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present at birth relatively non-specific natural barriers of animal (ex. skin) mucous membrane cellular actions antibody production |
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specific immunity against a foreign agent |
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the animal has gotten a specific immunity against an agent for a specific infection Natural-naturally actually infected Artificial-vaccines/shots |
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actually produce antibodies |
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do not produce antibodies, but are turn on for B-cells |
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monocytes - kick started by T-cells |
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not making it ourselves given to animal somehow ex. mare's milk |
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injections of hyper-immune serum |
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DEFENSIVE MECHANISMS: PRIMARY |
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skin & mucous membranes body secretions on the skin (ex. sweat) pH of secretions help prevent MOs respiratory secretions & functions lymphatic system tissue fluids inflammation fever |
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DEFENSE MECHANISMS: SECONDARY |
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phagocytosis: ingesting and destroying foreign particles WBC: granulocytes, monocytes |
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inflammation: mobilization of WBC due to chemical release ingestion of bacteria destroying of bacteria |
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neutrophils: 1st response attract other cells eosinophils: very attracted to histamine, allergic reaction monocytes: really big killer cells |
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DEFENSE MECHANISMS: TERTIARY |
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B lymphocytes: produce antibodies T lymphocytes: turn on reaction, activate B cells and other phagocytic cells |
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clotting, inflammatory proteins |
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plasma-clotting factors, organ secretion, minerals, enzymes |
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leukocytes: comes from bone marrow |
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killer cells bacterial infections "segs" mature "bands" immature |
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allergies hypersensitivity inflammatory |
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histamine allergic reaction, injury sites, GI tract, skin and lungs |
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(S)CID foals do not have these "smart bombs" B-cells/t-cells can live for weeks/years |
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largest cells last to show up a lot present during long term illness "killer cells" |
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COMPLETE BLOOD COUNT (CBC) |
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red blood cells(RBC)- 7-12 million/cc packed cell volume(PCV)- cells (34-50%) vs plasma(remaining) Hemoglobing- 11-19g/100 ml of blood white blood cells (WBC)- 8,000-11,000 cells/cc |
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produced by B-cells-immunoglobulins IgG-70% of all antibodies IgM-10% of all antibodies, 1st Ig produced in an immune response then IgGs take over IgA-15-20% of serum antibodies IgD-less than 1% of antibodies, in membranes of lymphocytes to help differentiation IgE- less than 1% of antibodies, functions in immune response to parasites, on surface of basophils IgE- functions in immune response to parasites |
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adjuvant: help preserve the vaccine along w/ refrigeration, carrying solution, modified organism is weaker, trigger response in animal to make antibodies |
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organism is dead but response to it will still create antibodies against organisms |
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