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Exam 1
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214
Microbiology
Undergraduate 3
03/05/2015

Additional Microbiology Flashcards

 


 

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Term
What does the host provide to the parasite?
Definition
1. Space to live
2. Food
3. Protection
Term
Homogenetic
Definition
Relationship between 2 individuals ain the same species
Term
Heterogenetic
Definition
Relationship between 2 individuals of different species
Term
Competition
Definition
2 species compete for same resources
Term
Predation
Definition
One species kills and eats another
Term
Symbiotic
Definition
2 organisms living in close association
Term
Symbiosis includes
Definition
Phoresis
Commensalism
Parasitism
Mutalism
Term
Phoresis
Definition
2 symbiants traveling together
Term
Commensalism
Definition
1 symbiant benefits and the other is unaffected
Term
Parasitism
Definition
1 symbiant benefits and the other is negatively affected
Term
Mutalism
Definition
Both symbiants benefit
Term
Animal parasites are found in 3 goups
Definition
Protozoa (Unicellular)
Helminths (Worms)
Arthropoda
Term
Helminths (worms) include
Definition
Nematoda (Roundworms)
Trematoda (Flukes)
Cestoda (Tapeworms)
Term
Platyhelminths (Dorso-ventrally flat)
Definition
Trematoda and Cestoda
Term
Invasion
Definition
1 organism gains access to the surface or internal tissues of another (little or no increase in numbers)
Term
Infestation
Definition
1 organism gains access to the surface or tissues of another and small increase in numbers (Small = 10-dozens)
Term
Infection
Definition
1 organism gains access to the surface or tissues of another and a huge (100's-millions) increase in numbers
Term
While a predator may participate in destructive consumption a parasite feeds by
Definition
Cropping (Eating little by little)
Term
While the nutrition provided by the victim is the whole body or selected tissues for predators, it is ____ for parasites
Definition
Fragments, fluids, etc
Term
While a predator may be lethal to its victim
Definition
A parasite is rarely lethal
Term
While a predator may coexist with its prey, a parasite may live
Definition
In or on its host
Term
While a predator may be large or strong, a parasite is usually
Definition
Smaller or much smaller
Term
Fewer predators than
Definition
Parasites
Term
While a predator may come in contact with its prey momentarily, a parasite
Definition
Comes in contact with its prey for a prolonged and/ or repeated amount of time
Term
While a predator may "herd" for protection, a parasite
Definition
Will not herd
Term
While a predator usually won't cause disease unless its related to stress, a parasite
Definition
Will often cause direct disease
Term
Life cycle of Entamoeba histolytica
Definition
1. Person ingests cyst in contaminated food or water
2. Travels to Ileum and excysts
3. Divides via binary fission and matures to Trop stage
4. Matures in mucosal crypts
Term
Amoebic dysentery
Definition
Entamoeba histolytica dissolves mucosa to get at RBC's in capillaries for oxygen which causes the host irritation
Term
Pathophysioogy of an entamoeba histolytica infection
Definition
Mucosal infiltrate
Ulceration in the cecum
Gall Bladder-like symptoms
Small flask ulcerations
Rare- Affects the heart and lungs
Very rare- Amoebic lung excess and histolysis of brain tissue
Term
Three stages of Entamoeba histolytica infection
Definition
1. Noninvasive colonization
2. Intestinal disease (Diarrhea, dysentary)
3. Extra intestinal colonization (Break out to any other place in the body)
Term
Excystation of Enatamoeba histolytica occurs
Definition
Outside the body
Term
Trophozoite form of Enatamoeba histolytica occurs
Definition
Inside the body
Term
Metacyst of Enatamoeba histolytica occurs
Definition
Inside the ilium before the troph stage
Term
Granulomatous amebic encephalitis (GAE)signs and symptoms include
Definition
Headaches
Stiff neck
Nausea
Vomitting
tiredness
Term
GAE causative organism
Definition
Acathamoeba spp
Term
GAE begins when
Definition
Organism enters via lungs and spreads to CNS. Slow and chronic onset that is mostly found in ICP's
Term
What may be found in patients with GAE?
