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Exam 1
Obligate Intracellular Bacteria
41
Microbiology
Graduate
02/15/2013

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Cards

Term
How are Chlamydia trachomatis serotypes D-K diseases transmitted?
Definition
sexual contact hand to eye, or congenitally
Term
What does Chlamydia trachomatis serotypes D-K cause?
Definition
urethritis, cervicitis, PID, epididymitis, infant pneumonia, and conjunctivitis.
Term
How are Chlamydia trachomatis serotypes A, B, Ba and C transmitted?
Definition
hand to eye or by flies
Term
What does Chlamydia trachomatis serotypes A, B, Ba and C cause?
Definition
multiple persistent ocular infections which can lead to blindness
Term
How are Chlamydia trachomatis serotypes L1, L2 and L3 transmitted?
Definition
sexual contact
Term
what does Chlamydia trachomatis serotypes L1, L2 and L3 cause?
Definition
primary genital lesions and secondary acute lymphadenitis.
Term
List the 3 types of diagnositc tools used to detect chlamydial infections
Definition
cytology, culture and antigen dectection
Term
epidemiology of psittacosis
Definition
Psittacosis is a disease caused by Chlamydophila psittaci. This bacterium is endemic of birds but humans can acquire the bacteria by inhalation of aerosols of bird feces. The presentation can include pneumonia, or be asymptomatic.
Term
clinical significance of Clyamydophila pneumoniae
Definition
it can cause community acquired pneumonia with a non-productive cough. It can also cause bronchitis, pharyngitis, flu-like diseases, and coronary artery disease (found in plaque).
Term
Rocky mountain spotted fever
Definition
caused by R. rickettsii in ticks, seen in North/South America and SE united states
Term
Rickettsialpox
Definition
caused by R. akari in mites, seen worldwide
Term
Mediterranean spotted fever caused
Definition
R. conorii in ticks, seen in southern Europe, the middle east, Africa and India (Indian tick fever)
Term
Epidemic typhus
Definition
R. prowazekii in lice, seen worldwide
Term
Murine (mouse) typhus
Definition
caused by R. typhi in fleas, seen worldwide
Term
Scrub typhus
Definition
caused by orientia tsutsugamushi in chiggers, seen in southern and southeastern Asia, and the south pacific
Term
Human monocytic ehrlichiosis
Definition
caused by E. chaffeenis in ticks, seen in southeastern and south-central united states
Term
Human granulocytic ehrlichiosis
Definition
caused by E. ewingii in ticks, seen in the US
Term
Human granulocytic anaplasmosis
Definition
caused by Anaplasma phagocytophilum, seen in the US and Europe
Term
Nucleic acid probes and amplified probes
Definition
molecule techniques with PCR, they do not hold up in legal courts to prove child abuse. f
Term
EIA
Definition
less expensive and allows for screening of large amounts of specimens, but it is not very sensitive
Term
Immunofluorescence
Definition
fluorescent stain which allows for quantitative analysis but it is labor intensive and cannot be performed on urine specimens
Term
How is Chlamydia diagnosed (3)
Definition
cytology (low sensitivity), culture (labor intensive and expansive), or antigen detection methods
Term
How is Chlamydophila pneumoniae transmitted and what does it cause
Definition
via coughing; it caused community acquired pneumonia, bronchitis, pharyngitis, flu-like disease and coronary artery disease.
Term
How is Chlamydophila psittaci transmitted and what does it cause
Definition
transmitted via inhalation of bird poop, it causes pneumonia.
Term
What does chlamydia trachomatis L1, L2, and L3 cause
Definition
lymphogranuloma venereum
Term
What does chlamydia trachomatis A, B, Be and C cause
Definition
trachoma
Term
how is chlamydia trachomatis L1, L2 and L3 transmitted
Definition
sexually
Term
2 ways that chlamydia trachomatis A, B, Be and C is transmitted
Definition
hand to eye, flies
Term
3 ways that chlamydia trachomatis D-K is transmitted
Definition
sexually, hand to eye, and congenitally
Term
Describe the Rickettsia replication cycle
Definition
obligate intracellular parasite which multiples by binary fission and is transmitted by arthropods.
Term
Describe the Chlamydia replication cycle
Definition
unique replication cycle in which there is an elementary body which is round, and an inclusion body which is round and vacuolar
Term
How is Chlamydophila diagnosed?
Definition
serology (serum specimens need to run in tandem to see the antibody titer), culture and PCR.
Term
What is the causative agent of Louse-borne typhus?
Definition
R. prowazekii
Term
What is the mode of transmission of Louse-borne typhus?
Definition
mode of transmission to humans is seen in severe overcrowding conditions (trench fever WWI and concentration camps WWII), it is transmitted via lice.
Term
What is the causative agent of Rocky Mountain Spotted Fever?
Definition
R. rickettsii
Term
What is the mode of transmission of Rocky Mountain Spotted Fever?
Definition
mode of transmission to humans is via ticks. Only 30-40% of people infected get spots and it is not endemic in the northern tick population.
Term
What is the causative agent of Scrub typhus?
Definition
Orientia tsutsugamushi
Term
What is the mode of transmission of Scrub typhus?
Definition
chiggers
Term
Coxiella burnetti
Definition
endemic to cows, sheep and goats, causes Q fever, GN
Term
Tropheryma whipplei
Definition
whipples disease in white, middle aged men, seen in macrophages, GP
Term
Calymmatobacterium granulomatis
Definition
donovans disease in india, seen in monocytes, GN
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