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Definition
chemical that destroys bacteria EXCEPT those in endospore stage |
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chemical that kill fungal spores, hyphae, and yeasts |
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chemical known to inactive viruses, especially on living tissue |
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agent capable of destroying BACTERIAL endospores |
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Definition
chemical agent that kills PATHOGENIC microorganisms
used on inanimate and living tissue |
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Definition
use of physical process OR chemical agent to destroy VEGETATIVE PATHOGENS but NOT bacterial endospores
also removes TOXINS |
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Which process only works for inanimate objects? |
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Definition
disinfection
Ex: bleach, boiling, iodine solution |
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Definition
growth of microorganisms in the BLOOD or other TISSUES |
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Definition
practice that prevents entry of infectious agents into STERILE tissues --> prevents infection |
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Definition
CHEMICAL AGENTS applied directly to exposed body surfaces to destroy/inhibit VEGETATIVE PATHOGENS
Ex: iodophors, antibacterial soap, chlorhexidene |
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Definition
cleansing technique that removes microorganisms from INANIMATE surfaces
Ex: dishwashing, laundering clothes |
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Definition
cleansing technique that removes microorganisms from LIVING TISSUE
Ex: alcohol wipes, surgical hand scrub |
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Describe how surfactants work as microbial agents |
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Definition
They are nonselective and cidal
- They lower the SURFACE TENSION of cell membranes
- These polar molecules bind to the lipid layer and penetrate the internal hydrophobic region
- Leave "leaky spots"
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What are the 3 factors that must be considered before an actual antimicrobial therapy? |
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Definition
- Nature of infecting microorganism
- Degree of microorganisms sensitivity to drugs
- Overall medical condition of patient
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What could be examined as a way of rapid initial method for detecting the agent? |
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Definition
examine body fluids, sputum, or stool |
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Term
Penicillin is prescribed to fight: |
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Definition
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What is the leading cause of meningitis in children? |
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Definition
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What is the second leading cause of meningitis in children? |
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Definition
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3 Reasons why antimicrobial treatments fail: |
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Definition
- Drug cant diffuse into body compartment
- Unnoticed resistant cells
- Infection caused by more than one pathogen
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Term
3 factors that influence choice on drug |
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Definition
- Nature & spectrum of drug
- Potential adverse effects
- Condition of patient
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Term
As a final drug selection, it is best to choose: |
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Definition
narrowest-spectrum drug since it decreases super infections and other adverse reactions |
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Term
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Definition
ratio of drug dose that is toxic to humans compared to its minimum effective (therapeutic) dose |
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In take of other drugs: increases nephrotoxic effects |
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Definition
aminoglycides & cephalosporins |
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In take other drugs: decrease absorption of isoniazid |
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Definition
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Term
In take other drugs: these 2 antibiotics with oral contraceptives can take away its effectiveness |
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Definition
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What are the 3 antiviral mode of actions? |
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Definition
- prevent penetration of virus into host
- block replication, transcription, translation of viral material
- prevent natural maturation of viral particles
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Term
What drugs only treat Influenza A? |
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Definition
Amantadine and RImantidine |
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Term
what do the drugs treating influenza A block? |
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Definition
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Term
What drugs treat Influenza A and B? |
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Definition
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Term
What do the drugs for Influenza A and B block? |
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Definition
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Term
What are compounds related to Acyclovir? |
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Definition
- valacyclovir (VALTREX)
- famiciclovir (FAMVIR)
- peniciclovir (DENAVIR)
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Term
What was used to treat cytomegalovirus infections in immunocompromised? |
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Definition
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Term
What enzyme is used by viruses to process nucleosides? |
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Definition
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Term
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Definition
virus that carries genetic info in the form of RNA
HIV and AIDS |
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Term
RNA genome is used as a template by which enzyme to produce a DNA copy of the genetic info? |
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Definition
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What interferes with the synthesis of a new DNA strand |
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Definition
Nucleoside Reverse transcriptase inhibitors |
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Term
What virus infects the respiratory tract and produces giant multinucleated cells |
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Definition
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What are the treatments for pneumovirus (RSV) |
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