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Exam 2
Chapters 5,6,7,8,9
87
Biology
Undergraduate 1
03/06/2013

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Term
DNA
Definition

is a nucleic acid, a macromolecule that stores information. It consists of individual units called nucleotides

Term
Nucleotides
Definition
have 3 compents, a molecule of sugar, a phosphate group and a nitrogen containing molecule called a base
Term
Base Pairs
Definition
Adenine- Thymine and Guanine-Cytosine
Term
Double Helix
Definition
like a twisted ladder, two sugar phosphate strands spiral around each other forming the backbones of DNA. The bases attached to the sugar molecules on one strand bond to those attached to the other strand to form the rungs
Term
Genome
Definition

an organism’s complete set of DNA. In eukaryotes, this information can be found in the nucleus of almost every cell

Term
Chromosome
Definition
one or more unique pieces of DNA- circular in prokaryotes, linear in eukaryotes- that together make up an organisms genome. Chromsomes vary in length and can consist of hundreds of millions of base pair
Term
Gene
Definition
: a specific sequence of DNA
Term
Alleles
Definition
Different versions of a gene that code for the same trait
Term
Genotype
Definition
genes that an organism carries for a particular trait
Term
Phenotype
Definition
physical manifestations of the instructions
Term
Transcription
Definition
: the gene’s sequence is copied from DNA to a middleman molecule called mRNA
Term
Translation
Definition

the gene’s sequence is now encoded in mRNA, which directs the production of a protein

Term
Messenger RNA
Definition

: the genes code is copied in the mRNA and moves out of the nueclues into the cytoplasm, where protiens are built 

Term
Ribosomal subunits
Definition
: the protein-production factories where amino acids are linked together in the proper order to produce the protein 
Term
Transfer RNA
Definition

interpret the mRNA code, translating the language of DNA- coded in the linear sequence of bases- into the language of proteins, coded in the linear sequences of amino acids

Term
Codon
Definition

: matches with tRNA molecule that carries a particular amino acid


Term
Gene regulation
Definition
the question of whether a gene is turned on- producing its protein product- or turned off
Term
Promoter
Definition
region of DNA that RNA polymerase reconizes and binds to in order to produce an mRNA transcript of the genes 
Term
Operator
Definition

the region of DNA that a repressor protein can bind to and by doing so block RNA polymerase from transcribing the genes

Term
Regulatory genes
Definition
which can be located within the operon, near the operon or elsewhere in the genome- code for repressor proteins that impede 
Term
Mutation
Definition
when something occurs to alter the sequence of bases in DNA
Term
Biotechnology
Definition
in which organisms, cells, and their molecules are modified to achieve practical benefits
Term
Genetic engineering
Definition
the manipulation of organisms’ genetic material by adding, deleting or transplanting genes from one organism to another 
Term
Telomere
Definition

serves as a protective cap and is located at each tip of every chromosome, right next to the genes that direct the process that keep the organism alive (the telemeter in most human cells are long enough to support about 50 cell divisions)

Term
Histones
Definition
the long, linear strand is wrapped around proteins, which keep DNA from getting tangled and enable it to be tightly and efficiently packed in an orderly manner inside the cell  
Term
Binary fission
Definition
which means “division in two”
Term
Replication
Definition
the method by which a cell creates an exact duplicate of each chromosome 
Term
Parent cell
Definition
pinches the unit it divides into two new cells
Term
Daughter cell
Definition
the new cell is called the daughter cell
Term
Asexual reproduction
Definition

because the daughter cell inherit their DNA from a single parent cell and thus are genetically identical to the parent cell

Term
Sexual reproduction
Definition

a combination of DNA from two separate individuals is passed on to offspring

Term
Somatic cells
Definition
the cells forming the body of the organism 
Term
reproductive cells
Definition
are the sex cells or gametes
Term
Unwinding
Definition
 the coiled, double stranded DNA molecule unwinds and separates into two strands
Term
Rebuilding
Definition

enzymes connect a nucleotide with the appropriate base to the growing new strand, as the base bonds with the exposed, complementary base