Definition
Trophs found in CSF or brain plus cysts in the brain
Term
Amebic keratitis (AK)
Definition
Disorder of the eyes produced by off-label (prolonged) use of disposable contact lenses
Term
Risk factors of AK include
Definition
Corneal foreign body
Contact with non-sterile water
Neurotrophic keratopathy
Herples simplex karatits
Radial kertomy
Off-label contact lens use
Term
Patients with AK present with
Definition
Term
Giardia lamblia
Definition
First discovered in 1681 by Leeuwenjoek in his stool. Called it pissabed
1859 Vilem Lambl calle it cercomonas intestinalis
1879 Kuntsler found giardia like organism and called it Giardia agilis
1915 Stiles found Giardia lamblia
Term
Giardia lamblia patho
Definition
Infects the upper respiratory tract and may penetrate to liver and gall bladder. May cause irritation to mucosal lining. May need 5 or 6 stool specimen
Term
Giardia lamblia life cycle (Takes 6-8 hours)
Definition
1. Person eats cyst
2. Excyst in the duodenu and divides via binary fission
3. Recyst before it reaches the rectum
Term
Giardia lamblia cyst
Definition
Has up to 4 nuclei.
Term
Giardia lamblia symptoms
Definition
Mild diarrhea, anorexia, flatulence, decrease serum protein, gamma globulin, folic acid and fat soluble vitamins
Term
Chilomastix mesnili
Definition
Non pathogen. Cyst looks like lemon drop.
Term
Trichamonas hominis
Definition
Only intestinal flagellate with no cyst. Non pathogen
Term
Trichamonas vaginalis
Definition
Found in the Gentro-urinary tract (Similar to trich. hominis) causes vaginal discharge, burning, itching in female. Often aymptomatic in males
Term
Best specimen for trich vaginalis
Definition
Urethral, vaginal, prostate, urine. Should be collected warm in 2-3% glucose with 0.87% Nacl
Term
Trichamonas tenax. (Trich buccalis)
Definition
Found in the tarter of teeth in the pyorrheal pockets and tonsilar crypts
Term
Trichamonas tenax spread via
Definition
Shared contaminated dished, drinking glasses, respiratory pathogen
Term
Enterobius hominis
Definition
Rare, tropical and temperate areas, not a pathogen
Term
Retortamonas intestinalis (also called Embadomonas spp)
Definition
Not common, only seen in tropical and temperate regions. Troph small with 2 anterior flagella and cytosome near nucleus
Term
Retortamonas intestinalis cyst
Definition
Smaller then troph has 1 large nucleolus. Contains "Bird's Beak fibrils" (piece left over from troph form)
Term
Dientamoeba fragilis
Definition
Cosmopolitan organism. Very resistant, possible pathogen. Considered ameboflagellate. Can live in mucosal crypts, ingest rbc's. Found in most mental health facilities and pediatric populations
Term
Dientamoeba fragilis symptoms
Definition
Diarrhea, abdominal pain, nausea, anorexia, vomiting, fatigue
Term
Intestinal cilliates
Definition
Balantidium coli
Term
Balantidium coli
Definition
Found in tropical and temperatre regions, common in hogs and monkeys. Found in the lg intestine and cecum, eat bacteria, ingress organism
Term
Balandtidium coli troph
Definition
Covered with cilia
Term
Balantidium coli life cycle
Definition
1. person eats it
2. excysts
3. Divides
4. Feeds on mucosal crypts
5.Encysts
5. Shit out
Term
Balantidium coli patho
Definition
Patients are asymptomatic or may have severe dysentary for weeks to months. Can penetrate tissue. Produces hyaluronidase
Term
Malaria related organisms (Falciparum organisms) are in the order and class
Definition
Eucoccidiida
Term
80% of all Malaria cases are caused by the organism.
