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Exam 2
Nutritional Biocehm
82
Other
Undergraduate 2
03/03/2011

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Cards

Term
What are the three things that carbohydrates are made up of?
Definition
1. monosccharides
2.disaccharides
3. polysaccharides
Term
What is the general formula of sugars and polysaccharides?
Definition
(CH2O)n
Term
What type of carbohydrate are adlehydes and ketones?
Definition
Sugars and Polysaccharides
Term
What type of carbohydrate is a Saccharide?
Definition
simple carb.
Term
How many carbons are in a monosaccharide, disaccharide, poly?
Definition
1. one
2. two
3. three or more monosacc.
Term
What are the subunits linked by in carbohydrates?
Definition
Glycosidic
Term
What is dehydration synthesis?
Definition
Loss of water in a polymerization reaction
Term
What are the four major tissue layers of the digestive tract?
Definition
1. mucosa
2. submucosa
3. muscularis
4. serosa
Term
Function of salivary glands?
Definition
acessory organ, release a mixutre of water, mucus, and enzymes
Term
Function of Liver
Definition
acessory organ. produces bile, an important secretion needed for lipid digestion
Term
Function of Gallbladder?
Definition
acessory organ. stores and releases bile needed for lipid digestion
Term
Function of pancreas?
Definition
accessory organ. releases pancreatic jouce that neutralizes chyme and contains enzymes needed for carbohydrate, protein, and lipid digestion
Term
Function of mouth?
Definition
GI organ. mechanical breakdown, moistening, and mixing of food with saliva
Term
Function of pharynx?
Definition
GI organ. propels food from the back of the oral cavity into the esophagus
Term
Function of esophagus?
Definition
GI organ. transports food from the pharynx to the stomach
Term
Function of the stomach?
Definition
GI organ. muscular contractions mix food with gastric juice, causing the chemical and physical breakdown of food into chyme
Term
Function of small intestine?
Definition
GI organ. major site of enzymatic digestion and nutrient absorption
Term
Function of the large intestine?
Definition
GI organ. receives and prepares undigested food to be eliminated from the body as feces
Term
What's the function of the muscularis in the GI tract?
Definition
-two layers of smooth muscle- longitudinal muscle and circular muscle
-responsible for GI motility
-nerves embedded b/n muscle layers
Term
Whats the function of the submucousa?
Definition
-layer of connective tissue b/n muscularis and muscousa
-Lymphatic vessels (filled with lymph) carry insoluble fats away from GI tract
-Nerves regulate release of GI secretion
-Blood vessels carry soluble nutrients away from GI tract
Term
What is Transit time?
Definition
-Time between the consumption of food and its elimination as solid waste
-Usually 24 to 72 hours
-Affected by diet, illness, medications, physical activity, emotions
Term
Whats a spinhcter?
Definition
-Muscular band that narrows an opening between GI tract organs
-Keeps food in place long enough for digestive events to be completed
Term
What are the two types of GI tract movement?
Definition
-Segmentation
-Circular muscle movement that moves the contents back and forth within a small region of the GI tract

