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Essentials of Nutrition
Final Exam
215
Health Care
Undergraduate 3
04/07/2009

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Term
Trace minerals
Definition
essential mineral nutrients found in the human body in amounts smaller than 5g; sometimes called MICROminerals
Term
mucosa
Definition
mucous membrane such as the one that lines the GI tract
Term
Myoglobin
Definition
oxygen-holding protein of the muscle cells
Term
ferritin
Definition
iron storage protein
Term
transferrin
Definition
iron transport protein
Term
heme
Definition
iron-holding part of the hemoglobin and myoglobin and myoglobin proteins. About 40% of the iron in meat, fish, and poultry is bound to heme; the other 60% is nonheme iron
Term
MFP Factor
Definition
a peptide released during the digestion of Meat, Fish, and Poultry (MFP) that enhances nonheme iron absorption.
Term
hemosiderin
Definition
an iron-storage protein primarily made in times of iron overload
Term
hepcidin
Definition
a hormone produced by the liver that regulates iron balance
Term
iron deficiency
Definition
the state of having depleted iron stores
Term
iron-deficiency anemia
Definition
severe depletion of iron stores that results in low hemoglobin and small, pale red blood cells. Anemias that impair hemoglobin synthesis are microcytic (small cell)
Term
erythrocyte protoporphyrin
Definition
a precursor to hemoglobin
Term
hematocrit
Definition
measurement of the volume of the red blood cells packed by centrifuge in a given volume of blood
Term
pica
Definition
a craving for nonfood substances. Also known as geophagia when referring to clay eating and pagophagia when referring to ice craving
Term
iron overload
Definition
toxicity from excess iron
Term
hemochromatosis
Definition
a genetically determined failure to prevent absorption of unneeded dietary iron that is characterized by iron overload and tissue damage
Term
hemosiderosis
Definition
a condition characterized by the deposition of hemosiderin in the liver and other tissues
Term
contamination iron
Definition
iron found in foods as the result of contamination by inorganic iron salts from iron cookware, iron-containing soils, and the like
Term
chelate
Definition
substance that can grasp the positive ions of a mineral; chele = claw
Term
metalloenzymes
Definition
enzymes that contain one or more minerals as part of their structures
Term
metallothionein
Definition
a sulfur-rich protein that avidly binds with and transports metals such as zinc
Term
enteropancreatic circulation
Definition
the circulatory route from the pancreas to the intestine and back to the pancreas
Term
goiter
Definition
an elargement of the thyroid gland due to an iodine deficiency, malfunction of the gland, or overconsumption of goitrogen. Goiter casued by iodine deficiency is "simply goiter"
Term
goitrogen
Definition
a substance that enlarges the thyroid gland and causes toxic goiter. Goitrogens occur naturally in such foods as cabbage, kale, brussels sprouts, cauliflower, broccoli, and kohlrabi.
Term
crentinism
Definition
a congential disease characterized by mental and physical retardation and commonly caused by maternal iodine deficiency during pregnancy.
Term
selenium
Definition
a trace element
Term
fluorapatite
Definition
the stabilized form of bone and tooth crystal, in which flouride has replaced the hydroxyl groups of hydroxyapatite
Term
fluorosis
Definition
discoloration and pitting of tooth enamel caused by excess flouride during tooth development
Term
heavy metals
Definition
mineral ions such as mercury and lead, so called b/c they are of relatively high atomic weight. Many are poisonous.
Term
flexibility
Definition
the capacity of the joints to move through a full range of motion; the ability to bend and recover without injury
Term
muscle strength
Definition
the ability of muscles to work against resistance
Term
muscle endurance
Definition
the ability of a muscle to contract repeatedly without becoming exhausted
Term
cardiorespiratory endurance
Definition
the ability to perform large-muscle, dynamic exercise of moderate-to-high intensity for prolonged periods
Term
conditioning
Definition
the physical effect of training; improved flexibility, strength, and endurance
Term
training
Definition
practicing and activity regularly, which leads to conditioning.
Term
progressive overload of principle
Definition
the training principle that a body system, in order to improve, must be worked at frequencies, durations, or intensisties that gradually increase physical demands
Term
frequency
Definition
the number of occurrences per unit of time (number of activity sessions per week)
Term
intensity
Definition
the degree of exertion while exercising
Term
duration
Definition
length of time
Term
hypertrophy
Definition
growing larger; with regard to muscles, an increase in size (and strength) in response to use
Term
atrophy
Definition
becoming smaller; with regard to muscles, b/c of disuse, undernutrition, or wasting disease
Term
warm-up
Definition
5 to 10 minutes of light activity
Term
cool-down
Definition
5 to 10 minutes of light activity to gradually return the body's core temp to near-normal
Term
moderate exercise
Definition
activity equivalent to the rate of exertion reached when walking at a speed of 4 mph
Term
VO2max
Definition
maximum rate of oxygen consumption by an individual at sea level
Term
cardiorespiratory conditioning
Definition
improvements in heart and lung function and increased blood volume brought about by aerobic training
Term
cardiac output
Definition
the volume of blood discharged by the heart each minute; determinded by multiplying the stroke volume by the heart rate.