Definition
Plasmodium vivax.
Term
15% of all Malaria cases are caused by the organism
Definition
Plasmodium falciparum
Term
Where did malaria parasites originate?
Definition
Africa and fossils of mosquitos
Term
What are the vectors for Malaria?
Definition
Anopheles spp. mosquitos
Term
What is the most pathogenic species of plasmodium?
Definition
Falciparum
Term
Plasmodium life cycle (Exoerythytic shigonomy portion)
Definition
1. Take bloodmeal from person and inject infective stage sporozoites into another human via the capillaries in the human peripheral CVS
2. Escape to liver within 40 mins
3. Invade pharyngeal cell
Term
Plasmodium life cycle after exoerythytic shigonomy
Definition
1. Development continues to mature EES schizont
2. Once mature schizont ruptures, releasing merozoites into the blood that enter gametocytosis in the peripheral blood
Term
Merozoites have apex (front ends) and are said to be
Definition
Apicomplexical organisms
Term
Plasmodium escapes via
Definition
Proteases (Falciparum and chlamydia)
Pore-forming proteins (PFP's)
Unique methods (Toxoplasma gondii)
Term
Erythrocyte schizogony proceeds from
Definition
Young troph-Applique forms, motile, contribute to early stippling
Immature schizont- 2 or more nuclei, more stippling and expanded cytoplasm
Mature schizont- Max stippling and a lot of endomitotic reduction division
Merozoites released
Term
Merozoites that enter RBC to begin the process of gametogenesis create
Definition
Microgametocytes (Male)
Macrogametocytes (Female)
Which can be picked up by the mosquito in another blood meal
Term
What happens when ingested gametocytes begin sporogeny in a new mosquito?
Definition
Sporogeny begins in mosquito GIT, microgametocyte emerges from its ingest RBC s a motile sperm and fertilizes macrogametocyte. Zygote (Product of sperm and egg) form a sporozoite
Term
Ookinete
Definition
Develops from fertilized plasmodium ova. Matures via EMRD to sporozoites. Invades mosquito GIT epithelial cells
Term
Where must the sporozoite mature in the mosquito to enter the infective stage?
Definition
In the salivary glands
Term
Merozoite
Definition
Non-motile and invades RBC's
Term
Sporozoite
Definition
Motile
Invades liver cells
Term
What can result due to cellular material buildup caused by malaria?
Definition
Nephrotic syndrome
Term
Plasmodium vivax
Definition
Found in almost all endemic areas. Infected RBC's appear to be larger than non-infected RBC's. May have Schuffner's Dot
10-17 day inc period
Term
Young plas vivax troph
Definition
Applique form
Term
PLas vivax symptoms include
Definition
Headache, photophobia, Musular aches, nausea, vomitting.
Term
Plasm vivax Primary attack stage
Definition
Primary attack followed by periodic paroxysms and sudden chills, hot stage, severe frontal headaches, backaches. Patient becomes excited flushed and disoriented
Term
Plasm vivax sweating stage
Definition
Profuse sweating, exhausted (sleeps 10-12 hours), feels fine upon awakening
Term
The effects of plasm vivax due to hemolysis and liberation of RBC metabolites. In vivax malaria only what cell is affected and what does this cause?
Definition
Retics
Causes increased phagocytosis, hemolysis, spleen size and liver size
Malarial pigment may collect in the spleen
Term
For what type of malaria would it not be unusual to get thrombosis in the capillaries of the brain and why?
Definition
Falciparum
Because of the antigen antibody complex
Term
Malaria serum chemistry results
Definition
Decreased albumin and globulin
Increased potassium due to hemolysis
Term
Plas falciparum fever pattern
Definition
Merezoites released= High fever
Schizogony = Temp fluctuates and then decreases
Merozoites released again = High temp
Term
Anemia due to malaria would cause
Definition
Microcytosis, hypochromia due to hemolysis by parasite, interference with hematopoiesis and capillary hemorrhage
Term
Blackwater Fever
Definition
Occurs during falciparum infection
Intravascular hemolysis, hemoglobinemia and hemoglobinuremia.
