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Enzymes of Glycolysis
The enzyme order of Glycolysis
22
Microbiology
Undergraduate 2
02/26/2014

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Cards

Term
What is the first enzyme used in Glycolysis?
Definition
Hexokinase
Term
What does Hexokinase do?
Definition
Takes an ATP and makes an ADP.  Adds a phosphate group to the 6th carbon of glucose, creating Glucose 6-phosphate
Term
What is the second enzyme in Glycolysis?
Definition
Phosphoglucose Isomerase
Term
What does phosphoglucose isomerase do?
Definition
Re-arranges molecules from the 1st and 2nd carbon groups, creating Fructose 6-phosphate
Term
What is the third enzyme in Gycolysis?
Definition
Phosphofructokinase
Term
What does phosphofructosekinase do?
Definition
Takes an ATP and makes an ADP.  Adds a phosphate group to the first carbon group creating Fructose 1,6-biphosphate.
Term
What is the fourth enzyme in Glycolysis?
Definition
Aldolase
Term
What does Aldolase do?
Definition
Splits the fructose 1,6 biphosphate into 2 compounds.  Dihydroxyacetone Phosphate and Glycereldahyde 3-phosphate.
Term
What is the fifth enzyme in Glycolysis?
Definition
Triose Phosphate Isomerase
Term
What does Triose Phosphate Isomerase do?
Definition
Rearranges molecules in Dihydroxyacetone Phosphate into Glyceraldehyde 3-phosphate
Term
What is the 6th enzyme in Glycolysis?
Definition
Glyceraldehyde 3-phosphate dehydrogenase
Term
What does Glyceraldehyde 3-phosphate dehydrogenase do?
Definition
Takes a Phosphate group and an NAD to reduce the NAD to NADH taking 1 hydrogen and convert the Glyceraldehyde 3-phosphate to 1,3 biphosphoglycerate, adding a phosphate group where the hydrogen was removed.
Term
What is the 7th enzyme in Glycolysis?
Definition
Phosphoglycerate Kinase
Term
What does Phosphoglycerate Kinase do?
Definition
Takes 2 ADP, makes 2 ATP.  Removes the 1 phosphate and makes 1,3 biphosphoglycerate into 3-phosphoglycerate.
Term
What is the 8th enzyme in Glycolysis?
Definition
Phosphoglycerate Mutase
Term
What does phosphoglycerate Mutase do?
Definition
Re-arranges the phosphate group from 3 to 2 making 3-phosphoglycerate into 2-phosphoglycerate
Term
What is the 9th enzyme in Glycolysis?
Definition
Enolase
Term
What does Enolase do?
Definition
Catalyzes a reaction that removes the -OH on C-3 and the -H on C-2 making water.  A double bond forms between C-2 and C-3.  Makes phosphoenolpyruvate.
Term
What is the 10th enzyme in Glycolysis?
Definition
Pyruvate Kinase
Term
What does Pyruvate Kinase do?
Definition
Takes 2 ADP and makes 2 ATP.  Changes Phosphoenolpyruvate to Pyruvate
Term
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Definition

Substrates

Glucose
Glucose-6-P
Fructose-6-P
Fructose-1,6-diP
Dihydroxyacetone-P
Glyceraldehyde-P
1,3-Biphosphoglycerate
3-Phosphoglycerate
2-Phosphoglycerate (to)
Phosphoenolpyruvate [PEP]
Pyruvate

Term
High Profile People Act Too Glamorous, Picture Posing Every Place
Definition

Enzymes

Hexokinase
Phosphoglucose isomerase
Phosphofructokinase (PFK)
Aldase A
Triose phosphate isomerase
Glyceraldehyde-3-phosphate dehydrogenase
Phosphoglycerate mutase
Enolase
Pyruvate kinase

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