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Equine Protein Metabolism And Requirements
Equine Protein Metabolism And Requirements
27
Nutrition
Undergraduate 4
02/25/2015

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Term
True or False

The horse has no dietary requirement for protein
Definition
true

(but does require essential AAs)
Term
True or False

Grains, by-products & fibrous materials are often insufficient in meeting a horse's protein requirements
Definition
true
Term
What is the major body store for essential AAs?
Definition
contractile protein (in muscle)
Term
What is the most labile pool of AAs?
Definition
blood proteins
Term
In a short-term state of dietary protein deficiency, what will be the primary source of protein?
Definition
blood proteins
Term
Why is immunosuppression associated with protein deficiency?
Definition
mobilization of immunoglobulins & reduced synthesis of immune proteins will inhibit the function of the immune system
Term
What are the dietary essential AAs?
Definition
Arg
His
Val
Trp
Thr
Leu
Lys
Iso
Phe
Met
Term
What two AAs are essential for neonates?
Definition
His & Arg as they cannot synthesize adequate amounts
Term
What amino acid is key in forming cross-linkages in structural proteins of the body?
Definition
lysine
Term
A deficiency of what AA might lead to compromised mechanical strength of the horse?
Definition
lysine
Term
Why does N balance improve with conditioning?
Definition
reduced urinary N loss due to improved N retention & increased muscle mass resulting from muscle hypertrophy
Term
True or False

The equine large colon can uptake more lysine than the jejunum
Definition
true
Term
True or False

Cereal grains such as corn, oats, barely & wheat are excellent sources of lysine
Definition
false
Term
What are the best sources of lysine?
Definition
fish meal
dried brewer's yeast
soybean meal
dried skim milk
Term
Ensuring the diet has adequate amounts of ______ can reduce the need for methionine
Definition
cystine
Term
Ensuring the diet has adequate amounts of ______ can reduce the need for phenylalanine
Definition
tyrosine
Term
What happens to the nitrogen produced from catabolism of excess AAs?
Definition
excreted as urea (requires energy)
Term
What is the second limiting dietary AA for yearling horses on a forage-based diet?
Definition
threonine
Term
How does catabolism of branched-chain AAs different from other AAs?
Definition
deamination takes place in muscle
Term
What is the glucose-alanine cycle?
Definition
BCAA are deaminated in muscle
Alanine receives the resulting amino group
Alanine is carried to liver for urea synthesis
Glucose is transferred back to muscle
Term
Which BCAA is best at promoting nitrogen retention?
Definition
leucine
Term
How does leucine promote muscle protein retention?
Definition
degradation of leucine produces a metabolite which lowers the pH of lysosomes, reducing catabolic activity of cathepsins which degrade proteins
Term
What regulates feed intake?
Definition
energy density of the feed
Term
How might you use non-protein nitrogen in the diet to meet protein requirements? For what type of horse is this viable?
Definition
urea can act as a N source for microbes in the cecum, producing some AAs

useful for mature horses requiring maintenance, on a low-protein diet
Term
At what stage of pregnancy do protein requirements increase?
Definition
last trimester
Term
What is the issue with melamine & protein levels in feed?
Definition
melamine is 66.64% nitrogen, skews protein calculations based on N content, making the protein levels appear higher than they truly are

melamine is toxic
Term
What is dietary protein used for?
Definition
synthesis of muscle
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