Hemoglobin cysts and tubular epithelial cells in the urine (Pee is black)
Term
Hemoflagelates are
Definition
Likely pathogens in certain situations
Term
Anoher name for Leishmanial stage
Definition
Amastigote
Term
Anoher name for Leptomonad stage
Definition
Promastigote
Term
Another name for Crithidial stage
Definition
Epimastigote
Term
Anoher name for Trypanosomal stage
Definition
Trypanomastigote
Term
Hemoflagelates replicate by
Definition
3-step process that involves longitudinal fission
Term
Trypanosoma brucei
Definition
Causes African trypanosomiasis
Term
Trypanosoma brucei Life cycle for
Definition
1.Take blood meal which contains trypanosomal stage.
2. Morphs into crithidial stage
3. Another fly takes blood meal with the organisms in the crithidial stage
4. Those organisms then molt into the trypanosomal stage
Term
Why does molting in the Tse tse fly occur?
Definition
Due to metabolic differences in teh GIT of the Tsetse fly vs the human CVS
Term
Vector for trypanosoma brucei
Definition
Glossina palpalis (W)
Glossina mordisans (E)
"Tsetse Fly"
Term
Trypanosoma brucei inc period
Definition
5-30 days
Trypanosomal stages in the patient's CVS
Blood smear pos
Parasitemia fluctuates
Trypanosomes invade the lymphatics and colonize the lymph nodes
Enlargement of the cervical LNS (Winterbottom's sign)
Increased lymph count
Increased IgM
Term
Syndrome phase of Trypanosoma brucei
Definition
Trypanosomes invades the CNS
Apathy
Fatigability
Somnolence sleepy
Emaciation
Character changes
Paraplegia
Coma
Death
Term
What kind of specimen is appropriate late in the process for both Trypanoma species
Definition
CSF
Term
Example of how human error can increase parasites
Definition
Europeans teach Africans to burn grass at then end of growing season to return nitrogen to the soil quicker. Burning of the grass reduced ant population which is the predator of the Glossima pupae. Without ants the Glossima pupae increased. Europeans shot leopards who were the primary predators of antelope whose population increased. The increase in Antelope caused an increase in Glossima who were their primary food source.
Term
Nematode
Definition
"Roundworms" Contain a plasmid (Olfactory organ), most are freelviing, important parasites of plants and about 80,000 are parasites to vertebrates.Found in warm region of the world. Females usually twice the size of males.
Term
General characteristics of Nematodes
Definition
Oral opening
Anterior digestive tract
Muscular esophagus
Usually pale in color unless gravid female
Non-cellular (secreted) hard cuticle covering
Term
Uniform lumen
Definition
Filiform larva
Term
Lumen expanding to posterior bulb
Definition
Rhabditiform larva
Term
Male nematode characteristics
Definition
Males have a copulatory spicule
Term
Ascaris lumbercoides
Definition
10-20cm. Found in Temperate and tropical regions
Term
What conditions may cause a 50% penetration rate?
Definition
Indiscriminated defecation
Warmth (20-25 degrees Celsius)
Soil is clay or heavy loam
High humidity
Areas of poor sanitation often have 100% penetration
Term
A single infected ascaris lumbercoides host may have how many parasites a day?
Definition
3-4 up to 1,000 parasites.
May produce 2-3 x 10^7 eggs/day/patient
Avg 2 x 10^5 eggs/day/female for 6 months-1 year
Term
Ascaris lumbercoides life cycle (Takes 2 1/2 months in hist. 2.5 weeks in the external environment)
Definition
1. Person eats embryonated ovum
2. Larvae escapes covering and travels to small intestine, liver, cardiovascular system, lung, cardiovascular system
3. Then travels to pharynx where they stimulate nerve endings, are swallowed and enter the GI tract
4. Pooped out eventually
Term
Acaris eggs in feces require what?
