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Exam 1 OTC Cough and cold
cough
35
Pharmacology
Professional
09/17/2012

Additional Pharmacology Flashcards

 


 

Cards

Term
Productive cough. Clear secretions
Definition
Bronchitis
Term
Productive Cough. Purulent secretions
Definition
Bacterial Infection
Term
Productive cough. Discolored Secretion
Definition
Yellow with inflammatory disorder
Term
Productive cough. malodorous secretion
Definition
anaerobic bacterial infection
Term
Nonproductive cough Causes (5)
Definition

-Viral respiratory infection

-atypical bacterial infection

-GERD

-Cardiac disease

-Medications

Term
Pharmacologic action of Antitussives
Definition
Suppresses the cough
Term
Action of expectorants
Definition
Loosens the mucus
Term
 Dextromethorphan Dose
Definition
Adult: 30 mg PO every 6 to 8 hours
Children (age 6-12): 15 mg every 6 to 8 hours
Children (age 2-6): 7.5 mg every 6 to 8 hours
Term
Adverse Effects of Dextromethorphan
Definition
—Confusion
—Excitation
—Nervousness
—Irritability
—Abuse potential
Term
Acute Cough
Definition

-duration less than 3 weeks

-commonly caused by upper respiratory infection

Term
Sub-acute cough
Definition

-Duration of 3-8 weeks

-Commonly caused by bacterial sinusitis, asthma, or infection

Term
Chronic cough
Definition

-Duration of longer than 8 weeks

-commonly caused by postnasal drip syndrome (PNDS), asthma, and GERD

Term
Topical Antitussive MOA
Definition

-Stimulate sensory nerve ending withing the nose and mucosa

-Creates a local anesthetic sensation and a sense of improved airflow

Term
Dextromethorphan AE
Definition
confusion, excitation, nervousness, irritability, abuse potential
Term
Dextromethorphan contraindications 
Definition

-hypersensitivity rxn

-MAOI use in 14 days

Term
Expectorant (Guafensin) MOA
Definition

-Loosens and thins lower respiratory tract secretions

-Makes cough more productive

Term
Expectorant (Guaifenisen) Dose
Definition
—Adult: 200-400 mg PO every 4 hours
—Children (age 6-12): 100-200mg mg every 4 hours
—Children (age 2-6): 50-100 mg every 4 hours
Term
Diabatic Tussin
Definition

-Free from sugar

-Free from alcohol

-Free from salt

Term
Triaminic thin strips Directions
Definition
—Dose (age 6 to 12 years): Dissolve 2 strips on tongue.    May be taken 6 to 8 hours
—Do NOT exceed 8 strips in 24 hours or as directed               by a physician
—Children (under 6 years): Ask the physician
Term
Most common recommended cough drops
Definition

-Vicks

-Robutussin

-Dimetapp Cold

-Theraflu

-Pediacare

Term
Who should not treat?
Definition

-should not treat fever for more than 3 days without referral for evaluation

-thick yellowish green phlegm

-drenching night time sweats

-cough for more than 1 week despite OTC medications

-drug related

-Chronic underlying disease (congestive heart failure, GERD, cancer)

Term
Epidemology (Viral infection of the URT)
Definition
—One of the top  diagnosed illnesses in the US
—62 million cases annually
—Children have 6-10 colds per year
—52 million under the age of 17
—Women (ages 20-30) > Men
—Patients spend ~ $299 million on OTC products annually
Term
Etiology of cold (Viruses)
Definition
—> 200 different viruses
—Rhinovirus
—Respiratory syncytial virus (RSV)
—Coronaviruses
—Coxsackie viruses
—Influenza viruses
—Parainfluenza viruses
—Adenoviruses
Term
Appears 1-3 days after cold infection
Definition
—Sore throat – 1st to appear
—Runny nose – dominate by 2 or 3 days
—Congestion
—Sneezing
—Weakened senses of taste and smell
—Cough - < 20% on day 4 or 5
—Low grade fever (infants and young children)
Term
Vicks VapoRub directions
Definition
—Temporary relieve on chest and throat, cough, and nasal congestion
—Rub a thick layer on chest and throat. Repeat up to 3 times a day
Term
Vicks Baby Rub  (Vaporizing Cream for children)
Definition
—Can be used for children 3 months and older
—Gently massage on neck, chest, and back
—Avoid eye contact
—Do NOT heat
—Do NOT use in mouth or nostrils
—DO NOT use on face
Term
MOA of Decongestants
Definition
—Stimulate adrenergic receptors
—Decreases blood supply in sinusoid vessels in the nose and decreases mucosal edema
—Non-selective
Term
Short Acting nasal decongestants
Definition

(4 to 6 hours)

-Phenylephrine

-Tetrahydrolizine

Term
intermediate acting
Definition

(8 to 10 hours)

-Xylometaziline

Term
Nasal Spray Products
Definition
Afrin, Neo-Synephrine, vicks sinex, distan 12 hr nasal, little noses decongestant nose drops
Term
Decongestant Side Effects (Oral)
Definition
—Elevated blood pressure
—Increase heart rate
—Palpitation
—Restlessness, insomnia, anxiety, tremor
Term
Decongestant Side Effects (Nasal)
Definition
—Minimally absorbed
—Local irritation
—Rhinitis medicamentosa
Term
Effective Herbal cold Remedies
Definition

-Echinacea

-Zinc Lozenges

Term
Special Populations (Use during pregnancy and lactation)
Definition

-Avoid extra-strength, long acting or combination products, 

-Topical decongestants (Oxymetazoline-safe during pregnancy ,Phenylephrine-safe in nursing mothers)

-Systemic Decongestants (Psuedophedrine-safe in nursing mothers)

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