Term
weight training
Definition
(also called resistance training) the use of free weights or weight machines to provide resistance for developing muscle strength and endurance.
Term
CP, Creatine Phosphate
Definition
(also called phosphocreatine) a high-energy compouond in muscle cells that acts as a reservoir of energy that can maintain a steady supply of ATP. CP provides the energy for short bursts of activity.
Term
carbohydrate loading
Definition
a regimen of moderate exercise followed by the consumption of a high-carbohydrate diet that enables muscles to store glycogen beyond their normal capacities
Term
sports anemia
Definition
transient condition of low hemoglobin in the blood, associated with the early stages of sports training or other strenuous activity
Term
hyperthermia
Definition
an above-normal body temperature
Term
heat stroke
Definition
a dangerous accumulation of body heat with accompanying loss of body fluid
Term
hypothermia
Definition
below-normal body temp
Term
hourly sweat rate
Definition
the amount of weight lost plus fluid consumed during exercise per hour
Term
hyponatremia
Definition
a decreased concentration of sodium int he blood
Term
glucose polymers
Definition
compounds that supply glucose, not as single molecules, but linked in chains somewhat like starch. Objective is to attract less water from bod into digestive tract
Term
sulfate
Definition
oxidized form of sulfur
Term
sulfur
Definition
mineral present in body as part of some proteins
Term
magnesium
Definition
a cation within the body's cells, active in many enzyme systems
Term
phosphorus
Definition
a major mineral found mostly in the body's bones and teeth
Term
osteoporosis
Definition
a disease in which bones become porous and fragile due to loss of minerals
Term
calcium-binding protein
Definition
a protein in the intestinal cells, made with the help of vitamin D, that facilitates calcium absorption
Term
peak bone mass
Definition
the highest attainable bone density for an individual, developed during first three decades of life
Term
parathyroid hormone
Definition
a hormone that regulates blood calcium by raising it when levels fall to low
Term
calcitonin
Definition
a hormone secreted by the thyroid gland that regulates blood calcium by lowering it when levels rise too high
Term
calcium rigor
Definition
hardness or stiffness of the muscles casued by high blood calcium levels
Term
calcium tetany
Definition
intermittent spasm of the extremities due to nervous and muscular excitability caused by low blood calcium concentrations
Term
calcium
Definition
the most abundant mineral in the body; found primarily int he body's bones and teeth
Term
hydroxyapatite
Definition
crystals made of calcium and phosphorus
Term
mineralization
Definition
the process in which calcium, phosphorus, and other minerals crystallize on the collagen matrix of a growing bone, hardening the bone
Term
potassium
Definition
the principal cation within the body's cells; critical to the maintenance of fluid balance, nerve impulse transmissions, and muscle contractions
Term
chloride
Definition
the major anion in the extracellular fluid of the body.
Term
sodium
Definition
principal cation in the extracellular fluids; critical to the maintenance of fluid balance, nerve impulse transmissions, and muscle contractions
Term
salt sensitivity
Definition
respond to high salt intake with an increase in blood pressure or to a low salt intake with a decrease in blood pressure
Term
binders
Definition
chemical compounds in foods that combine with nutrients to form complexes the body cannot absorb. EX: phytates and oxalates
Term
major minerals
Definition
essential mineral nutrients found in the human body in amounts larger than 5g; called MACROminerals
Term
carbonic acid
Definition
H2CO3 -important in maintaining the body's acid-base balance
Term
solutes
Definition
the substances that are dissolved in a solution
Term
osmosis
Definition
the movement of water across a membrane toward the side where solutes are more concentrated
Term
osmotic pressure
Definition
the amount of pressure needed to prevent the movement of water across a membrane
Term
salt
Definition
compound composed of positive ion other than H+ and a negative ion other than OH
Term
ions
Definition
atoms or molecules that have gained or lost electrons and therefore have electrical charges.