Definition
Warm moist soil and a 5-8 degree decrease Celsius
Term
Male Ascaris lumbercoides have
Definition
Dorso flexion (Curved tail)
Term
Ascaris infections in children may cause
Definition
Stunted growth
Term
Adult Ascaris worm infection may cause
Definition
High worm burdens, Abdominal pain and intestinal obstruction
Term
Ascaris infections
Definition
Early on the patient is asymptomatic and may see Colic C in children, lactose indigestion in some
Lung phase of larval migration
Pulmonary symptoms include cough, dyspnea, hemoptysis (Hemorrage from 20mm diamter larvae in 10mm diameter alveolar capillaries) eosinosis pneumonitis, Loeffler's syndrome (also with increased IgG and IgM)
Term
Migrating adult Ascaris worms may cause
Definition
Symptomatic occlusion of the billiary tract, oral expulsion and rectal expulsion
Term
What is the tpyical microscopic procedure for identification of ascaris eggs in the stool?
Definition
1. Collect stool specimen
2. Fix specimen in 10% formalin
3. Concentrate using the formalin-ethyl acetate sedimentation technique (Rictchre)
4. Examine a wet mount of the sediment
Term
What quantitative assessments can be used to identify ascaris eggs?
Definition
Kato-kanz procedure
Larvae can be identified in sputum or gastric aspirate during pulmonary migration phase. Formalin fixed organisms for morphology. Adult worms passed in stooll
Term
Enterobius vermicularis
Definition
Most common helminth in temperate regions, aided by close, crowded indoor living. 2.5mm x 0.2 mm (Male) 8-13mm (Female) Habitat is the end of the small intestine/cecum/ beginning of the colon
Term
Describe the egg laying process of enterobius vermicularis
Definition
Female migrates down the colon to the rectum and crosses through the anal sphincter late at night. In the mornin she deposits 10,000-15,000 eggs and then dies
Term
Enterobius vermicularis eggs can survive for how long. How long does it take for full embryonation?
Definition
Eggs survive 2-4 weeks.
Embryonation takes 3-5 hours
Term
Enterobius vermicularis life cycle
Definition
1. Person eats ovum
2. Larvae attach to end of small intestine and mature
3. Adult females migrate to periannal region late at night to lay eggs
Term
Enterobius vermicularis patho
Definition
Patient is asymptomatic, puritic (itchy), poor sleep, irritability
Term
Lab dizgnosis fo enterobius vermicularis includes
Definition
Scotch tape test
Term
Hookworms
Definition
Ancyclostoma duodenale (Old worm hookworm)
Necator Americanus (New world hookworm. came to America upon arrival of African slaves)
Term
Hookworm life cycle
Definition
1.Filariform larva (infective stage) penetrate skin by crawling up foot and cause allergic reation.
2. It ends up in the circulation where it may enter the CVS because of increased oxygen tension.
3. From the CVS it travels to lungs, trachea and pharnyx where it is swallowed.
4. Matures in small intestine
5. Eggs release in feces and mature in the soil to rhabditiform larvae, then they develop into filariform larvae
Term
When hookworms attach to the small intestine and suck blood. They may cause what?
Definition
Microcytic, normochromic anemia
Term
Hooworm rhabdidiform to filaria takes how long
Definition
2-5 days (2 molts)
Term
Hooworm rhabdidiform compared to filariform
Definition
Rhabdidiform is shorter and more muscular while the filariform is longer and skinnier
Term
Hookworm egg volume
Definition
L x W^2 (Allows for discrimination beetween hookworm eggs and Ter. derminutis eggs)
>170,000 u^3 = Ter. derminutis
<150,000 u^3 = Hookworm
Term
Some hookworm diagnosis methods
Definition
Find ova in stool
Semi-quantitative
-Stoll count
Hookworm culture
-Baerman appartus
Term
Strongyloides stercoralis
Definition
Same as the hookworm but the Female larva is fertilized by the male larva in the lungs
Term
What is the only nematode that can survive its entire life cycle outside of the body?
