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Epidemiology
Final Review for Epidemiology for MPH
47
Health Care
Graduate
12/07/2012

Additional Health Care Flashcards

 


 

Cards

Term
Attack Rate
Definition
People who became ill/all people who ate that food
Example: Cole Slaw
Total of 50 people ate it, 9, became sick, 41 did not.
Attack rate for cole slaw is 9/50=.18x100=18%
Term
Attack Ratio
Definition
Attack rate in Exposed/ Attack rate in Unexposed
Term
Passive Immunity
Definition
Antibodies are injected for short-term protection (like in Rabies)
Term
Active Immunity
Definition
Stimulating the body's own antibody production for long-term protection (like in Tetanus)
Term
Herd Immunity
Definition
Provides protection when 70-90% of the population are vaccinated.
Term
Incubation Period
Definition
Interval from time of exposure to the onset of symptoms
Term
Carrier status
Definition
Individuals harbor the organism but aren't infected and are asymptomatic
Term
isolation
Definition
separate ill people who have a communicable disease from those who are healthy
Term
quarantine
Definition
separate people who are not yet ill but who have been exposed
Term
propagated epidemic
Definition
person-to-person exposure
Term
point epidemic
Definition
people exposed to same source over a brief period of time
Term
Primary Prevention
Definition
Prevention of the disease from ever occurring. Examples: immunization for flu, education.
Term
Secondary Prevention
Definition
Identifies and treats asymptomatic persons who already have developed risk factors or the disease, but don't know they have it. Example: stool sample for prostate cancer.
Term
Tertiary Prevention
Definition
Attempts made to restore to highest function and minimize disability in people that already have the disease. Example: dialysis for kidney failure
Term
Prevalence
Definition
number of cases/total persons in the population
Term
What does prevalence measure?
Definition
Buden of the disease.
Term
Point Prevalence
Definition
number of cases at a specific point in time/total number of people in the population at that specific point in time.
Term
Period Prevalence
Definition
number of cases over a period of time/total number of people int he population at that specific point in time.
Term
Cumulative Incidence
Definition
number of new cases/total number of people at risk for disease
Term
Incidence Density
Definition
number of new cases/sum of the different times each person was a risk
Term
What does incidence measure?
Definition
Risk of getting the disease.
Term
Crude mortality rate
Definition
total number of deaths/total population
Term
Disease Specific Mortality Rate
Definition
Total number of deaths from a specific disease during a period of time/total population
Term
Cae reports and case series
Definition
Descriptive studies that:
-describe a patients illness and symptoms
-suggest new diseases and epidemics
-don't have a comparison group, can't test hypothesis
Term
Cross-sectional studies
Definition
Descriptive studies that:
-also known as prevalence studies
-look at both disease and exposure at the same time
-can calculate prevalence from
-good for chronic diseases
-cheap
-don't establish a temporal relationship
Term
Ecological Studies
Definition
Descriptive studies that:
-group is the unit of analysis
-Example is phone and breast cancer use
Term
Case-Control Studies
Definition
-inexpensive
-Good for rare diseases
-Good for chronic diseases
-Can determine OR
Term
Cohort Studies
Definition
-good for rare exposures
-multiple risk factors at same time
-multiple effects of a single exposure
-Determine incidence
-Determine causality
Term
Randomized Clinical trials
Definition
-participants are chosen based on their exposure status, and exposure status is assigned by the researcher.
-gold standard of studies
Term
Odds Ratio
Definition
-get it from Case control studies
OR<1: there is a negative association between exposure and disease.
OR>1: there is an association between exposure and disease
OR=1: No association
Term
Three types of Randomization for RCT's
Definition
simple, replacement, and stratified
Term
The 4 types of RCT Trials are:
Definition
Treatment, prevention, quality of life and screening trials
Term
Pragmatic Approach
Definition
Everyone is included in analysis, even non-compliant participants
Term
Explanatory Approach
Definition
only compliant participants are included in the analysis
Term
Sensitivity
Definition
Ability of a test to correctly identify those who have the disease
Term
Formula for Sensitivity
Definition
(TP/TP+FN)
Term
Specificity
Definition
Ability of the test to correctly identify those who do not have the disease
Term
Formula for Specificity
Definition
(TN/TN+FP)
Term
Two stage testing
Definition
A test on a population that does a worse test first, then takes all the positives from that test and does a better, more accurate test. It increases specificity and saves money
Term
Simultaneous testing
Definition
Doing two very accurate tests at the same time.
Good for sensitivity, but is expensive. Good for diseases that are hard to diagnose.
Term
Predictive Value
Definition
If the test results are positive in this patient, what is the probability that this patient has the disease? What percent of patients who test positive actually have the disease?
Term
Positive Predictive Value (PPV)
Definition
The proportion of individuals screened positively by the test who actually have the disease. The higher the prevalence of the disease, the higher the predictive value. TP/Total Positives
Term
Negative Predictive Value (NPV)
Definition
The proportion of individuals screened who test negative and don't have the disease. TN/total negatives
Term
Types of Selection Bias
Definition
Admission Bias, Prevention Bias, Non-response/Non-participation Bias
Term
Types of Information Bias
Definition
Recall Bias, Interviewer Bias, Misclassification Bias
Term
Confounding
Definition
After stratifying, you have different OR's from the original
Term
Interaction
Definition
After stratifying, you have different OR's in the stratum
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