Shared Flashcard Set

Details

Endocrinology
Bio
40
Biology
Undergraduate 3
09/29/2012

Additional Biology Flashcards

 


 

Cards

Term
Anterior pituitary gland
Definition
hypophysiotropic neurons create hormones go through anterior part that affect endocrine cells and release into circulation
Term
Arrestin
Definition
shuts down function of receptors
prevents over stimulation
Term
Atrial nathriuretic peptide ANP
Definition
receptor is cGMP
secreted in heart
acts on kidney to increase sodium ion release in urine
heart is endocrine organ
Term
Catecholamine
Definition
can be both hormone and neurotransmitter
Term
Control of excessive hormonal stimulation
Definition
controlled mostly by short half lives of hormones
metabolized quickly
counter regulatory hormone = glucagon
Term
Down regulation
Definition
decrease # of active receptors in membrane
done by endocytosis
if needed again then resynthesized
Term
Eicosanoids
Definition
Prostaglandins, thromboxanes, prostacyclins, leukotriene, lipoxines
Term
G proteins
Definition
stay active as long as GTP is present until hormone leaves
Term
GHRH
Definition
growth hormone releasing hormone
regulates release of growth hormone
in pituitary
found in pancreas thyroid GI tract and kidney
Term
Glucagon
Definition
causes breakdown of liver glycogen to glucose 6-phosphate
can be dephosphoralated to glucose
Term
Inhibitory receptors would
Definition
inhibit G protein process
Term
Intracrine
Definition
acts inside the cell that created it, aka insulin
Term
Leukotrienes
Definition
allergic responses, branchio restriction
Term
Lipoxines
Definition
2 types, A= dialates, B= inhibits T-cell killers
Term
Median eminence
Definition
part in pituitary where blood flows and hormones are put into to go to circulation
Term
Parathyroid gland
Definition
controls release of PTH
PTH controls external [Ca+] and creates negative feedback which shuts down PTH release
Term
Parts of endocrine system
Definition
kidney heart gut hypothalamus
Term
Pituitary gland
Definition
2 parts- anterior (endocrine cells) posterior (produces hormones)
Term
Posterior pituitary
Definition
release oxytoxin, vasopressin, ADH
neurohypophysial cells
Term
Prostacyclins
Definition
causes blood vessel dialation
Term
Prostaglandins
Definition
Female repro, cardiovascular, creates pain
advil inhibits prostaglandins
Term
Regulation of hormones
Definition
Growth factors and ions regulate hormones
Term
Retenoids / Vitamin D
Definition
In nucleus, but can react in cytosol too
active usually in absence of hormone
Term
Second messengers
Definition
cAMP and cGMP
Term
Signal transporters
Definition
receptor, G protein, adenlase cyclase
Term
Steroids
Definition
can act on membrane receptors without entering cell
Term
Thromboxanes
Definition
blood platlets, blood clotting
Term
Up regulation
Definition
increase in # of active receptors when ther is a deficiency of hormone
Term
cGMP
Definition
similar to cAMP
has free forms in cytoplasm and attached forms
inactive at low con of Ca (cAMP is active at low conc of Ca)
[Ca+] influences which is used
Term
cell surface receptors
Definition
actin, thyroid sitmulating (all pepetides) adrenaline
Term
cytosolic receptors
Definition
lipid soluble
steroid/thyroid hormones
diffuse through membrane easily
Term
feedback loops
Definition
regulate responsiveness of receptor
Term
heat shock proteins
Definition
HSP assist in receptor and protein configuration
Blocks hormone response elements until hormone is on there and it is released
Term
hormone
Definition
regulates a function in target cell, does not initiate
Term
insulin receptor
Definition
2 monomers- alpha(outside cell) and beta(across membrane)
when insulin binds alphas form dimer
activates tyrosine kinase
Term
neuroendocrine cells
Definition
action potential releases neurohormones form synapse to blood
Term
non-lipid soluble hormones
Definition
not across membrane, use second messengers
Term
paracrine factor
Definition
hormones that can work without entering blood stream
Term
release of pituitary hormones
Definition
controlled by neuro-hormones in hypothalamus
Term
tropic hormones
Definition
hormones controlling other hormones
Supporting users have an ad free experience!