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exam 1
exam 1
104
Biology
Undergraduate 1
01/28/2011

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Term
WHat are the lowest level of organization that can perform all activities required for life.
Definition
Cells
Term
Cells contain the heritable information in the form of:
Definition
DNA
Term
Whats the difference between reductionism and using discovery based science.
Definition

reductionism involves reducing complex systems to simpler components as a way to understand how the system works.

Discovery based science is the collection and analysis of data without the need for a preconcieved hypothesis

Term
The 3 domains of life are:
Definition
bacteria, archaea and eukarya
Term
Taxonomy
Definition

grouping of species

-based on evolutionary history

Term
What is the difference between evolution and natural selection?
Definition

Evolution describes a heritable change in one or more charecteristics of a population from one generation to the next

Natural Selection: individuals with heritable traits that make them better suited to thier enviorment  tend to flourish.

Term
What is the evidence for evolution?
Definition
 fossil record, biogeography
Term
What is meant by a structure/function relationship?
Definition
How specific molecules, organelles, cells, tissues, organs, and body structures are structured to support the functions that they perform
Term
What is the difference between vertical evolution and horizontal gene transfer?
Definition

Vertical: new species evolve from pre-existing species by the accumalation of mutations

 

Horizontal: organism incorperates genetic material from another organism without being an offspring of that organism

Term
A genome is
Definition
the total genetic composition of a species.
Term
A proteome is 
Definition
 the collection of proteins made
by a given cells.
Term
What is the heart of science?
Definition
Inquiry, or the desire to know
Term
  What is the logic of discovery science and is often based on qualitative data?
Definition
Inductive reasoning (observations)
Term
What is the logic of hypothesis science and is often based on quantitative data?
Definition
Deductive reasoning (numbers)
Term
What is a tenatitve answer to a well-framed question?
Definition
Hypothesis
Term
A hypothesis must be:
Definition
testable and must be falsifiable.
Term
What is a broad explanation of some aspect of nature that is backed up by observation and data?
Definition
A theory
Term

How many atoms make up a molecule?

 

 

Definition

2 or more atoms make up a molecule

 

Term
Matter consists of chemical elements in pure form and in combinations called:
Definition
Compounds
Term
Compounds have 2 or more DIFFERENT:
Definition
Elements
Term
Life requires about 25 chemical elements. Which 4 make up most of our cells?
Definition
oxygen, carbon, hydrogen, nitrogen
Term
Structure of the atom determines:
Definition
the behavior of an element - Neutrons, Protons, Electrons.
Term
Atomic Number =
Definition

# of protons

= # of electrons if neutrally charged element.

Term
Atomic mass =
Definition
#neutrons + # protons.
Term
What is Avogadro’s number?
Definition
6.022 x 10^23
Term
Isotopes differ:
Definition
only in the number of neutrons
Term
Electrons dictate:
Definition
the chemical behavior of the element.
Term
The outer electron shell is called
Definition
The valence shell, It contains valence electrons. The number of valence electrons determines an atom’s chemical bonding properties.
Term
 A covalent, non-polar bond is formed when
Definition

 atoms share electrons equally

(Ex: c-h)

Term
 a covalent polar bond is formed when
Definition

one atom of a pair has the shared electrons more often than the other

(Ex: water)

Term
 an ionic bond is formed when
Definition

0ne atom of a pair basically steals the electrons of the other atom, transfer of electrons

(Ex: salts)

Term
How can you determine if a bond or molecule is polar?
Definition

 if one side is a bit more electronegative so the electrons hover in that area more



Term
Molecular shapes of molecules
Definition
are related to their functions. Molecules are not rigid.
Term
The making and breaking of chemical bonds is called
Definition
chemical reactions
Term
A solution is a
Definition
homogeneous mixture of 2 or more substances.
Term
Aqueous solutions use
Definition
water as the solvent.
Term
Water dissolves
Definition
polar molecules easily-hydrophyllic molecules
Term
Nonpolar molecules such as
Definition
oils are hydrophobic and not dissolved in water
Term
Water molecules can dissociate into H+ and OH- ions. What are these called?
Definition
Acids and Bases
Term
Acids add
Definition
H+ ions to solution
Term
bases:
Definition
subtract H+ from solution.
Term
A measure of H+ concentration, [H+], is
Definition
pH.
Term
A pH lower than 7 is ______, a pH greater than 7 is ______
Definition

acidic

alkaline or basic

Term
Each pH unit represents
Definition
a ten-fold difference in ion concentration.
Term

Buffers are...

 

Definition

substances that resist change in pH.

