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Endocrinoly 1
Hormones, Glands, Phospholipase C etc.
27
Physiology
Undergraduate 1
03/14/2017

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Cards

Term
Sex hormones are fat soluble
Definition
True
Term
What are steroid hormones derived from
Definition
Cholesterol
Term
What will occur if noradrenaline acts on alpha- adrenergic receptors on vascular smooth muscle
Definition
vasoconstriction
Term
What type of receptor must noradrenaline act on to cause bronchdilation
Definition
beta-adrenergic receptors
Term
Through what medium are humoral signals sent?
Definition
Blood
Term
Endocrine glands release hormones in response to hormones released by other endocrine glands
Definition
True
Term
How to water soluble hormones act?
Definition
Via second messengers.
Term
Catecholamines can pass the lipid barrier?
Definition
False.
Term
cAMP
Definition
cyclic adenosine monophosphate
Term
Where are beta adrenergic receptors located?
Definition
Heart, arterioles of skeletal muscle, smooth muscles of bronchioles
Term
Name the enzyme that the G protein subunit of the b-Adren. receptor binds to on activation by adrenaline
Definition
adenylate cyclase
Term
Name the enzyme that convert ATP to cAMP
Definition
adenylate cyclase
Term
Name the enzyme in the cytosol that phophoralates proteins
Definition
Protein Kinase
Term
Name the membrane bound involved when an alpha-adrenergic receptor is stimulated by adrenaline
Definition
Phopholipase C
Term
Name the second messengers that are activated when adrenaline binds to an alpha-adrenergic receptor
Definition
IP3 - Inositol Triphosphate
DAG Diacylglcerol
Term
What causes Calcium ions to diffuse from the ER
Definition
IP3
It binds to its receptor on the ER membrane.
Term
What activates protein kinase in cells that have alpha-adren. receptors
Definition
Calcium calmodulin complex
Term
Name 2 hormones that bind to tyrosine kinase
Definition
growth factors
insulin
Term
When are insulin levels highest?
Definition
Just after a meal
Term
Glucagon binds to tyrosine kinase
Definition
False
Term
What step activates tyrosine kinase
Definition
Phosphorylation
Term
what is the net result of tyrosine kinase activation
Definition
Glucose uptake into the cell
Term
What type of receptor causes the eventual complexation of calcium and calmodulin
Definition
alpha adrenergic receptor
Term
With which receptor is the increase of cAMP associated?
Definition
beta-adrenergic
Term
Where are the majority of hormones deactivated
Definition
liver
Term
the effect of 2 hormones together being great than the sum alone
Definition
synergy
Term
Hormone enhances responsiveness of target to 2nd hormone
Definition
permissive
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