Term
If a person has an H gene then which antigen is on their red blood cells? |
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Definition
fucsyl transferases which adds L-fuctose to the base of the immunodominant structure of H antigen |
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Term
If a person has an A gene then which antigen is on their red blood cells? |
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Definition
galactosaminyl-transferase that adds N-acetyl-galactosamine to the H (L-fructose) base |
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Term
If a person has an B gene then which antigen is on their red blood cells? |
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Definition
galactosyl-transferase adds D-galactose to the H (L-fructose) base |
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Definition
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Definition
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Definition
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Definition
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Term
Characteristics of the ABO antibodies |
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Definition
naturally occurring, anti-b (A blood), anti-a (B blood), both (O blood) or neither (AB blood), Attack foreign antigens on the RBC surfaces |
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Term
Distinction and practical importance between A1 and weaker subgroups of A. |
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Definition
A1 gene allows for more A antigens to be expressed on the RBC surface, A2 genes do not code for as many enzymes so not as many antigens are A |
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Definition
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Definition
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Steps to be taken when forward and reverse do not match? |
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Definition
order a new specimen, wash the specimen (retest), look at patient file, determine the cause of the discrepancy |
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Term
Who discovered the ABO blood group system and when did he discover it? |
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Definition
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Term
What is Landsteiner's Rule? |
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Definition
reciprocal antibodies are consistently and predictably present in the sera of normal people whose rbcs lack the corresponding antigen
If you have the antibody you CANNOT have the antigen |
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Term
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Definition
A antigens, Anti-B antibody |
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Term
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Definition
B antigens, Anti-A antibody |
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Term
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Definition
A and B antigens, no antibodies |
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Term
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Definition
neither antigen, anti-a and anti-b antibodies |
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Term
What does ABO inheritance follow? |
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Definition
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Term
What is the most frequent blood type? |
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Definition
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Term
Why do babies give weaker ABO results? |
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Definition
because antigens are not fully developed |
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Term
Where are ABO antigens located? |
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Definition
RBCs, lymphs, platelets, tissue cells, bone marrow and solid organs |
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Term
Are antigens direct products of genes? |
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Definition
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Term
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Definition
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Term
Immunodominant structure of H antigen |
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Definition
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Term
Immunodominant structure of A antigen |
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Definition
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Term
Immunodominant structure of B antigen |
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Definition
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Term
An emergency transfusion of packed RBC's is required for a premature newborn. What ABO type should be issued for transfusion? |
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Definition
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Term
Which of the following is true of ABO antibodies? |
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Definition
They are "naturally occuring" antibodies |
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Term
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Definition
OO offspring with O phenotype not possible |
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Term
Individuals of blood group O have: |
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Definition
The isoagglutinins A and B in their plasma |
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Term
Which phenotype is seen more frequently in the "white" population than the "black" population |
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Definition
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Term
Given a mother of Group O and an infant of Group B, which of the following blood groups of the questionable father would eliminate his paternity? |
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Definition
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Term
Which of the following ABO blood groups contains the least amount of H substance?\ |
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Definition
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