Term
Allele
Definition
each of the two copies of the gene 
Term
Heredity
Definition

passing of characteristics from parents to offspring through their genes

Term
True breeding
Definition

always producing offspring with the same variant of the trait as the parents 

Term
Homozygous
Definition
when an individual inherits the same two allele for the gene
Term
Heterozygous
Definition
when an individual inherits a different allele from each parent 
Term
Mendel’s Law of Segregation
Definition
the idea that, of the two copies of each gene everyone carries, only one of the two alleles gets put into a gamete
Term
Punnett Square
Definition

we illustrate the cross between a true-breeding pigmented individual

Term
 Sex linked traits
Definition

traits that are controlled by genes on the sex chromosomes 

Term
incomplete dominance
Definition
: the phenotype of a heterozygous is intermediate between the phenotype of a heterozygote is intermediate between the phenotypes of the two homozygotes 
Term
codomninance
Definition
the heterozygote displays characteristics from both parents 
Term
multiple allelism
Definition

in which a single gene has more than two alleles 

Term
additive effects
Definition

describes what happens when the effects of alleles from multiple genes all contribute to the ultimate phenotype 

Term

Mendel’s Law of Independence

Definition

states one trait does not influence the inheritance of another trait 

Term
Linked genes
Definition

Alleles that are closely linked on the same chromosome will be passed on to off spring in one bundle

 

Term
population
Definition
specifically means a group of organisms of the same species living in a particular georgraphic region
Term
evolution
Definition
a change in allele frequencies of a population
Term
traits
Definition
physical charateristics
Term
fixation
Definition
geneti drift leads to fixation when an allele's frequency becomes 100% in a population
Term
genetic drift
Definition
a random change in allele frequencies in a population
Term
migration
Definition
gene flow; the movement of some individuals of a species from one population to another
Term
natural selection
Definition
1. There must be variation for the trait within a population
2. That variation must be heritable
3. individuals with one version of the trait must produce more offspring than those with a different version of that trait
Term
differential reproductive success
Definition
from all the variation existing in a population, individuals with traits most suited to reproduction in their enviroment generally leave more offspring than do individuals with other traits
Term
sexual selection
Definition
the natural selection for mating success
Term
stabilizing selection
Definition
is said to occur when individuals with intermediate phenotypes are the most fit
Term
biogeography
Definition
the study of distribution patterns of living organisms around the world
Term
vestigial structures
Definition
a structure once usuful to organisms, but which has lost its function over evolutionary time; ex molars in bats because they have a liquid diet
Term
insticts
Definition
innate behavior: dont require any enviromental input to develop ex: fixed action pattern
Term
Which of the following are always the same in every DNA molecule
Definition

a) the sugar

b) the base

c) the phosphate

d) only a and b are always the same

e) only a and c are always the same

Term

Genotype is to phenotype as

a) cookie is to oven

b) cookie is to recipe

c) cookie is to cookie

d) recipe is to cookie

e) oven is to cookie

Definition

a) cookie is to oven

b) cookie is to recipe

c) cookie is to cookie

d) recipe is to cookie

e) oven is to cookie

Term

During transcription, at the point at which the DNA strand being copied has an adenine, a(n) _____ is added to the _____.

a) thymine; tRNA

b) cytosine; DNA

c) uracil; tRNA

d) adenine; mRNA

e) uracil; mRNA

Definition

a) thymine; tRNA

b) cytosine; DNA

c) uracil; tRNA

d) adenine; mRNA

e) uracil; mRNA

Term

Deletions and substitutions are two types of point mutations. Which type is more likely to cause mistranslations of protiens?

a) substitutions, because they shift the reading frame and cause downstream amino acids to be changed

b) substitutions, because one protien is substituted for another protien.

c) deletions, because they shift the reading frame and cause downstram amino acids to be changed

d) deletions because one protein is deleted

Definition

a) substitutions, because they shift the reading frame and cause downstream amino acids to be changed

b) substitutions, because one protien is substituted for another protien.

c) deletions, because they shift the reading frame and cause downstram amino acids to be changed

d) deletions because one protein is deleted

Term

Which of the following statements about the metabolism of ethanol (which is present in alcoholic beverages) i incorrect?

a) individuals who provide non-functioning aldehyde dehydrogenase exhibit " fast flusing"

b) the process requires two enzymes; alcohol dehydrogenase and isopropyl dehydrogenase

c) individuals who are "fast flushers" are less likely to become alcoholics

d)aspirin interferes with the action of alcohol dehydrogenase

e) all of the above

Definition

a) individuals who provide non-functioning aldehyde dehydrogenase exhibit " fast flusing"

b) the process requires two enzymes; alcohol dehydrogenase and isopropyl dehydrogenase

c) individuals who are "fast flushers" are less likely to become alcoholics

d)aspirin interferes with the action of alcohol dehydrogenase

e) all of the above

Term

The polymerase chain reaction

a) makes it possible to create huge numbers of copies of timy pieces of DNA

b) enables researchers to determine the sequence of a complementary strand of DNA when they have only single stranded DNA

