Term
What are some clinical signs of Hyperthyroidism |
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Definition
Weight loss
Palpitations
Vision changes Dry eyes
Tremor
Heat Intolerance |
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Term
How do you screen for Hyperthyroidism |
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Definition
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Term
How can you differentiate primary and secondary hyperthyroidism |
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Definition
Primary: High T4, low TSH
Secondary: High T4, High TSH |
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Term
What type of subclinical Hyperthyroid patient should be treated? |
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Definition
Older patient with persistance >6mths |
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Term
When should you get a 123 Isotope, Ultrasound, Fine Needle Aspiration? |
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Definition
123: Any Hyperthyroid
Ultrsound: Nodule on PE, other Imaging
Fine Needle: Euthyroid w/ >1cm nodule |
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Term
What are the phases of thyroiditis and when is it typically seen? |
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Definition
Thyrotoxic->Hypothyroid->Euthyroid Recovery
Post viral or Post-Partum |
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Term
What is the treatment for Thyroiditis? |
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Definition
B-block to protect heart
NSAIDs for pain
Yearly Thyroid Screening |
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Term
How do you differentiate Grave's from Thyroiditis? |
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Definition
Thyroiditis will show low uptake on 123 isotope |
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Term
How do you treat Grave's disease |
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Definition
131 Isotope
PTU or Methimazole
Maybe Surgery |
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Term
When is 131 Iodine Isotope contradicated and what precautions should patients take with this treatment? |
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Definition
Contra: Pregnant, Breast Feeding
Precaution: Prevent exposure to saliva, sweat, milk, urine, feces to other people for 3-4 days |
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Term
Why is Methimazole the prefered medical treatment of Hyperthyroid and when would PTU be preferred? |
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Definition
Better Taste, Less Hepatotoxicity, Once daily dose
PTU preferred in first trimester bc Meth can casue esophogeal and choanal atresia as well as Aplasia cutis |
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Term
What are the side effects of PTU or Methimazole? |
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Definition
Rash
Hepatotoxicity(PTU Black Box)
Agranulocytosis
ANCA Vasculitis |
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Term
What is the cause and treatment of Grave's related eye disease |
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Definition
Antibodies inflame the extraocular muscles
Treatment: Treat Hyperthyroid, refer to Opthalmologist(steroids, surgery, radiation) |
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Term
What is the treatment for Hyperfunctioning thyroid nodules |
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Definition
Radioactive Iodine or
Thyroidectomy |
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Term
How would you treat a Thyroid Storm |
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Definition
B-block
Anti-thyroids
Steroids
Iodine(Buys Time)
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