Term
cations
Definition
positively charged ions
Term
anions
Definition
negatively charged ions
Term
electrolytes
Definition
salts that dissovle in water and dissociate into charged particles called ions
Term
electrolyte solutions
Definition
solutions that can conduct eletricity
Term
milliequivalents (mEq)
Definition
The concentration of electrolytes in a volume of solution
Term
renin
Definition
an enzyme from the kidneys that activates angiotensin
Term
angiotensin
Definition
a hormone involved in blood pressure regulation; activated by renin (an enzyme from kidneys)
Term
vasoconstrictor
Definition
a substance that constricts or narrows the blood vessels
Term
aldosterone
Definition
a hormone secreted by the adrenal glands that regulates blood pressure by increasing the reabsorption of sodium by the kidneys.
Term
adrenal glands
Definition
glands adjacent to, and just above, each kidney
Term
water balance
Definition
the balance b/t water intake and losses
Term
intracellular fluid
Definition
fluid within the cells, usually high in potassium and phosphate. Accounts for 2/3's of body's water
Term
interstitial fluid
Definition
fluid between cells, usually high in sodium and chloride.
Term
extracellular fluid
Definition
fluid outside cells. 2 main components: interstitial fluid and plasma. Accounts for 1/3 of body's water
Term
dehydration
Definition
condition in which body water output exceeds water input. Symptoms: thrist, dry skin and muscous membranes, rapid heartbeat, low blood pressure, and weakness.
Term
water intoxication
Definition
rare condition in which body water contents are too high in all body fluid compartments
Term
hemorrhagic disease
Definition
a disease characterized by excessive bleeding
Term
hemophilia
Definition
a hereditary disease in which the blood is unable to clot b/c it lacks the ability to synthesize certain clotting factors.
Term
sterile
Definition
free of microorganisms, such as bacteria
Term
alpha-tocopherol
Definition
the active vitamin E compound
Term
erythrocyte hemolysis
Definition
breaking open of red blood cells; a symptom of vitamin E deficiency disease
Term
muscular dystrophy
Definition
a hereditary disease in which the muscles gradually weaken (most debilitating in lungs)
Term
fibrocystic breast disease
Definition
harmless condition in which the breasts develop lumps
Term
intermittent claudication
Definition
severe calf pain caused by inadequate blood supply
Term
tocopherol
Definition
a general term for several chemically related compounds, one of which has vitamin E activity
Term
ricktes
Definition
vitamin D deficiency disease in children characterized by inadequate mineralization of bone (bowed legs or knock-knees)
Term
osteomalacia
Definition
a bone disease characerized by softening of bones. Symptoms: bending of spine and bowing of legs (most often in adult women)
Term
chlorophyll
Definition
green pigment of plants, which absorbs light and transfers the enery to other molecules, initiating photosynthesis
Term
xanthophylls
Definition
pigments found in plants; responsible for color changes seen in autumn leaves
Term
preformed vitamin A
Definition
dietary vitamin A in its active form
Term
teratogenic
Definition
causing abnormal fetal development and birth defects
Term
acne
Definition
chronic inflammation of skin's follicles and oil-producing glands
Term
retinol activity equivalents (RAE)
Definition
measure of vitamin A activity; the amount of retinol that the body will derive from a food containing preformed retinol or beta-carotene
Term
night blindness
Definition
slow recovery of vision after flashes of bright light at night or an inability to see in dim light (vitamin A deficiency)
Term
xerophthalmia
Definition
progressive blindness caused by severe vitamin A deficiency
Term
xerosis
Definition
abnormal drying of the skin and mucous membranes (vitamin A def)
Term
keratomalacia
Definition
softening of the cornea that leads to irreversible blindness (vitamin A def)
Term
keratin
Definition
a water-insoluble protein in hair and nails
Term
keratinizaiton
Definition
accumulation of keratin in a tissue (vitamin A def)
Term
cornea
Definition
transparent membrane covering the outside of eye
Term
retina
Definition
layer of light-sensitive nerve cells lining the back of the inside of the eye; consists of rods and cones
Term
pigment
Definition
molecule capable of absorbing certain wavelengths of light so that it reflects only those that we perceive as a certain color
Term
rhodopsin
Definition
light-sensitive pigment of the retina; contains the retinal form of vitamin A and the protein opsin
Term
opsin
Definition
the protein portion of the visual pigment molecule
Term
cell differentiation
Definition
process by which immature cells develop specific functions different from those of the original that are characteristic of their mature cell type
Term
epithelial cells
Definition
cells on the surface of the skin and mucous membranes
Term
retinol-binding protein (RBP)
Definition
specific protein responsible for transporting retinol
Term
Vitamin A
Definition
all naturally occurring compounds with the biological activity of retinol, the alcohol form of vitamin A
Term
beta-carotene
Definition
one of the carotenoids; an orange pigment and vitamin A precursor found in plants
Term
carotenoids
Definition
pigments found in plants and animals, some of which have vitamin A activity.