c) utikizes RNA polymerase to build strands of DNA

d) can create messanger RNA molecules from small pieces of DNA

e) all of the above

Definition

a) makes it possible to create huge numbers of copies of timy pieces of DNA

b) enables researchers to determine the sequence of a complementary strand of DNA when they have only single stranded DNA

c) utikizes RNA polymerase to build strands of DNA

d) can create messanger RNA molecules from small pieces of DNA

e) all of the above

Term
Which of the following is not a difficulty that medicine has encountered in its attempts to cure human diseases through gene therapy?
a) the transfer organism -- usually a virus -- may get into unintended cells and cause diseases
b)Its difficult to get the working gene into the specific cells where it is needed
c) It is difficult to get the working gene into enough cells at the right rate to have a physiological effect
d) For many diseases, a malfunctioning gene has not been identified
e) All of the above
Definition
a) the transfer organism -- usually a virus -- may get into unintended cells and cause diseases
b)Its difficult to get the working gene into the specific cells where it is needed
c) It is difficult to get the working gene into enough cells at the right rate to have a physiological effect
d) For many diseases, a malfunctioning gene has not been identified
e) All of the above
Term
Which of the following about Bt cyrstals is correct?
a) They are produced by soil-dwelling bacteria of the species Bacillus thuringiensis
b) The gene coding for the production of Bt cyrstals has been genetically engineered into the genome of dairy cows, increasing their milk production sixfold
c) They are produced by the polymerase chain reaction
d) they are produced by most weedy species of plants
e) all of the above
Definition
a) They are produced by soil-dwelling bacteria of the species Bacillus thuringiensis
b) The gene coding for the production of Bt cyrstals has been genetically engineered into the genome of dairy cows, increasing their milk production sixfold
c) They are produced by the polymerase chain reaction *****
d) they are produced by most weedy species of plants
e) all of the above
Term
Which of the following about telomeres is incorrecct?
a) they function like a counter, keeping track of how many times a cell has divided
b) At birth, they are long enough to permit approximately 50 cell divisions in most cells
c) they are slightly shorter in prokaryotic cells than in eukarotic cells
d) they funtion like a protective cap on chromosomes
e) they contain no critical genes
Definition
a) they function like a counter, keeping track of how many times a cell has divided
b) At birth, they are long enough to permit approximately 50 cell divisions in most cells
c) they are slightly shorter in prokaryotic cells than in eukarotic cells****
d) they funtion like a protective cap on chromosomes
e) they contain no critical genes
Term
prokaryotic cell divide via
a) mitosis
b) binary fission
c) meiosis
d) both mitosis and binary fission
e) none of the above
Definition
a) mitosis
b) binary fission***
c) meiosis
d) both mitosis and binary fission
e) none of the above
Term
In multicellular organsims, cells that undergo mitotic division but not meiotic division are called _____ cells
a) somosis
b) skin
c) interphase
d) somatic
e) germ
Definition
a) somosis
b) skin
c) interphase
d) somatic
e) germ***
Term
The ____ marks the break in the cell cycle between the end of mitosis and begining of the DNA synthesis stage
a) mitotic phase
b) synthesis phase
c) Gap 2 phase
d) Gap 1 phase
e) none of the above
Definition
a) mitotic phase
b) synthesis phase
c) Gap 2 phase
d) Gap 1 phase***
e) none of the above
Term
Mitosis results in:
a) daughter cells with twice as much genetic material as the parent cell and a unique collection of alleles
b) eight daughter cells
c) daughter cells with the same number and composition of chromosomes
d)gametes
e) daughter cells with the same number of chromosomes but different combinations of alleles
Definition
a) daughter cells with twice as much genetic material as the parent cell and a unique collection of alleles
b) eight daughter cells
c) daughter cells with the same number and composition of chromosomes***
d)gametes
e) daughter cells with the same number of chromosomes but different combinations of alleles
Term
Using a light microscope, it is eaiser to see chomosomes:
a) during mitosis and meiosis, because the condensed chromosomes are thicker and therefore more prominent
b) during interphase, when they are concentrated in the nucleus
c) in the mitochondria, because the chromosomes are circular
d) during asexual reproduction
e) during interphase, because they are uncoiled and have a more linear structure
Definition
a) during mitosis and meiosis, because the condensed chromosomes are thicker and therefore more prominent***
b) during interphase, when they are concentrated in the nucleus
c) in the mitochondria, because the chromosomes are circular
d) during asexual reproduction
e) during interphase, because they are uncoiled and have a more linear structure
Term
The division of the cytoplasm during cell division is referred to as:
a) cytoplasm splicing
b) cytokinesis
c) vegetative growth
d) cytodivision
e) hybernation