Definition
Stronglyloides stercoralis
Term
Strongyloides stercoralis patho
Definition
Asymptomatic, rash, symptoms of pneumonia, chrome diarrhea (up to 30 years)
Steatorrhoea, dehydration, low-grade fever
Term
Trichuris trichuria
Definition
Known as the "Whip worm" or "Hair tail"Present worldwide but most common in tropical areas
Term
Trichuris trichuria life cycle
Definition
1. Ingest fully embryonated egg
2. Hatches and feeds in vila
3. Matures to adult in the ceum
Term
Trichuris trichuria patho
Definition
Asymptomatic
Prolapse of the rectum
Anemia
Mild eosinophilia
Term
Trichinella spiralis
Definition
Causes trichinosis. Known as the "trichina worm". Can be found encysted in the meat of pork, bear, walrus and others.
Term
Trichinella spiralis patho
Definition
Adults may get cramps, diarrhea, muscle twitching/weakness
Larva entering the CVS may cause eosinophilia, and peri-orbilal edema.
Term
Filariodea
Definition
Differ from most other neamtodes by using an arthropod vector. Adults live in the tissue of a vertebrate host
Female does not lay eggs but rather is viviparous in delivery
Term
Microfilaria development
Definition
Microfilaria develop in human CVS, then futher develop into the filariform in the vector.
Term
Microfilaria
Definition
Ribbon-like not nucleated to the very end of the organism
Term
Filariform male dies when what occurs?
Definition
After fertilization of the female
Term
Two groups of Filariodea
Definition
Filarids (found in the tropics) and Tissue worms (found in the Western Hemisphere)
Term
Filarids include
Definition
Brugia malayi
Wuchereria bruncofti
Mansonella ozzardi
Dipetalonema perstans
Loa loa
Term
Upper extremity elephantitis can be caused by which organisms
Definition
Brugia malayi
Wucheria bancrfoti
Term
Tissue worms include
Definition
Onchocerca volvulus
Dipetalonema streptocerca
Term
Wuchereria bancrofti (Lower extremity problems) vectors include
Definition
Ades spp
Culex spp
Anophales spp
Mansonia spp
Term
How many microfilaria must the vector pick up to continue an infection in another organism?
Definition
More than 10
If he picks up more than 100 he dies
Term
Wuchereria bancrofti symptoms
Definition
Tenderness
Swelling
Fever
Known as Munu
Term
Brugia malayi
Definition
Upper extremitites
Term
Mansonella perstans
Definition
Adults found in peritoneal cavity or lungs
Term
Mansonella ozzardi
Definition
Vector Biting Midge "Blackfly"
Term
Trematodes Class distinction
Definition
Class Turbellaria
-most are free-living, no human parasites
Class Trematoda
-All are parasitic "flukes"
Term
Trematoda can be monogenea which means
Definition
They have 1 host and are ectoparasites of fish
Term
Trematoda can be digenea which means
Definition
They have 2 or more hosts and are ectoparasites of reptiles and birds
Term
Trematoda characterstics
Definition
Dorsoventrally flat, do not have coelom, have an incomplete digestive tract and most are hemaphroditic and self fertilizing
Term
Life cycle of Trematoda
Definition
Term
Schistoma spp
Definition
Only medically significant trematode to not be hermaphroditic, thrive in ditches, cause problems at places such as the great dam at Aswan, Egypt
Term
Schistosoma mansoni
Definition
Vectored planorbiadae (Snail family)
Term
Schistosoma life cycle
Definition
Term
Clonorchis sinensis
Definition
Metacercaria form is encysted in fish muscle tissue. Clonorchis sinensis is endemic in Kore, China. Live in bilary ducts and the presence of adults can cause inflammationa and intermittent obstruction
Term
