Term
|
Definition
the minumum amount of energy required by molecule for a reaction to occur
"the hump" |
|
|
Term
|
Definition
| thermodynamically unstable but kinetically stable |
|
|
Term
| Qualities of catalyst (4) |
|
Definition
decrease Ea
do not change delta G
form transient complex with substrate
not altered or changed |
|
|
Term
|
Definition
1. subrate binding specificity (active site)
2. induced fit model
3. substrate activation-bonds weakens
4. catalytic event
5. products released |
|
|
Term
|
Definition
|
|
Term
|
Definition
| the max speed at infinite substrate concentration |
|
|
Term
|
Definition
how well the enzyme binds to the substrate
if binding is good, km is low |
|
|
Term
|
Definition
| 1/v=(km/vmax)x(1/[s])+1/vmax |
|
|
Term
| y-intercept and x-intercept of L-B plot |
|
Definition
|
|
Term
| irreversable enzyme inhibition |
|
Definition
covalent bonds formed
(nerve gas inhibits Ache) |
|
|
Term
|
Definition
| non-covalent bonds formed |
|
|
Term
| compettitive inhibition (4) |
|
Definition
increases km
no change in vmax
binds to the same active site
at high [s], substrate will be favored |
|
|
Term
| non compettitive inhibition (4) |
|
Definition
doesnt bind to active site
decreases vmax
no change in km
changes induced fit |
|
|
Term
| 3 types of enzyme regulation |
|
Definition
1. substrate level regulation (inhibition of enzyme)
2. allosteric activation/inhibition
3. covalent modification |
|
|
Term
| covalent modification examples |
|
Definition
1. phosphorylation
2. cleavage |
|
|
Term
| allosteric activator/inhibitor |
|
Definition
binds to the regulatory subunit
makes change to catalytic subunit |
|
|
Term
how many ATP made in:
1.Glycolysis
2.TCA and OxPhos |
|
Definition
|
|
Term
|
Definition
| delayed onset muscle sorness |
|
|
Term
as ________ are flowing, _________ are pumped.
This reaction is (un)favorable? |
|
Definition
electrons, protons
favorable |
|
|
Term
| Inputs to TCA cycle (3 amino acids) |
|
Definition
Alanine-->pyruvate
Aspartate-->oxaloacetate
glutamate-->a-ketoglutamate |
|
|
Term
| movement of electrons in electron transport |
|
Definition
NADH-->complex1-->CoQ-->complex3-->CytC-->complex4-->Oxygen
succinate-->complex2-->CoQ |
|
|
Term
Who proposed the structure of F0F1 ATP synthase?
In what year? (same as dolly) |
|
Definition
|
|
