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Ventricular tachycardia has __ complex QRS. |
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Supraventricular tachycardia has __ complex QRS. |
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Non-drug option for treatment of Supraventricular Tachycardia (SVT): |
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Vagal maneuvers: hold breath, valsalva maneuver Carotid massage |
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SVT treatment options when vagal maneuveres do not work: |
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- Short term control: 6 mg IV Adenosine - Calcium Channel Blockers: Verapmil, Diltiazem - Beta Blokcers (slower than CCBs): Esmolol, Metroprolol Tartrate |
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With the treatment of Atrial fibrillation and atrial flutter, the goal is to control ___ __ and prevent __ __. |
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- ventricular rate - emoblic complications |
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Treatment options for Atrial Flutter and Atrial Fibrillation: |
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- Calcium channel blockers - Digoxin - Amiodarone
may have to use electrical cardioversion to restore sinus rhythm - Beta blockers |
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Wide complex tachycardia, aka __ __, in a stable patient should be treated with __ ___, __, or ___. __ should be used in patients with heart failure or structural heart disease. |
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- Ventricular tachycardia (b/c wide complex) - IV procainamide, propafenone, or flecainide - Amiodarone |
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Unstable wide complex VT should be treated with: |
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- Adenosine- to test be careful though - Immediate cardioversion |
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Common presenting symptoms of paroxysmal supraventricular tachycardia from most common to least common: |
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1. Palpitations 2. Dizziness 3. Shortness of Breath 4. Syncope 5. Chest pain 6. Fatigue 7 Diaphoresis 8. Nausea |
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- heart rate greater than 100 bpm - p waves similar to sinus rhythm |
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Sinus Node Reentrant Tachycardia: |
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- p waves similar to sinus rhythm - abrupt onset and offset |
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- Heart rate 120-250 bpm - P wave morphology different than sinus rhythm - Long RP interval - Tachycardia not terminated by AV block |
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Multifocal Atrial Tachycardia on EKG: |
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- Heart rate 100-200 bpm - 3 or more different P wave morphologies |
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- Heart rate 200-300 bpm - AV conduction 2:1 or 4:1 |
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Atrial Fibrillation on EKG: |
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- irregularly irregular rhythm - lack of discernable P waves |
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AV Nodal Reentrant Tachycardia: |
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- Heart rate 150-200 bpm - P wave either within the QRS or shortly after - Short RP interval in typical AVNRT, long RP interval in atypcial AVNRT |
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AV Reentrant Tachycardia on EKG: |
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- Heart rate 150-250 bpm - Narrow QRS in orthodromic conduction - Wide QRS in antidromic conduction - Dx excluded by AV block during SVT - P wave after QRS |
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How do you exclude dx of AV Reentrant Tachycardia: |
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- if there is an AV block during SVT then it is not AV reentrant tachycardia |
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List the different types of Supraventricular Tachycardias (SVTs): |
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- Sinus tachycardia - Inappropriate sinus tachycardia - Sinus node reentrant tachycardia - Atrial Tachycardia - Multifocal Atrial Tachycardia - Atrial Flutter - Atrial Fibrillation - AV Nodal Reentrant Tachycardia - AV Reentrant Tachycardia |
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Paroxysmal SVT can lead to: |
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- Heart Failure - Pulmonary Edema - Myocardial Ischemia - Myocardial Infarction
Chronic SVT can cause cardiomyopathy |
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- target end organ damage - systolic > 220 OR - diastolic > 125 |
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- greater than 180/110 - symptoms are NOT progressive and there is not end organ damage |
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Malignant hypertension is usually associated with __ __ and is characterized by ___ and ___ due to __ in ___. |
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- renal disease - hemolysis and thrombocytopenia - necrosis in arterioles |
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End Organ Damage due to HTNsive emergency, from most common to least common: |
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1. Cerebral Infarction 2. Hypertensive Encephalopathy 3. Acute Heart Failure Syndrome 4. Acute Coronary Syndrome 5. Intracerebral/Subdural Bleed 6. Aortic Dissection |
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Under normal circumstances, with an increase in blood pressure, the cerebral arterioles __ and cerebral blood flow stays the same. But during HTNsive emergencies, the elevated BP overwhelms autoregulation causing ___ leakage across capillaries and continued arteriole damage. This leads to __, the sine qua non of malignant HTN. The end result is __ __. |
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- constrict - transudate - PAPILLEDMA- sin quo non - hypertensive encephalopathy |
