Term
Mesenchymal cells DO NOT differentiate into |
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Definition
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Term
Where are Macrophage-like type A Synovial cells derived from |
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Definition
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Term
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Definition
clear, viscous liquid derived from blood plasma with high concentration of hyaluronan. Lubricant for joints. |
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Term
What do type A synovial cells do? |
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Definition
remove wear-and-tear debris from the synovial fluid and regulate inflammatory events |
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Term
What do type B (fibroblastic) synovial cells do? |
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Definition
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Term
What is involved in degradation of collagen? |
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Definition
Matrix metalloproteinases |
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Term
What are the three forms of cartilage? |
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Definition
Hyaline, Elastic, and Fibrocartilage |
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Term
What are the cells of cartilage? |
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Definition
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Term
What is the most common type of cartilage in the body? |
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Definition
Hyaline Cartilage (with type II collagen) |
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Term
Which ECM fiber has the defining structure of a triple helix? |
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Definition
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Term
What are the three types of collagens? |
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Definition
Fibrillar, Sheet-forming, and Linking/anchoring |
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Term
What type of collagen is the sheet forming collagen? |
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Definition
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Term
What type of collagen is fibrillar collagen? |
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Definition
I, II, and III (with type I being the most abundant) |
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Term
What gives the white adipose its natural color when freshly removed? |
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Definition
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Term
What gives brown adipose its natural color? |
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Definition
Cytochrome C and a large number of capillaries |
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Term
Norepinephrine released from nerve endings activates what hormone to break down what in adipocyte stimulation? |
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Definition
Hormone-sensitive lipase; breaks down triglycerides (converts to glycerol and fatty acids) Glycerol enters blood and is taken up by liver. Fatty acids bind to albumin to be transported throughout body. |
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Term
What is the most common type of cartilage in the body? |
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Definition
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Term
What is most abundant proteoglycan in the ECM? |
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Definition
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Term
What mediates adherence of chondrocytes to the ECM? |
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Definition
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Term
What is the primary type of collagen found in hyaline cartilage? |
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Definition
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Term
What is primary collagen found in fibrocartilage? |
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Definition
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Term
What distinguishes fibrocartilage from Elastic and Hyaline cartilage? |
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Definition
No distinct perichondrium |
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Term
Which compound is secreted by osteoblasts? |
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Definition
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Term
Osteocalcin is involved in what? |
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Definition
calcification of the matrix |
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Term
List and describe steps of endochondral ossification? |
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Definition
Cartilage forms a model of bone to be made, bone collar forms, degeneration of cartilage in bone collar, capillaries invade to provide osteoprogenitor cells, and osteoid is deposited by osteoblasts and is calcified |
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Term
Which type of bone is produced first? |
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Definition
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Term
What is the primary type of bone (which replaces woven bone)? |
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Definition
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Term
What inhibits resorption of calcium? |
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Definition
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Term
What stimulates resorption and calcium release in bone tissue? |
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Definition
The Parathyroid gland hormone (PTH) |
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Term
What percent of the calcium reservoir is found in the skeleton? |
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Definition
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Term
Which of the support cells of the nervous system is involved in moving CSF? |
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Definition
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Term
Which nervous system support cells produce myelin sheaths around axons to provide electircal insulation? |
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Definition
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Term
Which nervous system support cells are the most numerous glial cells in CNS and function as regulators? |
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Definition
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Term
Retrograde transport refers to the transport of materials where? |
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Definition
From axon TO THE CELL BODY |
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Term
Anterograde transport refers to transport from where? |
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Definition
FROM THE CELL BODY through the axon |
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Term
Nervous components such as sensory neurons that recieve stimuli are.....? |
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Definition
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Term
Nervous components such as motor neurons which send impulses are....? |
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Definition
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Term
Which layer of meninges acts as a cushion? |
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Definition
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Term
What three connevtive tissue layers covering the CNS make up the meninges? |
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Definition
Dura Mater, Arachnoid, and Pia Mater |
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Term
What functions to remove water from blood and release it as CSF? |
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Definition
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Term
What are the three main components of the peripheral nervous system? |
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Definition
nerves, ganglia, and nerve endings |
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Term
What are the major regions of the Central Nervous System? |
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Definition
Cerebrum, Cerebellum, and Spinal Cord |
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Term
A sarcomere is a subunit of muscle measuring from what? |
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Definition
Z disc to the next Z disc |
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Term
What are the three types of muscle tissue? |
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Definition
Skeletal, Cardiac, Smooth |
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Term
Skeletal muscles exhibits light and dark bands called... |
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Definition
A bands, I bands, and Z disc |
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Term
What is folded into the T tubules of muscle cells? |
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Definition
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Term
What enzyme supplies ATP to muscle? |
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Definition
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Term
The role of myoglobin in muscle is to provide... |
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Definition
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Term
Why does cartilage exhibit slow repair? |
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Definition
Because it is avascular, containing no blood vessels. |
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Term
What are the steps of muscle contraction? |
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Definition
1.Aceytlcholine is released from neuron to cause calcium release in muscle.
2. Calcium binds troponin to cause tropomyosin to move actin revealing action sites.
3. Mysosin binds to actin and changes shape to pull actin (requires ATP).
4. Calcium is reabsorbed to end contraction by tropomyosin covering actin. |
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Term
What is the largest protein in the body? |
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Definition
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Term
Draw an action potential chart. |
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Definition
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Term
List one stimulatory and inhibitory neurotransmitter |
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Definition
Adenosine, GABA- inhibitory
Norepinephrine, Acetylcholine- stimulatory |
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Term
What is a neurotransmitter which can be both inhibitory and stimulatory? |
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Definition
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Term
What is a neurotransmitter which can be both inhibitory and stimulatory? |
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Definition
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Term
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Definition
Influences muscle tone and opens and closes various ion channels |
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