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Exam 2
Chapters 6, 7 and 8
88
Biology
Undergraduate 1
03/05/2009

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Term
Cell Theories
Definition

Virchow Hypothesis (1858):  All cells arise from pre-existing cells (all-cells-from-cells theory)

Hypothesis of spontaneous generation:  organisms arise spontaneously under certain conditions

Term
Modern Tenents of the Cell Theory
Definition

1) All organisms are made of cells

2) cells are derived from pre-existing cells

3)  cells contain hereditary infromation which is passed from cell to cell during cell division

4)  All cells are basically the same in chemical composition

5)  All energy flow of life occurs within cells

Term
Prokaryotes
Definition

have a cell membrane

contain genetic information in chromosomes

protein synthesis occurs via ribosomes

have an aqeous cytoplasm

lack nucleus and membrane-bound organelles

less than 10 micrometers

unicellular

circular DNA

create "capsule" to attach to other organisms

Term
Eukaryotes
Definition

have a cell membrane

contain genetic information in chromosomes

protein synthesis occurs via ribosomes

have an aqeous cytoplasm

have a nucleus and membrane-bound organelles

larger than 10 micrometers

hellical DNA

primarily multicellular

Term
Adaptive Advantages to organelle compartmentalization
Definition

1)  Molecules in chemical reactions do not need to diffuse across large distances

2) Allows incompatible chemical reactions to be separated

3) Increases the efficiency of chemical reactions

Term
nucleouls
Definition
darker, dense part of nucleus that forms ribosomes
Term
Rough Endoplasmic Reticulum (RER)
Definition

Exterior: ribosome attached to membrane-produces proteins

Interior: (lumen) new proteins are modified

Term
Smooth Endoplasmic Reticulum (SER)
Definition

smooth sac-like structure lacking ribosomes

produces lipid structures and breaks down hydrophobic molecules

Term
Golgi Apparatus
Definition

modify, store, ship, and route products of the ER

comprised of cisternae

Term
Cis face
Definition
closest to the ER-"recieving department"
Term
Trans face
Definition

farthest from ER-"Shipping Department"

sorts and sends products wherever they need to go

Term
Lysosomes
Definition
aid in intracellular digestion by phagocytosis (engulfing cell and digesting), enzymes dismantling and consuming, and autophagy (hydrolytic enzumes recycle the cells' own organic material)
Term
Food Vacuoles
Definition
formed by phagocytosis and its enzymes digest food
Term
Contractile Vacuoles
Definition
pump excess water out of freshwater protist's cells maintaining suitable concentrations of ions and molecules inside the cell
Term
Central Vacuoles
Definition
holds reserves of important organic compounds and is the cell's main repository of inorganic ions
Term

Mitochondria

Definition
The site of cellular respiration
Term
Chloroplasts
Definition
the site of photosynthesis
Term
Cellular Respiration
Definition
the metabolic process generating ATP by extracing energy from sugars, fats, and other fuels with the help of oxygen
Term
Photosynthesis
Definition

the process of converting solar energy to chemical energy by absorbing sunlight to drive the synthesis of organic compounds such as sugars from carbon dioxide and water

Term
Three compartments in the chloroplast
Definition

the intermembrane space

the stroma

the thalakoid space

Term
Perioxisomes
Definition
contain enzymes that transfer hydrogen from various substrates to O2 producing H2O
Term
Cytoskeleton
Definition
a network of fibers extending throughout the cytoplasm
Term
Microtubules
Definition
  • hollow tubes, walls consist of 13 columns of tubulin molecules
  • for maintenance of cell shape, cell motility, chromosome movements in cell division, and organelle movements
Term
Microfilaments
Definition
  • two intertwined strands of actin
  • used for maintenance of cell shape, changes in cell shape, muscle contraction, cytoplasmic streaming, cell motility, and cell division
Term
Intermediate Filaments
Definition
  • fibrous proteins supercoiled into thicker cables. Made of one of several different proteins of the keratin family depending on cell type
  • used for maintenance of cell shape, anchorage of nucleus and certain other organelles, and formation of nuclear lamina
Term
plasmodesmata
Definition

channels through the cell wall of plants allowing for things to pass through

Term

Desmosomes

Definition

act like "rivits" poping cells together to provide anchorage

Term
Gap Junctions
Definition
tie cells together and help with intercellular communication
Term
Tight Junctions
Definition
act like belts "sewing" the cells together
Term
Phospholipids
Definition
amphipathic because they have a hydrophillic head and hydrophobic tails.
Term
Components of the cell membrane
Definition
  • integral proteins
  • peripheral proteins
  • phospholipid bilayer
Term

Affect of Temperature on membrane fluidity

Definition

when the temperature raises things expande therefore lessoning permeability.

cholesterol is present in cells to help regulate this

Term
Cholesterol's role in maintaining membrane fluidity
Definition

In warm temperatures, it restrains the movement of phospholipids, reducing fluidity

In cool temperatures, it maintains fluidity by preventing the packing of molecules too tightly