Definition
a) cytoplasm splicing
b) cytokinesis***
c) vegetative growth
d) cytodivision
e) hybernation
Term
Which of the following statements about a tumor is correct?
a) benign tumors pose less of a health risk than malignant tumore
b) Malignant tumors shed cancer cells that can spread to other parts of the body
c) tumors are caused by excessive growth and division
d) Cancer cells from malignant tumors can travel to other parts of the body in a process called metastasis
e) they contain c ells with abnormally high contact inhibition
Definition
a) benign tumors pose less of a health risk than malignant tumore
b) Malignant tumors shed cancer cells that can spread to other parts of the body
c) tumors are caused by excessive growth and division
d) Cancer cells from malignant tumors can travel to other parts of the body in a process called metastasis
e) they contain c ells with abnormally high contact inhibition***
Term
During meiosis but not mitosis:
a) haploid gametes are produced that are all identical in their allelic composition
b) division of the cytoplasm occurs
c) chromosomes line up in the center of the cell during meteaphase
d) genetic variation among the daughter cells is increased
e) two identical daughter cells are produced
Definition
a) haploid gametes are produced that are all identical in their allelic composition
b) division of the cytoplasm occurs
c) chromosomes line up in the center of the cell during meteaphase
d) genetic variation among the daughter cells is increased****
e) two identical daughter cells are produced
Term
Sister chromatids are:
a) the result of crossing over
b) identical molecules of DNA resulting from replication
c) homologous chromosomes
d) produced in meiosis but not mitosis
e) single-standed
Definition
a) the result of crossing over
b) identical molecules of DNA**** resulting from replication
c) homologous chromosomes
d) produced in meiosis but
Term
Which of the following occurs during prophase I of meiosis?
a) spindle fibers form
b) Homologous pairs of chromosomes align at the metaphase plate
c) Homologues come very close together
d) crossing over occurs between sister chromotids
e) chromosomes condense
Definition
a) spindle fibers form
b) Homologous pairs of chromosomes align at the metaphase plate***
c) Homologues come very close together
d) crossing over occurs between sister chromotids
e) chromosomes condense
Term
What type of chromosomal abnormality leads to the phenotype known as Downs syndrome?
a) trisomy 21
b) momosomny 21
c) monosomy 22
d) trisomy 22
e) disomy 21
Definition
a) trisomy 21***
b) momosomny 21
c) monosomy 22
d) trisomy 22
e) disomy 21
Term
Nondisjunction
a) is unequal division of the genetic materail during cell division
b) occurs during meiosis but not mitosis
c) occurs in males but not females among mammals, and in females but not males among birds
d) leads to a missing or extra chromosome
e) both A and D
Definition
a) is unequal division of the genetic materail during cell division
b) occurs during meiosis but not mitosis
c) occurs in males but not females among mammals, and in females but not males among birds
d) leads to a missing or extra chromosome
e) both A and D ****
Term
Traits that are determined by a single gene:
a) occur in single-celled organisms, but not in humans
b) are common in humans
c) must occur on the X chromosomes, because males have only a single X and so the gene must be able to function in the absence of its homologous allele
d) include eye and skin color
e) can only have two alleles
Definition
a) occur in single-celled organisms, but not in humans
b) are common in humans****
c) must occur on the X chromosomes, because males have only a single X and so the gene must be able to function in the absence of its homologous allele
d) include eye and skin color
e) can only have two alleles
Term
Which of the following is correct requarding pedigree analysis?
a) darkened squares or circles always represent individuals with the trait being traced
b) white squares always represent heterozygous individuals
c) horizontal lines connect sibilings
d) the length of the vertical line is dependent on the relatedness between two individuals
e) squares represent females, and circles represent males
Definition
a) darkened squares or circles always represent individuals with the trait being traced****
b) white squares always represent heterozygous individuals
c) horizontal lines connect sibilings
d) the length of the vertical line is dependent on the relatedness between two individuals
e) squares represent females, and circles represent males
Term
Which of the following traits shows a polygenic method of inheritance?
a) flower color in snapdragons
b) blood type in humans
c) seed color in peas
d) sickle- cell disease in humans
e) skin color in humans
Definition
a) flower color in snapdragons
b) blood type in humans
c) seed color in peas
d) sickle- cell disease in humans
e) skin color in humans ****
Term
The impact of a single gene on more than one characteristic is called:
a) incomplete dominance
b) environmentalism
c) balanced polymorphism
d) pleiotrophy
e) codominance
Definition
a) incomplete dominance
b) environmentalism
c) balanced polymorphism
d) pleiotrophy ****
e) codominance
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