-Peristalsis
-Waves of longitudinal muscle contractions that move materials in the GI tract in a forward direction
Term
What is made up of GI secretions?
Definition
-GI secretions (digestive juices) include water, acid, electrolytes, mucus, salts, enzymes, bile, bicarbonate, etc
Term
What organs release digestive secretions?
Definition
-Organs that release digestive juices include salivary glands, stomach, pancreas, gallbladder, small intestine, and large intestine
Term
What is the purpose of digestive enzymes?
Definition
-Biological catalysts that facilitate hydrolysis, resulting in breakdown of large molecules into small components
Term
Whats the function of the mucous?
Definition
-Coats and protects mucous membranes
Term
What coordinate GI motions and secretions?
Definition
-Neural and hormonal signals coordinate
-3 regulatory control mechanisms, two neural and one hormonal
Term
What's the Enteric nervous system?
Definition
-Neurons located within the submucosa and muscularis layers
-Receives information from sensory receptors, chemoreceptors, and mechanoreceptors
Term
What's the Central nervous system?
Definition
-Sensory and emotional stimuli
Term
What's the function of the GI hormones?
Definition
-Hormones secreted by the mucosal lining of the GI tract regulate GI motility and secretion
-Some affect the brain to influence appetite (example: ghrelin stimulates hunger)
Term
What are the 3 phases of digestion?
Definition
1.Cephalic phase
2.Gastric phase
3.Intestinal phase
Term
What's the function of Cephalic Phase?
Definition
-Response of the central nervous system to sensory stimuli (smell, sight, taste) before food enters the GI tract
-Increased GI motility
-Release of GI secretions
Term
Whats the function of the gastric phase?
Definition
Response stimulated by the arrival of food into the stomach
-Increased GI motility
-Release of GI secretions
Term
Whats the function of the intestinal phase?
Definition
Response to chyme entering the small intestine
-Decrease in gastric motility
-Decrease in secretion of gastric juices
-Hormonal signals stimulate pancreas and gallbladder
Term
Whats the purpose of saliva?
Definition
-Moistens food and starts digestion
-Contains water, mucus, digestive enzymes, antibacterial agents
-Essential to sensations of taste (salty, sour, sweet, bitter, umami)
Term
What moves bolus down the esophagus to the stomach?
Definition
-Peristaltis
-Stretch receptors signal the gastroesophageal sphincter to allow the bolus to enter the stomach
Term
Whats Dysphagia?
Definition
-Difficulty swallowing resulting from injury or disease
Term
What are the 3 regions of the Stomach?
Definition
-fundus, body, and antrum
Term
What regulates movement of food into the duodenum?
Definition
-Pyloric sphincter
Term
What produce and release hormones into the blood?
Definition
-Endocrine cells
Term
What produce and release secretions into the stomach via ducts?
Definition
-Exocrine cells
Term
What release the hormone gastrin, which stimulates production and release of gastric juice?
Definition
-Endocrine cells in gastric pits
Term
What's the function of gastric?
Definition
-Stimulates release of hydrochloric acid and intrinsic factor from parietal cells
-Stimulates release of the protein-digesting enzyme pepsin from chief cells
Term
What's in gastic juice?
Definition
-Contains water, hydrochloric acid, digestive enzymes, mucus, and intrinsic factor (needed for vitamin B12 absorption)
Term
What's the major component of gastic juice? and What's its function?
Definition
-Hydrochloric acid (HCl)
-Dissolves food particles, destroys bacteria, provides optimal acidity (pH 2) for digestive enzymes to function
Term
What are two common GI disorders?
Definition
-GI ulcers (peptic ulcers) erode the mucosal lining of the esophagus, stomach (gastric ulcer) or duodenum

-Gastroesophageal reflux disease (GERD) allows acidic chyme back into the esophagus
Term
80% of peptic ulcers are caused...
Definition
bacterial infection (H. pylori)
-Common symptoms: dull pain in stomach relieved by eating

Treatment includes antibiotics and acid blockers
Term
What's GERD?
Definition
-Exposure to acidic reflux irritates the esophageal lining

Common symptoms: burning sensation in upper chest
Term
What's involved in Gastric emptying?
Definition
-Food leaves the stomach and enters the small intestine
Rate influenced by volume, consistency, composition of chyme
Term
What slows gastric emptying?
Definition
Hormone cholecystokinin (CCK)
Term
Whats the function of the small intestine and what are the three regions?
Definition
-Primary site of chemical digestion and nutrient absorption

Three regions
duodenum
jejunum
ileum
Term
Whats the function of the duodenum?
Definition
-Receives secretions from the gallbladder (bile) and pancreas through ducts


