Term
| What is a craniopharyngioma? |
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Definition
cystic neoplasm arising from remnants of Rathke's pouch, mostly seen in a suprasellar location, in the hypothalamus
cysts contain a cholesterol-rich, thick brownish yellow fluid that has been compared to "machinery oil" |
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Term
| What is the most frequent cause of a hyperfunctioning gland? |
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Definition
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Term
| What are the signs/symptoms of a craniopharyngioma? |
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Definition
| increased intracranial pressure due to hydrocephalus, optic nerve encroachment, endocrine dysfxn |
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Term
| What is pituitary apoplexy? |
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Definition
| acute hemorrhage into an adenoma associated w/clinical evidence of a rapidly enlarging mass |
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Term
| How do you treat a prolactinoma? |
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Definition
| bromocriptine, a dompaine receptor agonist |
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Term
| What is Nelson's syndrome? |
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Definition
When Cushing's is treated by removal of adrenal, which removes inhibition on pituitary, so it secretes ACTH
(creates a mass lesion of pituitary) |
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Term
| How much of the pituitary parenchyma needs to be lost to cause hypopituitarism? |
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Definition
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Term
| What is the most common form of hypopituitarism? |
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Definition
| Sheehan's syndrome (postpartum necrosis) |
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Term
| What causes Sheehan's syndrome? |
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Definition
| pituitary enlarges during pregnancy and is relatively anoxic so if there is hypotension, the ant pituitary is vulnerable to ischemic necrosis |
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Term
| What is primary empty sella syndrome? |
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Definition
defect in diaphragma sellae lets fluid in so pituitary is compressed
mos tpatients are obese women w/a hx of multiple pregnanices
can get visual field defects and hyperprolactinemia |
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Term
| What is secondary empty sella? |
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Definition
| a mass, such as pituitary adenoma, enlarges the sella but then is removed by surgery or radiation |
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Term
| What are the clinical manifestations of SIADH? |
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Definition
hyponatremia
cerebral edema
neurologic dysfxn |
|
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Term
|
Definition
Wermer's Syndrome
Parathyroid
Pituitary
Pancreatic islet cells |
|
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Term
|
Definition
Sipple's Syndrome
medullary carcinoma of the thyroid
pheochromocytoma
hyperPTH |
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Term
|
Definition
Mucosal Neuroma Syndrome
multiple mucosal neuromas
medullary carcinoma of the thyroid
pheochromocytoma
often associated w/marfanoid habitus |
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