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Exam 2
Equine Skin Tumors
46
Veterinary Medicine
Professional
10/07/2016

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Cards

Term
What is the most common site for tumors in horses?
Definition
-skin
Term
What are the 4 most common skin tumors in horses?
Definition
-sarcoid
-squamous cell carcinoma
-melanoma
-papilloma
Term
What is the single most common skin tumor in the horse?
Definition
-sarcoid
Term
What is the age group of horses affected by sarcoids?
Definition
-all ages
Term
What is the etiolgy behind sarcoids?
Definition
-viral!
-atypical response to a wound or injury
Term
What are the clinical features of each type of an equine sarcoid?
Definition
-Verrucous: warty like
-Gibroblastic: raw, granulomatous mass
-Mixed: duh
-Occult: flat, scaley
Term
What are the differentials for a fibroblastic type sarcoid?
Definition
-EGT
-SCC
-Habronema
Term
What diagnostics do we run on a sarcoid?
Definition
-biopsy!!! then thorough surgical excision
Term
What are our treatment options for equine sarcoids?
Definition
-surgical excision
-surgical ablation
-sryotherap
-chemotherapy
-immunotherapy
Term
What is you very first step of treating an equine sarcoid?
Definition
-debulk first!!!
Term
Describe the process of cryotherapy when applied to an equine sarcoid.
Definition
-tumor first debulked
-control hemorrhage
-tumor is frozen! 3 freeze-thaw cycles
Term
Describe the process of immunotherapy when applied to an equine sarcoid.
Definition
-injected into and around the tumor
-applied topically
Term
For what types of tumors do we use BCG?
Definition
-BCG = BAcillum Salmette-Guerin
-effective on tumors on the head
Term
How do we apply Imiquimod for immunotherapy of equine sarcoids?
Definition
-topically
Term
How do we apply blood root extract for immunotherapy of equine sarcoids?
Definition
-topically
Term
How do we apply chemotherapy to an equine sarcoid?
Definition
-injected into and around the tumor
-applied topically
Term
How is Carboplatin used as a chemotherapy agent for the treatment of equine sarcoids?
Definition
-injected with sesame oil as a carrier
Term
How is Cisplatin applied as a chemotherapy for equine sarcoids?
Definition
-as beads (marix III) absorbed in 30 days
Term
How is 5FU applied as a chemotherapy for equine sarcoid?
Definition
-topical or intratumoral
Term
What is the prognosis for equine sarcoids?
Definition
-location dependent
-head, trunk, upper limbs = good
=-distal limbs = guarded
Term
What are the primary concerns with client educaiton regarding equine sarcoids?
Definition
-treatment can be expensive
-multiple treatments necessary
-recurrence likely
Term
What is the typical signalment of SCC in horses?
Definition
-no predilection
-usually seen in older horses: 12 yo
Term
What is the typical etiology of SCC?
Definition
-UV light onnon-pigmented/hairless regions
Term
What are the most common locations of SCC?
Definition
=head and genitalia
Term
How do SCC commonly appear?
Definition
-ulcerative or granulomatous
Term
Do SCC's metastasize? Expound.
Definition
-They DO metastasize: locally invasive
-head = invade the skull
-penis/prepuce = regional LN
Term
What is the primary diagnostic test we run of SCCs?
Definition
-biopsy!!!
Term
What are the treatment options for SCCS?
Definition
-surgical excision
-surgical ablation
-cryotherapy
-chemotherapy
Term
How do we manage a small localized SCC on the genitalia?
Definition
-laser ablation
-topical chemotherapy: 5FU
-surgical excision
Term
How do we manage SCC that has extensive involvement?
Definition
-radical surgical excision
Term
What is the prognosis of SCC?
Definition
-localized = fair - good
-metastasis = poor
Term
What is the primary concern for client education regarding SCC?
Definition
-rechecks necessary
Term
What is the typical signalment for equine melanoma?
Definition
-grey horses
-more common in older horses
Term
What are the common locations for melanomas?
Definition
-perineum
-undersurface of tail
-pinnae
Term
What are the common clinical features of melanoma?
Definition
-appear as firm intradermal or subcutaneous nodule(s)
-may on occasion become ulcerated
Term
Are most melanomas benign or malignant?
Definition
-most develop as a benign tumor but may become malignant
Term
What are the possible characteristics of equine sarcoids?
Definition
-slow growth no metastasis (benign)
-slow groth then rapid growth and malignancy
-rapid growth and malignancy
Term
How do we typically diagose melanoma in a horse?
Definition
-visual rpesentation
-biopsy yes but may become more active
Term
What are our therapeutic options for equien melanoma?
Definition
-ignore
-surgical, laser excision, ablation if small solitary mass
-cryotherapy
-chemotherapy
-cimetidine
Term
What is the primary concern with client education regarding equine melanomas?
Definition
-unless tumor(s) is interfering with function, benign treatment is the wisest
Term
What is the typical signalment of papillomas in horses?
Definition
-young horses
Term
What is the etiology behind papillomas? Incubation period?
Definition
-Equine papilloma virus
-2-6 months
Term
What is the typical location of papillomas in the horse?
Definition
-muzzle
Term
How are equine papillomas usually diagnosed?
Definition
-clinical features but biopsy
Term
HOw do we treat equine papillomas?
Definition
-do nothing: usually spontaneously regress in 1-6 months
-surgical excision, cryotherapy, hyperthermia, autogenous vx
-ISOLATE
Term
Absorption of serum by a graft soon after transplanting is called what?
Definition
-serum imbibition
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