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Exam 2 Micro
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76
Biology
Undergraduate 2
02/28/2010

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Term
Cryptosporidium Parvum
Definition
Immunocompetent or immunocompromised.
DX: oocysts in sample
Term
Rotavirus
Definition
dehydration, peaks in winter, and new vaccine for kids (RotaTeq), and wheel shaped "rota"
Term
Norovirus
Definition
Projectile vomiting and watery diarrhea, Airborne transmission, get on cruise ships, and shaped like a "calici" or cup
Term
Adenovirus
Definition
dsDNA, "sputnik virus" shape, Gastroenteritis- serotypes 40,41,42
Term
Acute Diarrhea with Vomiting
Definition
preformed toxin, intoxication NOT infection
Term
Staph Aureus Exotoxin
Definition
Staph enterogtoxin= VF, food that has been left out for too long
Term
Bacillus Cereus
Definition
"Fried Rice", Two exotoxins one cause diarrhea and one cause vomitting
Term
Giardia
Definition
flatulence with greasy, malodorous stool. Get it from WATER. "Beaver Fever", recognized with parasite with TWO eyespots
Term
Entamoeba histolytica
Definition
Bloody diarrhea, also called Non-Bacillary dysentery, Most common target is the liver, and transmission of CYSTS and replicates as trophozoites
Term
Viral Hepatitis
Definition
inflammation of the liver, Symptoms include Jaundice and dark tea colored urine
Term
Hepatitis B Virus
Definition
may cause chronic hepatitis leading to cirrhosis or cancer, Its a PROCESS, Hep to cirrhosis to cancer, BALL AND STICK appearance, has LATENCY
Term
Hep C virus
Definition
transmitted via body fluids, same as B but ten times worse, RNA and DNA and then can tell difference between C and B
Term
Helminthic Intestinal Infections
Definition
S&S varies but involve GI issues, VF= Mechanical blockage and tissue damage, DX= discover eggs, larvae, or adult worms in stool
Term
Oral Infections
Definition
normal biota biofilm damages teh soft tissues and cones surrounding the teeth, Strep mutans are involved
Term
Periodontal Disease
Definition
Gingivitis occurs which is the swelling of normal contour, patches of redness, and increased bleeding of the gingival
Term
Necrotizing Ulcerative Gingivitis
Definition
"trench mouth", severe pain, bleeding in mouth,
Term
Mumps
Definition
Parotitis happens and VF= syncytia forms which is cells fusing together
Term
Gastritis or Gastric ulcers
Definition
Gastric Carcinoma (stomach cancer) forms, VF=Urease enzymes, breathe out ammonia if have this
Term
Intestinal Mucosa
Definition
Disruption or killing these cells by pathogens results in malabsorption and diarrhea, two main cells types: ENTEROCYTES and CRYPT
Term
Acute Diarrhea
Definition
Reiter's syndrom= can't see, can't pee, can't climb a tree
Guillain Barre Syndrome=peripheral neuropathy ( lost function, stop moving well)
* Bacteria, viral, and parasites cause this
Term
Salmonella
Definition
Diarrhea, cause SHOCK if gets in bloodstream, infects bones (osteomyelitis), Typhoid Fever can happen caused by LPS, VF=INVASIVE
Term
Shigella
Definition
severe bloody stools ( dysentery), can lead to ulcerative colitis and HUS, VF=SHIGA TOXINS, fecal-oral spread!!
Term
EHEC
Definition
E.coli O157, causes bloody diarrhea, uses SHIGA TOXIN, can lead to HUS, get it from undercooked meat!
Term
ETEC
Definition
watery diarrhea (Traveler's diarrhea), Uses two toxins (ST and LT)
Term
EPEC
Definition
infants and toddlers get it, causes intestinal cell membranne to rearrange by DEPOLYMERIZING into Pedestal formations
Term
EIEC
Definition
Invades!!! causes bloody diarrhea, DX: only lactose negative e.coli
Term
EAEC
Definition
Chronic diarrhea in young children
Term
Campylobacter jejuni
Definition
#1 mose common bacterial cause of diarrhea in US. VF= 2 toxins:enterotoxin and crytotoxin, ASSOCIATED with cooked chicken
Term
C. Diff
Definition
Major cause of diarrhea in the hospitals, destruction of cell wall (pseudomembranous colitis), VF= two enterotoxins( toxin A and B) and produce SPORES!!!
