Term
enteropathogenic E. coli (EPEC)
site of action |
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Definition
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Term
enteropathogenic E. coli (EPEC)
diseases |
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Definition
infant diarrhea
watery diarrhea and vomitting
non-bloody stools |
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Term
enteropathogenic E. coli (EPEC)
pathogenesis |
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Definition
plasmid-mediated A/E histopathology
disruption of microvillus structure |
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Term
enterotoxigenis E. coli (ETEC)
site of action |
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Definition
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Term
enterotoxigenis E. coli (ETEC)
diseases |
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Definition
traveler's diarrhea
waterry diarrhea and vomitting
cramps
nausea
low-grade fever |
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Term
enterotoxigenis E. coli (ETEC)
pathogenesis |
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Definition
plasmid-mediated heat-stable and/or
heat labile enterotoxins
hypersecretion of fluids and electrolytes |
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Term
enterhemorrhagic E. coli (EHEC)
site of action |
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Definition
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Term
enterhemorrhagic E. coli (EHEC)
diseases |
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Definition
initial watery diarrhea follwed by
grossly bloody diarrhea
cramps
little or no fever
may progress to hemolytic uremic syndrome
(O157:H7) |
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Term
enterhemorrhagic E. coli (EHEC)
pathgenesis |
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Definition
mediated by shiga toxins (Stx-1, -2)
disrupts protein synthesis
A/E leisons |
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Term
enteroinvasive E. coli (EHEC)
site of action |
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Definition
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Term
enteroinvasive E. coli (EIEC)
diseases |
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Definition
fever
cramping
watery diarrhea
may progress to dysentery with scant
bloody stools |
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Term
enteroinvasive E. coli (EIEC)
pathogenesis |
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Definition
plasmid-mediated invasion and destruction of epithelial cells lining the gut |
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Term
enteroaggregative E. coli (EAEC)
site of action |
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Definition
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Term
enteroaggregative E. coli (EAEC)
diseases |
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Definition
Traveler's diarrhea
persistent watery diarrhea with vomitting
dehydration
low grade fever |
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Term
enteroaggregative E. coli (EAEC)
pathogenesis |
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Definition
plasmid-mediated aggregative adherence of rod
("stacked bricks":
shortened microvilli
mononuclesr infiltration
hemorrhage |
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Term
extraintestinal E. coli (UPEC)
site of action |
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Definition
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Term
extraintestinal E. coli (UPEC)
diseases |
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Definition
inflamation of the urogenital tract, bladder and kidneys |
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Term
extraintestinal E. coli (UPEC)
pathogenesis |
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Definition
produce specific adhesins (type 1 fimbriae)
P pili, AAF/I, AAF/II, Dr |
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Term
neontal E. coli (NMEC)
site of action |
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Definition
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Term
neontal E. coli (NMEC)
disease |
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Definition
meningitis
majority of CNS infections in infants <1 mth
often present in mother's and neonates' gastrointestinal tract |
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Term
neontal E. coli (NMEC)
pathogenesis |
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Definition
most strains produce the K1 capsular antigen |
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