Term
retinoids
Definition
chemically related compounds with biological activity similar to retinol; metabolites of retinol
Term
false positive
Definition
a test result indicating that a condition is present when in fact it is not
Term
false negative
Definition
test result indicating that a condition is NOT present when in fact it is present
Term
histamine
Definition
a substance produced by cells of the immune system as part of local immune reaction to an antigen; causes inflammation
Term
antiscorbutic factor
Definition
the original name for vitamin C
Term
ascorbic acid
Definition
one of the two active forms of vitamin C
Term
antioxidant
Definition
substance in foods that significantly decreases the adverse effects of free radicals on normal physiological functions in the human body
Term
free radicals
Definition
unstable molecules with one or more unpaired electrons
Term
oxidative stress
Definition
a condition in which the production of oxidants and free radicals exceeds the body's ability to handle them and prevent damage
Term
inositol
Definition
a nonessential nutrient that can be made in the body form glucose; a part of cell membrane structures
Term
carnitine
Definition
a nonessential, nonprotein amino acid made in the body from lysine that helps transport fatty acids across the mitochondrial membrane
Term
intrinsic factor
Definition
a glycoprotein secreted by the stomach cells that binds with vitamin B12 in the small intestine to aid in the absorption of B12
Term
atrophic gastritis
Definition
chronic inflammation of the stomach accompanied by a diminished size and functioning of the mucous membrane glands
Term
pernicious anemia
Definition
a blood disorder that reflects a B12 deficiency caused by lack of intrinsic factor and characterized by abnormally large and immature red blood cells; symptoms: muscle weakness & irreversible neurological damage
Term
anemia
Definition
"too little blood" too few red blood cells are present or too immature
Term
folate
Definition
B Vitamin; also known as folic acid, folacin; pregnant women
Term
dietary folate equivalents (DFE)
Definition
amount of folate available to the body from naturally occurring sources, fortified foods, and supplements
Term
neural tube defects
Definition
malformations of the brain, spinal cord, or both during embryonic development that often result in lifelong disability/death
Term
neural tube
Definition
the embryonic tissue that forms the brain and spinal cord
Term
antagonist
Definition
competing factor that counteracts the action of another factor. Ex: drugs render vitamins ineffective
Term
carpal tunnel syndrome
Definition
pinched nerve at the wrist, causing pain or numbness int eh hand.
Term
pantothenic acid
Definition
B Vitamin, "CoA" -coenzyme A
Term
biotin
Definition
B vitamin that functions as a coenzyme in metabolism
Term
niacin flush
Definition
temporary burning, tingling, and itching sensation that occurs when a person takes a large does of nicotinic acid; headache, reddened face arms, and chest
Term
pellagra
Definition
the niacin-deficiency disease, rough skin
Term
riboflavin
Definition
B Vitamin, energy metabolism
Term
beriberi
Definition
thiamin-deficiency disease - "I can't, I can't" -weakness
Term
bioavailability
Definition
the rate at and the extent to which a nutrient is absorbed and used
Term
precursors
Definition
substnaces that precede others; with regard to vitamins, provitamins
Term
orlistat
Definition
a drug used in the treatment of obesity that inhibits the absorption of fat in the GI tract, thus limiting kcaloric intake
Term
sibutramine
Definition
a drug used in the treatment of obesity that slows the reabsorption of serotonin in the brain, thus suppressing appetite and creating a feeling of fullness
Term
clinically severe obesity
Definition
a BMI of 40 or greater or a BMI for 35 with additional medical problems.