Term
Vibrio chloerae
Definition
"Rice Water" aka watery diarrhea, DEHYDRATION is most serious issue, FECAL_ORAL via water!! VF= Cholera toxin, and gram stain is comma-shaped bacterium
Term
UTI's
Definition
start as urethritis with painful, burning urination, and reduced urine flow. VF=urease enzymes, Introduction of bacteria in bladder( CYSTITIS)
affects arteries (pyelonephritis)
Term
E.coli (UTI)
Definition
DX by clean catch urine sample, caused by UPEC, VF=P-pili (needs to stick)
Term
Proteus species
Definition
UTI with kidney stone formation, VF=highly motile, potent urease, use INDOLE TEST to determine cause, Red ring=positive for indole
Term
Staphylococcus saprophyticus
Definition
UTI common in sexually active females, VF=none known, Use novobiocin to identify
Term
Vaginitis(candida albicans)
Definition
caused by candida albicans, inflammed vagina, buring and itching, DX= oral thrush,diaper rash, and nosocomial infections, GROWTH includes white colonies, "egg shaped" budding yeast, and GERM TUBE when incubated in serum
Term
3 categories of Sextually transmitted diseases
Definition
1. discharge disease
2. ulcer diseases
3. wart diseases
Term
Vaginosis (Garnerella vaginalis)
Definition
infection but no inflammation, itching and fishy odeor vagina, grey or yellow discharge, DX= vaginal smear with "clue catch"
Term
Vaginosis (Trichomonas vaginalis)
Definition
causes gree white, FROTHY, foul smelling vaginal discharge, very bubbly!!, caused by parasites! "Strawberry cervix"
Term
Prostatis
Definition
for men!, inflammation of prostate glands, caused by GI flora,
Term
Gonorrhea
Definition
painful urination, yellowish discharge(male), bloody vaginal discharge (female) Major complications as infection ascends, Caused by N.gon, ID= uses glucose only "g=g"
Term
Gonorrhea
Definition
2nd most common std in world, very high increase in adolescents, asymptomatic carriage greater in women but disease found more in men, arthritis is an outcome of this disease! PID!!!!
Term
Chlamydia
Definition
no symptoms(asymptomatic), watery discharge, caused by serotypes D-K, VF=obligate, ID= bi-phasic life cycle(look at notes!!)
Term
Chlamydia
Definition
most common infectious disease, Pinkeye is cause by serotypes A,B,&C, LOOOK AT NOTES
Term
Ureoplasma urealyticum (NGU-2)
Definition
if rule out chlamydia and gonnorrhea then you have this!!!, VF=Urease enzymes, light discharge and burns when pee.
Term
Genital Ulcer Diseases
Definition
Syphilis, chancroid, and genital herpes
Term
Treponema pallidum(Syphilis)
Definition
LOTS of S&S!, goes thru 3 distinct stages, caused by spirochete!, ID= will not gram stain so GIEMSA is used!
Term
Stage 1- Primary Syphilis
Definition
hard chancre at site of infection, Painless ulcerated erosion, HIGHLY INFECTIOUS!
Term
Stage 2-Secondary stage
Definition
get skin rash, mucous patches, joint pain,hair loss, and condyloma lata(warts near chancre sites)
Term
Stage 3-Teritary Syphilis
Definition
occurs in half of untreated patients, get gummas lesions, Necrotic palate on tounge, CNS involvement, "attacks your nuts and then you go nuts..!"
Term
congenital syphilis
Definition
transmission from mother to child, usual ends in STILL BIRTHS!
Term
Syphilis Treatment
Definition
RPR test! uses extract of beef heart
Term
Genital Herpes
Definition
no symptoms, mulitiple vesicles on genitalia(painful), can go latent and pop back up, VF=viral, has two types!
Term
Type 1 (herpes)
Definition
mouth sores
Term
Type 2- Herpes
Definition
vaginal/ penis area
Term
Wart diseases
Definition
most common STD in world, do not have to report, CAused by HPV!! 53 antigenically distinct types!
Term
Pathogenesis
Definition
warts are benign, ID=koliocytosis(HPV) LOOK AT NOTES
Term
metabolism
Definition
all chemical reactions and physical workings of the cell to either gain or use energy
Term
anabolism
Definition
also called biosysthesis, any process that results in synthesis of cell molecules and structures (usually requires energy input)
Term
Catabolism
Definition
breakdown of bonds of larger molecules into smaller molecules (RELEASE ENERGY) big to little!
Term
Enzymes
Definition
protein biological catalysts that increase the rate of a chemical reaction without becoming part of the products or being consumed in the reaction!
Term
Exoenzymes
Definition
break don molecules outside of the cell
Term
Endoenzymes
Definition
break down molecules inside of cell in cytoplasm
Term
Constitutive enzyems
Definition
always present and in relatively constant amts ( always on!!!)
ex: breaking down glucose
Term
Regulated enzymes
Definition
production is either induved or repressed in response to change (on or off depending on what doing!!)
Term
HPV 6,11
Definition
most common, genital warts and condylomata acuminata(elevated lesions, "cauliflower like" lesions
Term
HPV 16,18
Definition
Carcinoma of the cervix,penis, warts turn cancerous!!!! very nasty!
Term
HPV 1-4
Definition
not for genitals, but are SKIN and PLANTAR WARTS!!!
Term
Pathogenesis(warts)
Definition
P53 and RB are proteins that inactivate therefore turn malignant, ID=koilocytosis
Term
Gram - (staining)
Definition
pink stain
Term
Gram + (staining)
Definition
purple stain
Term
Enterobius vermicularis (PINWORM)
Definition
the butthole worm!, causes itching and squirming, crawl out and lay eggs
Term
Ascaris lumbricoides(Roundworm)
Definition
intestinal worm, eggs consumed from enviorment
Term
Necator americanus(Hookworm)
Definition
tissue worm, causes severe nutrient depletion, and failure to thrive
Term
Trichinella spiralis(Hunter's worm)
Definition
likes wild game:beer, boar, deer. COOK YOUR MEAT!! forms cysts in muscle and brain
Term
Taenia saginata(BEEF TAPEWORM)
Definition
form by undercooked BEEF! recognized by scolex with suckers only
Term
Taenia solium( PORK TAPEWORM)
Definition
from undercooked pork, auto-infection cycle(will keep going), causes cysts, recognized by scolex with suckers AND TEETH!
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