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Signs of HTNsive encephalopathy: |
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- Headaches - Irritability - Confusion - Somnolence |
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With HTNsive emergencies the heart is experiencing an increased ___ which leads to increased oxygen demand and __, this eventually can cause __ __, __ __, or __. |
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- workload - ischemia - pulmonary edema - myocardial ischmia - myocardial infarction |
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With HTNsive emergencies the renal system undergoes ___ and __ __, and an overall impairment of the autoregulation. this can manifest itself as: |
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- arteriosclerosis and fibrinoid necrosis - worsening renal function - hematuria - RBC cast formation - proteinuria |
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- Papilledema (optic disc swelling) - Cotton whool spots - Hemorrhages - Macular star |
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- more common in African Americans - males at greater risk for HTNsive emergencies than females - most commonly in middle aged (40s-50s) |
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Explain Cushing's Reflex: |
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brain hemorrhage> space occupying lesion in the brain> pushes against the brain> decreased blood flow to the brain> ischemia to the brain tells body that brain isn't getting enough blood> increased pressure> increased bleeding etc. etc. |
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Work-up in pt with HTNsive emergency: |
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- CBC - Chemistry - UA - Pregnancy test - CXR, Head CT, Chest CT, aortic angiogram - EKG, cardiac enzymes |
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In a HTNsive emergency, the blood pressure should be lowerd by __ of the mean arterial pressure. |
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2 main classes of drugs to lower blood pressure in the ER; |
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- Vasodilators - Anti-Adrenergic Agents |
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4 vasodilators that are good to use in ER to lower bp with HTNsive emergencies: |
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- Nitroprusside - Nicardipine - Enalapril - Fenoldopam
(Don't use nitroglycerin or hydralizine in these cases b/c bp will drop too rapidly) |
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Nitroprusside is a vasodilator that can be given in HTNsive emergencies. Give the dosage, onset, and adverse effects: |
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Dosage: 0.25-10mcg/kg/min Instant onset 1-2 minutes Adverse effects: cyanide poisoning |
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Nicardipine is a vasodilator that can be used in HTNsive emergencies. Give the dosage, onset, and adverse effects: |
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Dosage: 5-15 mg/hr Onset/duration: 5-10 min/1-4 hours Side effects: Tachycardia, flushing AVOID WITH HEART FAILURE |
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Enalapril is an ACE-I vasodilator used in HTNsive emergencies. Dosage, onset/duration, side effects: |
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dosage: 10-40 mg IM, 1.25-5 mgIVq6hours onset: 20-30 min/6 hours SE: hypotension, renal failure, hyperkalemia |
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Fenoldopam is a ___ ___ vasodilator used in HTNsive emergencies. Dosage, onset/duration, side effects: |
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- dopamine 1 agonist - dosage: 0.1-0.3 mcg/kg/min - onset/duation: 20-30 min/6 hours - SE: flushing, headache, tachycardia |
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Name 3 adrenergic antagonists that can be used with HTNsive emergencies: |
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- Labetalol (alpha1, beta 1 and 2 blocker), some sympathomimetic effect - Esmolol- beta-1 selective blocker - Phentolamine- alpha 1 blocker |
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Adverse effects of Labetalol: |
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- heart block - orthostatic hypotension - avoid in heart failure and asthma |
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- hypotension - avoid with heart failure and asthma
very short acting |
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- tachycardia - flushing - headache
can use this one in asthma b/c only block alpha 1 receptors, no effect on beta receptors |
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Oral drugs that can be used in HTNsive emergencies: |
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- Captopril- ACE-I - Clonidine- central acting alpha 2 agonist - Labetalol |
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hypotension in high renin states
benefit: very short acting |
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- dry mouth - sedation - bradycardia |
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- heart failure - heart block - bronchospasm |
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How to rapidly reduce bp with acute myocardial ischemia? |
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- IV nitroglycerin, beta blockers, ACE-inhibitors |
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How to rapidly reduce bp in pt with CHF with pumonary edema: |
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- IV nitroglycerin, furosemide, morphine |
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How to rapidly reduce bp in acute aortic dissection: |
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- IV nitroprusside + beta blocker OR - IV trimethaphan + beta blocker |
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How to rapidly decrease bp with hypertensive encephalopathy or SA hemorrhage: |
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- IV nitroprusside, labetalol or nimodipine |
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How to rapidly reduce bp with MAO tyramine interactions with acute HTN: |
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