Term
serotonin
Definition
a neurotransmitter important in sleep regulation, appetite control, and sensory perception; synthesized from amino acid tryptophan with the help of B6
Term
brown adipose tissue
Definition
masses of specialized fat cells packed with pigmented mitochondria that produce heat instead of ATP
Term
gene pool
Definition
all the genetic information of a population at a given time
Term
ghrelin
Definition
a protein produced by the stomach cells that enhances appetite and decreases energy expenditure
Term
leptin
Definition
a protein produced by fat cells under direction of the "ob" gene that decreases appetite and increases energy expenditure sometiems called the "Ob protein" -leptos = "thin"
Term
epidemic
Definition
appearance of a disease (usually infectious) or condition that attacks many people at the same time in the same region
Term
set point
Definition
the point at which controls are set; the theory that relates to body weight, the weight the body tends to maintain by its won internal controls
Term
weight management
Definition
maintaining body weight in a healthy range by preventing gradual weight gain over time
Term
insulin resistance
Definition
the condition in which a normal amount of insulin produces a subnormal effect in muscle, adipose, and liver cells, resulting in an elevated fasting glucose
Term
inflammation
Definition
an immunological response o cellular injury characterized by an increase in white blood cells
Term
waist circumference
Definition
an anthropometric measurement used to assess a person's abdominal fat
Term
intra-abdominal fat
Definition
fat stored within the abdominal cavity in association with the internal abdominal organs, as opposed to fat stored directly under the skin (subcutaneous fat)
Term
central obesity
Definition
excess fat around the trunk of body, also called abdominal fat or upper-body fat
Term
Body Mass Index (BMI)
Definition
index of a person's weight in relation to height; determined by dividing the weight (in kg) by the square of the height (in meters)
Term
underweight
Definition
BMI below 18.5
Term
overweight
Definition
BMI 25 to 29.9
Term
obese
Definition
BMI of 30 or higher
Term
body composition
Definition
the proportions of muscle, bone, fat, and other tissue that make up a person's total body weight
Term
thermic effect of food (TEF)
Definition
an estimation of the energy required to process food
Term
adaptive thermogenesis
Definition
adjustments in energy expenditure related to changes in environment such as extreme cold and to physiological events such as overfeeding, trauma, and changes in hormone status
Term
basal metabolism
Definition
energy needed to maintain life when a body is at complete digestive, physical, and emotional rest
Term
basal metabolic rate (BMR)
Definition
rate of energy use for metabolism under specified conditions: after 12 hour fast and restful sleep, w/o any physical activity or emotional excitement.
Term
resting metabolic rate (RMR)
Definition
less stringent criteria than BMR( in regards to food/activity) -slightly higher than BMR
Term
neuropeptide Y
Definition
a chemical produced in the brain that stimulates appetite, diminishes energy expenditure, and increases fat storage
Term
thermogenesis
Definition
the generation of heat; used in physiology and nutrition studies as an index of how much energy the body is expending
Term
satiating
Definition
having the power to suppress hunger and inhibit eating
Term
hypothalamus
Definition
a brain center that controls activities such as maintenance of water balance, regulation of body temp, and control of appetite
Term
bomb calorimeter
Definition
an instrument that measures the heat energy released when foods are burned, thus providing an estimate of the potential energy of the foods
Term
oxaloacetate
Definition
a carbohydrate intermediate of the TCA cycle
Term
urea
Definition
the principal nitrogen-excretion product of protein metabolism. Two ammonia fragments are combined with CO2 to form this
Term
keto acid
Definition
organic acid that contains a carbonyl group
Term
ammonia
Definition
chemical formula NH3; produced during the deamination of amino acids
Term
transamination
Definition
the transfer of an amino group from one amino acid to a keto acid, producing a new nonessential amino acid and a new keto acid
Term
fatty acid oxidation
Definition
the metabolic breakdown of fatty acids to acetyl CoA; also alled beta oxidation
Term
lactate
Definition
3-carbon compound produced from pyruvate during anaerobic metabolism
Term
Cori cycle
Definition
path from muscle glycogen to glucose to pyruvate to lactate (to liver) to glucose to glycogen
Term
anaerobic
Definition
not requiring oxygen
Term
mitochondria
Definition
cellular organelles responsible for producing ATP; made of membranes (lipid and protein) with enzymes mounted on them
Term
glycolysis
Definition
the metabolic breakdown of glucose to pyruvate. Does NOT require oxygen (anaerobic)
Term
pyruvate
Definition
3-carbon compound that plays a key role in energy metabolism
Term
acetyl CoA
Definition
2-carbon compound to which a molecule of CoA is attached
Term
CoA
Definition
coenzyme derived from the B vitamin pantothenic acid and central to energy metabolism
Term
electron transport chain
Definition
final pathway in energy metabolism that transports electrons from hydrogen to oxygen and captures the energy released in the bonds of ATP
Term
catabolism
Definition
reactions in which large molecules are broken down to smaller ones -release energy
Term
ATP
Definition
common high-energy compound composed of a purine(adenine), sugar, and 3 phosphate groups
Term
coupled reactions
Definition
pairs of chemical reactions in which some of the energy released from the breakdown of one compound is used to create a bond in the formation of another compound
Term
coenzymes
Definition
complex organic molecules that work with enzymes to facilitate the enzymes' activity. many have B vitamins as part of structures
Term
photosynthesis
Definition
process by which green plants use the sun's energy to make carbs from CO2 and water
Term
fuel
Definition
compounds that cells can use for energy. Major fuels include: glucose, fatty acids, and amino acids
Term
metabolism
Definition
sum total of all the chemical reactions that go on in living cells.
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