection |
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Term
archicerebellum function in humans |
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Definition
connected to brain via inner ear so we can do big movements like counteract gravity if damaged then can't maintain posture or walk or sit |
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Term
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Definition
necessary for land creatures to walk and for limbs to coordinate and other unskilled behavior |
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Term
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Definition
only in mammalia and dominate part in us and responsible for learned actions -the size of neocerebellum follows and is followed by the size of the pons and cortex(they are joint processors) |
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Term
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Definition
-rapid opening and closing of hands can't be done -moving wrist from palm to top of hand -past pointing -close eyes and try to touch nose and person misses |
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Term
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Definition
-contains portion of reticular formation including some nuclei important for sleep and arousal -looks like a bridge connecting 2 parts of cerebellum -only in mammalia -fibers direct info from brain to cerebellum -left cerebellum receives info form right brain -cranial nerve 5-8 (relays info contra-laterally to/from cerebellum and cortex(pontine nuclei) |
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Term
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Definition
-contains part of the reticular formation, including nuclei that control vital functions such as regulation of the cardio system, respiration, and skeletal muscle tonus -looks like part of spinal cord -foramen magnum is the opening where spinal cord becomes brain -relays for body sense(somesthesis) -cranial nerves 8-12 -nerves cross here as well |
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Term
lateral geniculate nucleus |
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Definition
receives info from the eye and sends axons to the primary visual cortex |
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Term
medial geniculate nucleus |
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Definition
receives info from the inner ear and sends axons to the primary auditory cortex |
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