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Endocrine pathology
Terms and definitions
18
Veterinary Medicine
Undergraduate 3
04/19/2012

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Term
Acromegaly
Definition
Anterior pituitary gland produces too much GH
Term
Canine pituitary dwarfism
Definition
Failure to develop adenohypophysis and so lack of hormones from ant. and intermediate pituitary.
Most effects relate to lack of GH
Term
ACTH secreting adenoma
Definition
tumour of ACTH-secreting cells of ant. pituitary
Term
Central diabetes insipidus
Definition
Excessive thirst and severly diluted urine due to ADH deficiency. A decr. in fluid intake has no effect on urine conc
Term
Primary hyperparathyroidism
Definition
Excess PTH secretion from parathyroid gland
Term
Secondary hyperparathyroidism
Definition
Incr. PTH secretion from parathyroid gland due to decr. Ca++ levels due to other pathology
Term
Pseudohyperparathyroidism
Definition
Incr. PTH but not related to parathyroid gland
Term
Hypoparathyroidism
Definition
underfunction of parathyroid gland so decr. PTH and decr. Ca++
Term
Canine hypothyroidism
Definition
Autoimmune disease which destroys thyroid gland
Term
Goitre
Definition
Increased size of thyroid gland, can be nodular or diffuse.
Term
Canine thyroid neoplasia
Definition
Mostly carcinomas, i.e. malignant, and always non-functional
Term
Feline thyroid neoplasia
Definition
Hyperplastic or benign tumour of thyroid gland, functional so incr. T3/T4 and incr. metabolism
Term
Addison's disease
Definition
Hypoadrenocorticism - decr. adrenal cortex and so decr. GCC (cortisol) and aldosterone
Term
Cushing's syndrome
Definition
Hyperadrenocorticism - incr. levels of GCC (cortisol) in blood
Term
Senile nodular hyperplasia of adrenal cortex
Definition
incideental hyperplasia of adrenal cortex
Term
Phaeochromocytoma
Definition
Tumour of adrenal medulla, may secrete adrenaline
Term
Diabetes mellitus
Definition
Hyperglycaemia which results in glucosuria and PU/PD - due to failure to produce insulin (type I) or failure to respond to insulin (insulin resistant) (type II)
Term
Insulinoma
Definition
Most common pancreatic islet cell tumour, produces too much insulin resulting in hypoglycaemia
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