-Folds (plica circulares) covered with projections (villi) increase surface area

-Epithelial cells (enterocytes) covered with small microvilli make up the absorptive surface (brush border)
Term
What occurs in the brush border?
Definition
-Final nutrient digestion and absorption
Term
How does the brush border work?
Definition
Each villus contains blood capillaries and lymphatic vessels (lacteals) that move nutrients away from the small intestine
Term
What coordinate release of secretions from pancreas and gallbladder, relaxation of sphincters, and GI motility?
Definition
-Hormones CCK and secretin
Term
What stimulate release of pancreatic secretions ?
Definition
Secretin and CCK
Term
What is bile?
Definition
-needed for fat digestion
Made by the liver
-Stored and released by the gallbladder
-Contains bile acids, cholesterol, water, and bilirubin
Term
What empties bile into the duodenum
Definition
-Gallbladder
Term
whats the function of bile acid?
Definition
-break fats into smaller droplets so enzymes can digest them
Term
What? is reabsorbed through the ileum and returned to the liver via the hepatic portal vein?
Definition
bile
Term
What is the Basolateral membrane?
Definition
-Enterocyte membrane that faces away from the lumen and toward the submucosa
Term
What is bioavialability?
Definition
The extent to which nutrients are absorbed into blood or lymph
Influenced by physiological conditions, dietary components, and some medications
Example: vitamin D required for calcium absorption
Term
What is Celiac Disease?
Definition
-(gluten-sensitive enteropathy)
-Autoimmune response to the protein gluten that damages the absorptive surface of the small intestine
-Requires special gluten-free diet
Term
Whats the function of the cardiovascular system?
Definition
-Delivers nutrients and oxygen to cells, removes metabolic waste products

-Consists of two loops
Systemic circulation
Pulmonary circulation

-Arteries carry blood away from the heart; veins carry blood to the heart
Term
What's systemic circulation?
Definition
-Delivers oxygenated blood to all body organs except the lungs
-Blood flows from the left side of the heart, through the aorta, arteries and arterioles to capillary beds
-Blood returns to the heart through venules and veins
Term
WHats the function of the capillaries?
Definition
-Materials are exchanged between blood and tissues through the thin walls of microscopic capillaries
-Nutrients and oxygen pass into the interstitial fluid
-Waste from interstitial fluid is taken up and carried away
Term
Whats the purpose of the kidneys?
Definition
Breakdown of nutrients in cells produces a variety of wastes removed from the body
Term
What are Nephrons?
Definition
-Functional units of the kidney that remove wastes such as urea from blood and form urine
Term
What are the regions of the large intestine?
Definition
Cecum (with appendix attached)
Colon (ascending, transverse, descending, and sigmoid)
Rectum
Anal canal (and anal sphincters)
Term
What are the functions of the LI?
Definition
-Haustral contractions move contents back and forth to compact feces

-Water and electrolytes are absorbed

-Bacteria (microbiota) break down undigested fiber and produce vitamin K, some B vitamins and lipids
Term
What is a Inflammatory bowel disease (IBD)?
Definition
-Chronic conditions such as ulcerative colitis and Crohn’s disease that cause inflammation of the lower GI tract
Term
What is Irritable bowel syndrome (IBS)?
Definition
Condition of the lower GI tract that causes abdominal pain, muscle spasms, diarrhea, and constipation
Term
What under voluntary control, controls waste elimination?
Definition
-The external anal sphincter
Term
Whats the function of Endogenous Flora?
Definition
-bacteria that live in the nooks of the LI (take up space)
-protect against infection
-development of immune system
-manufacture nutrients: Vit. K. - not produced by the body - blood wont clot without it
Term
What causes the appendix to burst?
Definition
- Endogous flora can sometimes become "unfriendly"
Term
What is in yogurt that replace these EF bacteria?
Definition
-Acidophilus cultures that colonize in the LI
Term
What is a polyp?
Definition
A normal cell that goes cancerous then grows into a tumor...takes 5 mutations in DNA of cell
Term
What hormones simulate and reduce hunger?
Definition
-Ghrelin
-Leptin
Term
What enzyme in the gastic juice are required for protein breakdown ?
Definition
-pepsin
Term
What is produced in the baser of the pits and are released into the blood stream?
Definition
gastrin
Term
What is the enzyme that breaks down strach?
Definition
-Amylase
-hydrolyses by adding water across the bonds of the polymer glucose (many as 3000)
-speeds up this breakage
-30% of the population have it
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