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Epi - lec 5
Epi
12
Biology
Undergraduate 3
09/25/2012

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Term
for a factor to be associated with disease, it must have what relation between exposed and non-exposed individuals
Definition
it must be different among the exposed and non-exposed individuals
Term
mean is the measure of what for which kind of data?
- it doesn't tell us what?
- problem
Definition
central tendency for continuous data
- doesn't tell us about how values are distributed
- highly influenced by extreme values
Term
Central limit theorem
-results in
-basis for which test?
Definition
take a large sample of observations and calculate the mean of the values, and repeat over and over again.
wind up with:
- normal distribution***
- variance (s^2) which describes the variability of the sampled means in all directions
- a mean (ยต)
- standard deviations
*basis of z-test
Term
limitations of Central limit theorem
Definition
large sample size required
need to know standard deviation of population
Term
standard error or mean formula
Definition
SE = s/ (n^1/2)
Term
compare t-distriubtion to a normal distribution
- when do we have to use t-dist?
Definition
t distribution is shorter and wider than normal.
can't have normal distribution when use samples.
Term
what two things could we be testing for when we use a t-test?
Definition
test if single mean significantly different from zero
or
test if two means are significantly different from one another
Term
compare proportions and ratios
Definition
proportions is a fraction measure where numerator is included in denominator (0.5, 1/2, 50%)
ratios is a fraction measure where the numerator is NOT included in the denominator (A to B, A:B)
Term
when is X^2 (chi-square) test used?
Definition
when there are proportions or ratios since they can't be negative (so can't use t-distirubtion)
Term
p-value
Definition
the probability that the observed difference occurred due to chance or sampling variation. the probability that the test statistic would be larger or as large than calculated if the null hypothesis was true . probability of seeing test statistic calculated if no true difference between groups.
high p-value - likely taht difference was due to chance, should accept null.
low p-value < 0.05, only 5% chance association due to chance, so we reject null and state there is a difference/ association
Term
null hypoth
Definition
no difference between groups or association between exposure/disease
Term
equation for confidence interval
Definition
confidence = 1- alpha
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