Term
Epidemiology study design |
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Definition
1. Experimental studies or Clinical trial
2. Observational study |
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study factor is manipulated by the investigator. |
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no manipulation of study factor by the investigator 1. Descriptive versus Analytic 2. Retrospective versus Prospective |
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Epidemiologic study designs (Observational study) |
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1. Prospective or Cohort study
2. Retrospective or Case control study
3. Cross sectional or Prevalence study |
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1. DESCRIPTIVE EPIDEMIOLOGY
2. ANALYTIC EPIDEMIOLOGY |
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seeks to measure the frequency in which diseases occur or collect descriptive data on possible causal factors. |
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attempts to specify in more detail the causes of a particular disease” |
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- Descriptive: Most basic demographic studies |
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a. * cross-sectional (a snapshot;) |
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Analytical: Comparative studies testing an hypothesis. |
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A. * cohort (prospective; cause-and-effect relationship can be inferred) B.* case-control (retrospective; cause-and-effect relationship can be inferred) |
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Begins with an exposure (smokers and non-smokers) |
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Case-control (retrospective ) |
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Begins with outcome (cancer cases and healthy controls) |
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Examining the distribution of a disease in a population, and observing the basic features of its distribution in terms of time, place, and person. |
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Typical study design:DESCRIPTIVE EPIDEMIOLOGY |
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community health survey (approximate synonyms - cross-sectional study, descriptive study) |
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Testing a specific hypothesis about the relationship of a disease to a putative cause, by conducting an epidemiologic study that relates the exposure of interest to the disease of interest. |
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ANALYTIC EPIDEMIOLOGY Typical study designs: |
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THE THREE ESSENTIAL CHARACTERISTICS OF DISEASE WE LOOK FOR IN DESCRIPTIVE EPIDEMIOLOGY: |
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Changing or stable? Seasonal variation. Clustered (epidemic) or evenly distributed (endemic)? Point source or propagated. |
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Geographically restricted or widespread (pandemic)? Relation to water or food supply. Multiple clusters or one? |
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Age Socio-economic status Gender Ethnicity/Race Behavior |
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To undertake an analytic epidemiologic study you must first: |
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Know where to look Know what to control for Be able to formulate hypotheses compatible with laboratory evidence |
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THE THREE PHENOMENA ASSESSED IN ANALYTIC EPIDEMIOLOGY ARE: |
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Nutrients Poisons Allergens Radiation Physical trauma Microbes Psychological experiences |
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Genetic endowment Immunologic state Age Personal behavior |
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Crowding Atmosphere Modes of communication |
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phenomena in the environment that bring host and agent together, such as: Vector Vehicle Reservoir |
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Cohort study/Incidence study |
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This study is also known as a longitudinal or incidence study design. |
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group of people who are either of the same age or share some other common characteristics |
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