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exam 1
exam 1 micro
119
Microbiology
Undergraduate 4
04/05/2011

Additional Microbiology Flashcards

 


 

Cards

Term
organism
Definition

any living thing

 

Term
pathogen
Definition
disease causing organism
Term
pathogenicity
Definition
ability of pathogen to gain entry to host tissue and bring about disease
Term
virulence
Definition

"full of poison"

 

DEGREE to which a pathogen causes disease

Term
Prokaryotic
Definition
a cells whose genetic material is not enclosed in a nuclear membrane
Term
Eukaryotic
Definition

a cell having DNA inside a distinct membrane-enclosed nucleus

 

Term
Binomial Nomenclature species
Definition

the system of having two names

 

(Clostridium tetani)

Term
Genus
Definition

a group of closely related species

 

Term
sp
Definition

refers to a species in singular-

 

uknown species of a known genus

 

Term

spp

 

Definition

refers to a species in plural

 

refers to all members of a genus

Term
Strain
Definition

indentified by numbers, letters or names that follow species

 

Term
Clone
Definition
group of organisms all derived from a single parent cell
Term
Cocci
Definition

Single Cell

 

(circle form)

Term
Bacilli
Definition
Rod shaped
Term
Spirilla
Definition
sprial shape
Term
Bacterial capsule
Definition
the glycocalyx is organized and formly attached tothe cell wall forming thick layer outside of the cell
Term
Flagella
Definition
Long whip like structure for motility
Term
Axial filaments
Definition
spirochetes move by means of axial filaments
Term
fimbriae
Definition
short, straight projections for attachment involved in biofilm formation that allow attachment to a host
Term
sex Pilus
Definition

longer, one--two per cell for transfer of the DNA in mating process

 

Term
Endospore
Definition
a survival form of bacteria produced within the cell in response to adverse environmental conditions
Term
Pathology
Definition
Term
Etiology
Definition
Study of cause of disease
Term
Infection
Definition
state were host harbors microbes that survive and multiply in body tissue
Term
Disease
Definition
process or even that results in any change from the general state of health
Term
Opportunistic pathogens
Definition
Term
Acute disease
Definition
develops rapidly and last a short period of time
Term
Chronic disease
Definition
develops slowly, lasting a long time
Term
Communicable disease
Definition
Term
noncommunicable disease
Definition
Term
primary infection
Definition
1st pathogen to infect a body part
Term
secondary infection
Definition
infection of a body part by a 2nd pathogen
Term
Compromised host
Definition
Term
Zoonoses
Definition
a disease of animals that can be transmitted to humans
Term
Fomite
Definition
Term

Vectors

 

(mechanical and biological)

Definition
Term
Epidemiology
Definition
the study when and where diseases occur and how they are transmitted and occurence
Term
Adhesins
Definition
Term
Phagocytosis
Definition
Term
Collagenase
Definition
dissolves collagen; softens tissue so it can spread
Term
Leukocidin
Definition
kills white blood cells; decreases hosts resistance
Term
Hemolysin
Definition

causes hemolysis

(lysis of red blood cell)

Term

Hemolysis:

 

alpha

beta

gama

Definition

alpha--partial : greenish zone around colony

 

Beta--complete hemolysis--clear, odorless zone around colony

 

Gama- No hemolysis

Term
5 baisc groups of Microbes
Definition
  • Fungi
  • Protozoa
  • Virsuses
  • bacteria
  • algae
Term
beneficial effects of microbes
Definition
  1. oxygen (from the ocean 50%)
  2. food
  3. soil microbes break down waste
  4. microbes in intestines for digestion
Term
Anton van Leeuwenhoek
Definition
  • 1st person to observe microbes through magnifying glass
Term
Ernst Ruska
Definition
made first Electron microscope
Term
Ignaz Semmelweiss
Definition
hospitals needed to wash hands
Term
Louis Pasteur
Definition
Germ theory of disease
Term
Robert Koch
Definition
first to  cultivate anthrax
Term
Microbial Taxonomy
Definition
classification of microorganisms
Term
Virulence degrees (3)
Definition
  1. Highly virulent
  2. moderatly virulent
  3. avirulent
Term
Prokaryotic and Eukaryotic similarities
Definition
  • both have membranes
  • both use DNA to encode genetic material
Term
What do prokaryotic cells lack?
Definition
internal membrane-enclosed organelles
Term
Characteristics of Prokaryotes
Definition
  • unicellular
  • contains one circular chromosome
  • no nucleolus
  • lacks membrane-enclosed organelle

 

Term
Cell wall of Prokaryotes
Definition
  • Contains polyssacharide peptidoglycan
  • has flagella
  • No cilia
Term
Cell wall of Eukaryotes
Definition
  • cell wall is chemically simple
  • may have cilia or flagella
Term
Binary fission
Definition
[image]
Term
mitochondria and chloroplast have how many ribosomes?
Definition
70s
Term
what does the THREE DOMAINS consist of?
Definition
  • two prokaryotes
  • one eukaryotes
Term
What are the THREE DOMAINS?
Definition
  1. Archaea
  2. Bacteria
  3. Eukarya
Term
Classifications of THREE DOMAINS?
Definition
  1. Archaea--live in extreme habitates, bacteria-like
  2. Bacteria--cell wall have peptidoglycan
  3. eukarya--all ekaryotic organisms
Term
Bacteria are:
Definition
  • Prokaryotic
  • have cell wall
Term
Shape of coccus?
Definition