Clonorchis sinensis patho acute phase
Definition
Ab pain, nausea, diarrhea
Term
Clonorchis sinensis patho chronic infection
Definition
Cholangitis
Cholelithiasis
Pancreatitis
Term
Opsithurcis/ clonorchis ultrasound will show
Definition
Multiple liver absesses and cystic or "mulberrry-like" dilations
Term
Metagonimiasis
Definition
Far East, Siberia
Term
Metagonimiasis patho
Definition
Diarrhea
Colicky ab pain
Migration of the eggs to extraintestinal sites such as the heart and brain
Term
Heterophyes heterophyes
Definition
Egypt, Middle East. Cause diarrhea and colicky ab pain
Term
Heterophyes heterophyes life cycle
Definition
Term
Cestoda
Definition
"Tapeworms".Consist of a scolex (head) and a strobula (proglottid). All are hermaphroditic. Capable of self fertilization from one proglottid to the next
Term
Cestoda life cycle
Definition
1. Person ingests organism which was encysted in the muscle tissue of fish.
2. Scolex attaches to small intestine and sucks in nutrients
3. Proglottids begin to form
4. Eggs formed in feces
5. Eggs embyryonate in the water
6. Coracidia hatch from eggs and are ingested by copapods
6. Larvae forms inside copapods
7. Fish eat copapod and plerocercoids form in the fish muscle.
Term
Cysticercus larva
Definition
Found in cow and pigs
Term
Procercoid larva
Definition
Found in cepepod
Term
Piercercoid larva
Definition
Fish
Term
Cysticercoid larva
Definition
Insect
Term
Acetabulum type
Definition
Vinegar cup
-Rostellum with or without hooklets
Term
Bothria type
Definition
Multiple bothria
Term
Raised, armed rostellum
Definition
Taenia pisiformis
Term
Cestode Female reproductive organs include
Definition
Ovary
Oocyte
Uterus
Uterie pore
Vagina
Term
Cestode Male reproductive organs include
Definition
Testes
Term
Dibothriocephalus latus
Definition
Fish tapeworms, broad tapeworms. Distinguishing features include the uteran pore and multiple genital pores. 2 "lip" type flaps with two sucers at the end of the scolex
Term
Dibothriocephalus latus life cycle
Definition
1. Human ingests pleurocercoid which was encysted in muscle tissue of fish
2. Scolex attaches to intestine and matures to an adult
3. Unembryonated eggs passed in the feces
4. Once in water, eggs are embryonated and referred to as Hexacanth embryo or onchosphere
5. Matures into caracidium and is ingested by a copapod which is then eaten by a fish
Term
Dibothriocephalus latus patho
Definition
Asymptomatic, B12 deficiency (if the scolex attaches to the proximal jejunum selectively absorbs B12
Patient will have pernicious anemia and spargenosis
Term
Non-human (usually) species invades
Definition
All human tissues and are "ectopic" and migrate to tissue into a sporganum. Often caused by applying tissue (frog, snake) to open wound
Term
Lab diagnosis for Dibothriocephalus latus
Definition
Look for opercular knob
Term
Cyclophyllideas
Definition
Taenia solium
Taenia saginata
Term
Taenia solium
Definition
Common in the U.S. comes from undercooked pork.
1. Intermediate host, 1 adult/Primary host. 4-7 metes. 1 per person. Rasied, armed rostellum
Term
Taenia saginata
Definition
"Beef tapeworm". Frequent in the U.S. 8-15 meters. Usually no more than 3 per patient. Stump rostellum. 6.0 x 10^8 ova/yr/scolex
Term
Taenia lifecycle
Definition
1. Humans ingest scolex in pig/cow muscle tissue
2. Scolex attache to small intestine and matures to adults
3. Eggs or gravid proglottids are passed in feces into the environment.
4. Cows and pigs eat infected grass
Term
Proglottids from taenia species can do what once they are in the GIT?
