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ENERGY HARVESTING PATHWAYS
BIO 311C
20
Biology
Undergraduate 1
05/12/2013

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Term
Catabolic Pathways
Definition
release chemical energy that can be used to make ATP
Term
Redox Reactions
Definition
chemical reactions involving the transfer of electrons form one reactant to another
Term
Oxidation
Definition

loss of electrons

 

OIL 

Term
Reduction
Definition

gain of electrons

 

RIG

Term
Oxidizing agent
Definition
gains electrons, is reduced
Term
Reducing Agent
Definition
loses electrons, is oxidized
Term
Aerobic Energy Harvesting
Definition
Cellular Respiration
Term
Stepwise Energy Harvesting
Definition

NAD+ -> NADH (stages 1-3) catalyzed by dehydrogenase

 

NADH -> NAD+ (stage 4)

Term
Electron Transport Chain
Definition

collection of molecules embedded in the inner membrane of the mitchondrion

 

electrons passed from NADH to O

 

electrons move from high energy to low energy through redox reactions

Term
Substrate-level Phosphorylation
Definition

enzyme transfers phosphate from a substrate molecule to ADP -> ATP

 

Enzyme? Kinase

 

Energy Source? Substrate + P

 

When? Glycolysis and Citric Acid Cycle

Term
ATP made by 2 mechanisms
Definition
Substrate-level phosphorylation and Chemiosmosis
Term
Chemiosmosis (oxidative phosphorylation)
Definition

enzyme adds P to ADP -> ATP, makes most ATP

 

Enzyme: ATP synthase

Energy source? protons diffusing down their gradient

 

When? Oxidative phosphorylation

Term
Glycolysis
Definition

1st stage of aerobic cellular respiration

 

Location: cytosol

Inputs: 1 glucose (6C), 4 ADP, 2 NAD+, 2 ATP

Outputs: 2 pyruvate (3C), 2 ATP, 2 NADH, 2 ADP

Term
Pyruvate Oxidation
Definition

2nd stage of aerobic cellular respiration

 

Location: mitochondrial matrix

Inputs: 2 pyruvate (3C), 2 CoA, 2 NAD+

Outputs: 2 Acetyl CoA, 2 CO2, 2 NADH

Term
Citric Acid Cycle
Definition

3rd stage of aerobic cellular respiration

 

Location: mitochondrial matrix

Inputs: 2 Acetyl CoA, 6 NAD+, 2 FAD, 2ADP

Outputs: 4 CO2, 2 CoA, 6 NADH, 2 FADH, 2 ATP

Term
Oxidative Phosphorylation
Definition

4th stage of aerobic cellular respiration

 

Location: inner mitochondrial membrane

Inputs: 10 NADH, 2 FADH2, O2, 28 ADP

Outputs: 10 NAD+, 2 FAD, H2O, 28 ATP

 

Term
Net ATP Yield of Cellular Respiration
Definition

Glycolysis: 2 ATP

Citric Acid Cycle: 2 ATP

Oxidative Phosphorylation: 28 ATP

Term
Fermentation
Definition

anaerobic energy harvesting

 

2 stages: glycolysis, NAD+ regeneration

Term
Fermentation Glycolysis
Definition
makes ATP, requires NAD+
Term
Regeneration of NAD+
Definition

oxidize NADH made in glycolysis by reducing pyruvate/derivative

 

necessary for glycolysis to continue

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