Spherical

 

pairs=diplococci

Term
name of cocci in 4s?
Definition
tetrads
Term
name of cocci in 8s?
Definition
sarcinae
Term
Streptococci shape
Definition
chaines
Term
shapes of staphylococci
Definition
grape-like
Term
Vibrios
Definition
curved like rods
Term
prirochetes
Definition
long spirilla with many tight coils
Term
Glycocalyx
Definition
substance that surrounds cell
Term
what is the glycocalyx made of?
Definition
Slimey layer
Term
Function of Bacterial Capsule
Definition
  • enables bacteria to resist phagocytosis by host defense cells
  • allows some bacteria to adhere to surfaces and colonize and resist flushing
  • prevents cell from dehydration and chemicals and loss of nutrients
Term
Biofilm
Definition
a microbial community that forms a slimy layer on a surface
Term
CDC says biofilms are involved in what percentage of all human bacterial infection?
Definition
70%
Term
Function of biofilm
Definition
  • Resist disinfectants
  • resist anti-biotics
Term
Bacteria that lack flagella are called?
Definition
atrichous
Term
4 types of arrangements of flagella
Definition
  1. monotrichous- single
  2. amphitrichous-single and both ends
  3. lophotrichous-two or more at one or both ends
  4. peritrichous- all over cell

 

Term
Gram positive characteristics
Definition
  • layers of peptidoglycan
  • teichoic acids= alcohol and phosphate (function as antigen)
Term

why is it important to know gram + from gram - ?

 

Definition
to choose the best control method
Term
characteristics of Negative cell wall
Definition
  • one or few peptidoglycan and outer membrane of protein and fat
  • no teichoic acid
  • lipplyssacharide in outter membrane
  • lipoproteins and phospholipids too
Term
primary stain color?
Definition
crystal violet
Term
mordant define
Definition
agent that fixes the stain to cell
Term
if iodine present in gram staining?
Definition
cells become darker violet
Term
countersaint name and color?
Definition
  • Safranin
  • turn reddish-pink or remain purple
Term
Lipid bilayer
Definition
the phospholipids that are arranged in two parallel rows
Term
cytoplasm
Definition
cell liquid
Term
2 subunits of ribosomes
Definition
  1. protein
  2. ribosomal RNA
Term
Plasmid
Definition
  • bacteria that contain circular, double-stranded DNA
  • small loops of extrachromosomal DNA
Term
Function of plasmid
Definition
  1. carry genes for virulence or drug resistence
Term
Sporulation
Definition
process of endospore formation within a vegitative cell
Term
germination
Definition
endospore returns to its vegitative state
Term
how to kill spores
Definition
  • steam autoclave
  • gas autoclave
  • some disinfectants
  • powerful radiation
Term
Symbiosis
Definition
relationship between normal flora and host
Term
Opportunistic microbes
Definition
  1. require a special opportunity to produce disease such as injury or impaired host defenses
  2. same organism can often produce a variety of problems
  3. common organisms, frequently encounteredor already carried
  4. cause secondary infection
Term
True pathogens
Definition
  1. able to infect healthy host under own power and initiate disease
  2. produces one specific disease
  3. not so common
  4. cause of primary infection
Term

What did Koch Postulate?

 

Definition
  1. organism must be present in every case of disease
  2. organism must be isolated in pur culture from a diseased host
  3. pure culture must produce the disease when inoculated into a healthy, susceptible host
  4. organism much be re-isolated in pure culture from infected experimented host
Term
Function of Kochs postulation
Definition
  • to prove that certain microbes cause certain diseases
Term
endemic
Definition
  • constantly present in a population
Term
subacute disease
Definition
disease that is intermediate between acute and chronic
Term
Focal Infection
Definition
  • local infection enters a blood vessel and spreads to other parts of body
Term
Bacteremia
Definition
bacteria in blood
Term
Sepsis
Definition
  • toxic inflammatory condition arising from the spread of microbes and toxins
Term
what does sepsis cause?
Definition
  • edema
  • dyspnea (breathing diff)
  • fever
  • confusion
Term
once in body, what are the sequence that disease follows?
Definition
  1. incubation period
  2. prodromal period
  3. period of illness
  4. period of convalenscence
  5. contagious period
  6. levels of recovery

 

Term
Vectors
Definition
an organism that carries a pathogen such as animals carry pathogens from on host to another
Term
Noscomial infection
Definition
infection aquired in hospital
Term
Morbidity
Definition
incidence of a specific disease
Term
exotoxins
Definition
  • produced inside some bacteria then secreted outside
Term
Release of EXOTOXIN from LIVING bacterium
Definition
Term
Release of ENDOTOXIN from DEAD bacterium
Definition
Term
M protein
Definition
found on cell surface and fimbriae
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