Term
Perepheral membrane proteins
Definition
loosely bound to the surface of the molecule, connecting to integral proteins
Term
Integral membrane proteins
Definition
penetrate the hydrophobic come of the lipid bilayer spanning the membrane
Term
Major membrane protein functions
Definition
  1. transport
  2. enzymatic activity
  3. signal transduction
  4. cell-cell recognition
  5. intercellular joining
  6. attachment to the cytoskeleton and extracellular matrix (ECM)
Term
Membrane Cabohydrates and Cell-Cell Recognition
Definition
cells recognize one another by binding to surface molecules, which are often carbohydrates, on the plasma membrane
Term
Hydrophobic Molecules Crossing The Cell Membrane
Definition
they dissolve easily into the lipid bilayer and are able to cross it easily
Term
channel proteins
Definition
protiens built into the membrane and regulate transport
Term
transport proteins
Definition
have a hydrophyllic channell that certain molecules or atomic ions use as a tunnel through the membrane
Term
Diffusion
Definition
the movement of molecules of any substance so that they spread out evenly into the available space
Term
Why is diffusion a spontaneous process?
Definition
because diffusion moves things from a higher concentration into something with a lower concentration which is the way this naturally occurs
Term
concentration gradient
Definition
The region along which the density of a chemical substance decreases.  Allows only a certain amount to diffuse, so this amount is the potential.
Term
hypertonic
Definition
the solution with a higher concentration of solute
Term
hypotonic
Definition
the solution with a lower concentration of solute
Term
isotonic
Definition
same concentration of solute in both or all substances
Term
osmosis
Definition
The diffusion of water across a selectively permeable membrane.  Water diffuses from the area with lower solute concentration to the area with higher solute concentration because this will head toward an equal concentration in both areas.
Term
facilitated diffusion
Definition
polar molecules and ions impeded by the lipid bilayer of the memmbrane to diffuse passively are able to span the membrane with the help of transport proteins
Term
active transport
Definition
the cell must expend energy to help this substance through the membrane.  Transport proteins aid in this process
Term
Electrochemical gradient is produced by:
Definition
  • chemical force-the ion's concentration gradient
  • electric force-the effect of the membrane potential on the ion's movement
Term
pinocytosis
Definition
the cell "gulps" droplets of extracellular flluid into tiny vesicles
Term
phagocytosis
Definition
a cell engulfs a particle by wrapping around it and packaging it within a membrane-enclosed sac that can be large enough to be classified as a vacuole
Term
receptor-mediated endocytosis
Definition
enables the cell to acquire bulk quantities of specific substances
Term
exocytosis
Definition
the cell's secretions of certain biological molecules by the fusion of vesicles with the plasma membrane
Term
electrogenic pump
Definition
a transport protein that generates voltage across a membrane
Term
cotransport
Definition
a single ATP-powered pump that transports a specific solute can indirectly drive the active transport of several other solutes in this mechinism
Term
catabolic pathway
Definition
metabolic pathway that releases energy by breaking down complex molecules into simpler compounds
Term
anabolic pathway
Definition
consumes energy to build complicated molecules from simpler ones
Term
kinetic energy
Definition
energy associated with relative motion of objects
Term
potential energy
Definition
stored energy
Term
heat or thermal energy
Definition
kinetic energy associated with the random movement of atoms or molecules
Term
chemical energy
Definition
potential energy available for release in a chemical reaction
Term

First Law of Thermodynamics

Definition
Energy can be transferred and transformed, but it cannot be created or destroyed
Term
Second Law of Thermodynamics
Definition
Every energy transfer or transformation increases the entropy of the universe
Term
open systen
Definition
energy and matter can be transformed between the system and its surroundings
Term
closed or isolated system
Definition
unable to exchange energy or matter with its surroundings
Term
Exergonic Reactions
Definition
proceeds with a net release of free energy. ΔG is negative.  Magnitude of ΔG is the maximum amount of work the reaction can perform.
Term
Endergonic Reaction
Definition
Absorbs free energy from its surroundings and stores free energy in molecules.  ΔG is positive.  These reactions are nonspontaneous.
Term

Entropy

Definition
a measure of disorder or randomness
Term
Three Main kinds of Cellular Work
Definition
  1. Chemical work
  2. Transport work
  3. Mechanical work
Term
Chemical Work
Definition
the pushing of endergonic reactions which would not occur spontaneously
Term
Transport Work
Definition
the pumping of substances across membranes against the direction of spontaneous movement
Term
Mechanical Work
Definition
the beating of cilia, the contraction of muscle cells, or the movement of chromosomes during cellular reproduction are examples
Term
ATP
Definition

adenosine triphosphate

  • contains the sugar ribose, with the nitrogenous base adenine and a chain of three phosphate groups conded to it
  • belongs to the hydroxyl group
Term

How does ATP perform cellular work?

Definition

With the help of enzymes, the cell is able to use the energy released by ATP hydrolysis directly to drive the chemical reaction.

Term

The function of Enzymes:

Definition

Enzymes act as catalysts, speeding up a reaction without being consumed. 

Term
How do enzymes lower activation energy?
Definition
  • bring substances closer together
  • induce shape changes
  • provide favorable orientation
  • displace water
Term
substrate
Definition
chemical compound or structure that is being acted upon by the enzyme
Term
active site
Definition
area where the substrate can bind
Term
ES Complex
Definition
Enzyme-Substrate Complew-the enzyme wwith a substrate bound to it
Term
Cofactors
Definition
nonprotein molecules that stabilize the transitional state-coenzymes
Term
How do pH and temperature affect enzymatic activity?
Definition

enzymes have optimum themperature and pH ranges, so when they are in that range, the enzymatic activity will be greater than when it is unfavorable conditions

Term
Competitive Inhibitors
Definition
block substrate binding that the active site
Term
Non-competitive Inhibitors
Definition
bind to an alternative site on the enzyme changing the structural configuration
Term
Allosteric
Definition
protein's funtion at one site is affected by the binding at an alternative site
Term
allosteric activator
Definition
causes a reaction because it makes the enzyme more stable
Term
allosteric inhibitor
Definition
stabilizes the inactive form of enzyme
Term
Feedback Inhibition
Definition
product binding into the ehzyme allowing the reactant to build up and the product to be used (negative-feedback loop)
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