Definition
Crawl out of the GIT, creep along the ground and disintegrate, spreading their eggs.
Term
Taenia solium patho
Definition
Asymptomatic
Vague ab pain
Hunger/drowsiness
Chronic indigestation
Term
Taenia saginata patho
Definition
Asymptomatic. Cysticercosis. Often called custocarcis boving.
Term
Lad diagnosis of Taenia spp
Definition
Find ova or proglottid in feces. Examine proglottid and use 10%EtOH slowkill to prevent the uterus from contracting
Term
Echinococcus granulosus
Definition
Causes hydatid cyst disease
Dog tapeworm
Larval stage (cyst) infects humans. Occurs in cattle, sheep and goat raising countries
Term
Echinococcus granulosus life cycle
Definition
1. Eggs passed in dog feces
2. Ingested in humans and travel to small intestine
3. Lodge in the lungs
Term
Hymenolepis diminuta
Definition
Rat parasite with a peach pit ova
Term
Hymenolepis nana
Definition
Rat parasite, patients are often asymptomtic
Term
Dipylidium caninum
Definition
Dog parasite
Term
General intestinal amoeba life cycle
Definition
1. Person eats infective cyst in contaminated food or water.
2. Cyst excysts in colon and reproduces asexually.
3. Infective cyst exits in formed stool, troph passes in liquid or soft stool and intestinal wall erosion (by ent. histolytica which leads to liver via the circulatory system and then to a hepatic abscess.
Term
Leishmania spp life cycle
Definition
1. Sandfly bites human and regurgitates promastogote into the person.
2.Promastigota transforms into an amastigote and multiplies intracellularly. 3. Amastigote is then ingested by sand fly and transformaed into promastigote in the midgut of the fly.
Term
Which organism has a safety pin fibril
Definition
Chilomastix mesnili
Term
Patient diagnosis process
Definition
1. Patient presents with signs, symptoms and appearance.
2. History and physical
3. Physician created Rule out List (Differential diagnosis)
4. Objective information. Orders lab tests, etc
5. Diagnosis
6. Therapy
7. Assessment of post treatment progress
Term
Paragonumus westermani Life cycle
Definition
1 Person consumes metacercariae from inadequately cooked crustaceans
2. Excysts in duodenum
3. Entitiy develops into and adult fluke in the lungs
4. Expel organism in sputum or feces
5. Travels to water and embryonates. Hatches and penetrates.
Can be obtained by eating raw crabs or fish
Term
Paragonimus kellicotti
Definition
Endemic to North America
Causes pain and severe coughing, hemoptysis
Term
Fasciola (Found wherever sheep and cattle are raised) Life cycle
Definition
1. Eggs released in stool and become embryonated in the water.
2. Eggs release miracidia which invade a snail host
3. Parasite matures (sporocyst, rediae, cercariae
4. Cercariae escape from snail and encyst as metacercariae on aquatic vegetation.
5. Humans ingest the plants and the metacercariae excysts in the duodenum
6. Travel to the biliary ducts where they mature into an adult fluke
Term
Localized dermatitis caused by what parasite
Definition
Schistosoma cercarial penetration
Term
Parasite first found in Egyptain mummies
Definition
Schistosoma
Term
Cercarial dermatitis
Definition
Caused by metacercariae of schistosoma at skin penetration, causes petechial hemorrhage
Term
Acute schistosomiasis
Definition
Caused by schistosoma, causes katayama fever, looks like serum sickness, could cause hepatosplenomegaly, lymphadenopathy and eosinophilia
Term
Schistosoma haematobium
Definition
Can cause pulmonary issues
Term
Schistosoma can cause
Definition
Bacterial complications with mostly salmonella spp
Circulating immune complexes.
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