Term
|
Definition
| Factor that may adversely affect health |
|
|
Term
|
Definition
| Probability that the hazard (factor) will adversely affect health |
|
|
Term
|
Definition
The alteration of a chemical/substance once it is in the body, mostly by the liver. May be (+) = hydrophilic, red-ox, hydrolysis. May be (-) = hydrophobic. Increases toxicity or Decreases toxicity (more polar, less fat soluble, easier to excrete).
Effects on kidneys/tubules |
|
|
Term
| Classifying environmental hazards |
|
Definition
|
|
Term
| Experimental investigative methods |
|
Definition
|
|
Term
| Scheme for identifying level of hazard and toxicity |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
Source --> External Exposure --> Internal Dose
(Source emissions --> Transport and transformation --> Accumulation in Enviro --> Human contact exposure --> Potential dose to body --> Internal dose --> Biologically effective dose --> Early expression --> Health effect) |
|
|
Term
|
Definition
Greater exposure: smaller particle size, aerodynamics, lipid soluble, higher breathing rate, greater tidal volume, lack respiratory protection
Less exposure: opposite of above
Example: Asbestos and small fibers from occupation (mining), inhaled, and gets into the gas exchange region. Causes mesothelioma. |
|
|
Term
|
Definition
Increase exposure: chemistry, physical form, presence of metals (Fe, Ca, Zn, Mg), fasting or full, children, liver excretion rate
Example: |
|
|
Term
|
Definition
Factors affecting exposure: Chemistry (solubility, molecular size, pH, temp, hydration)
Example: |
|
|
Term
|
Definition
|
|