 

 

 

Term
Organic chemistry is
Definition
chemistry of carbon based compounds.
Term
Essential molecules of life:
Definition
Proteins, DNA Sugars, Fats,
Term
Carbon has _____ in the valence shell (the outer shell) and so can form _______ with
other atoms - it can make a vast array of molecules.
Definition

4 electrons

4 covalent bonds

Term
Hydrocarbons (carbon+hydrogen) are
Definition
the simplest organic molecules.
Term
Isomers are molecules with
Definition
 same molecular formula by different structural arrangements.
Term
Structural isomers -
Definition
differ in arrangement of atoms and often in location of double bonds.
Term
Geometric isomers -
Definition
differ in structure due to inflexibility of double bonds.
Term
Enantiomers -
Definition
mirror image isomers
Term
Hydroxyl group
Definition
(-OH)
Term
Carbonyl groups
Definition
(-C=O)
Term
Carboxyl groups
Definition
(-COOH)
Term
Amino groups
Definition

(-NH2)

when with COOH its a amino acid

Term
Sulfhydryl goups
Definition
(-SH)
Term
Methyl group
Definition
(-CH3)
Term
Four kinds of macromolecules are found in living organisms:
Definition
Carbohydrates, Lipids, Proteins, and
Nucleic Acids.
Term
Polymers are
Definition
large molecules formed by linking many similar smaller molecules called MONOMERS
together. Think beads on a string.
Term
Most macromolecules are formed by 
Definition
 dehydration (condensation) synthesis. One monomer looses an -H and the other an -OH to form water, and the monomers end up covalently bonded.
Term
Hydrolysis (Lysis by water) is
Definition
the breaking of monomer-monomer bonds.
Term
MONOSACCHARIDES are
Definition
the simpliest sugars (single sugars)
Term
Polysaccharides are made of
Definition
monosaccharide monomers joined together.
Term
Lipids -
Definition
insoluble in water (Fats, phospholipids, steroids).
Term
Fatty acid =
Definition
carbon chain with carboxyl group at the end.
Term
Fat =
Definition
fatty acids linked to a glycerol molecule by an ester bond.
Term

Phospholipid = 

What are they used for?

Definition

glycerol + 2 fatty acids + phosphate group.

they make up the structure  of cellular membranes

Term
Steroids =
Definition
4 fused carbon rings
Term
what is the difference between estrogen and testosterone?
Definition
estrogen has one less methyl group, a hydroxyl group instead of a keytone group and addtional double bonds in one of its rings
Term
Proteins -
Definition
polymer of amino acids
Term
What are some functions of proteins?
Definition
 communications, structure, initiate movment, catalyzing reactions through enzymes
Term
Amino acids are linked by
Definition
peptide bonds
Term
what is a folded polypeptide with a function?
Definition
protien
Term
Primary structure =
Definition
amino acid sequence
Term
Secondary structure =
Definition
twisting or folding of primary sequence into - alpha-helix, beta pleated
sheet or random coil
Term
Tertiary structure =
Definition
- folding of secondary structure
Term
Quaternary structure =
Definition
more than one polypeptide chain
Term
Why is quaternary structure important in protein-protein interactions?
Definition
it makes the protien functional, important in building cellular structure that provide shape and organization to cells
Term
How can a change of one amino acid affect protein function?
Definition
it can change the structure from one protien to another
Term
Nucleotide =
Definition
pentose sugar +phosphate group + nitrogenous base.
Term
Nitrogenous Bases -
Definition

Pyrimidines (6 membered rings) - Cytosine C, Thymine T, Uaicil U

Purines ((6 membered ring +5 membered ring) Adenine A, Guanine G
Term
Pentose Sugar -
Definition

RNA- ribose

DNA - deoxyribose
Term
What are joined by phosphodiester linkages to form a polymer (RNA or DNA)
Definition
Nucleotides
Term
What form the backbone and nitrogenous bases extend from that backbone.
Definition
Sugar and phosphate
Term
Hydrogen bonds between bases form
Definition
double helix
Term
The order of what constitutes information storage in biological systems?
Definition
nitrogenous bases
Term
Cell theory:
Definition
• All living things are composed of one or more cells
• Cells are the smallest units of living organisms
• New cells come only from pre-existing cells by cell division
Term
Prokaryotic cells:
Definition
Simple cell structure, lack a membrane-enclosed nucleus
• 2 categories- bacteria and archaea
Term
Plasma membrane-
Definition
barrier
Term
Cytoplasm-
Definition
site of metabolism
Term
Nucleoid-
Definition
region where genetic material found
Term
Ribosomes-
Definition
involved in protein synthesis
Term
Glycocalyx-
Definition
traps water, protection
Term
Appendages-
Definition
pilli (attachment), flagella (locomotion)
Term
Eukaryotic cells:
Definition
• Are more complex: DNA housed inside nucleus, contain organelles/compartmentalized
Term
Cytosol
Definition
• Outside the cell organelles but inside the plasma membrane
• Function: metabolic activities of eukaryotic cells, where polypeptide synthesis (Translation) occurs
Term
Cytoskeleton
Definition
protien filaments that provide shape and aid in movement
Term
Motor Proteins
Definition
 Use ATP as a source of energy
Three different kinds of movements
-moving cargo from one location to another
-moving filament
both the motor protein and filament restricted in their -movement to exert a force that causes the
filament to bend (Flagella and cilia)
Term
What are the characteristics of flagella and cilia? What is their structure?
Definition

-flagella is longer than cilia

-cilia tend to cover all or part of the surface of the cell

-they both share the same structure called the axoneme

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