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Embryology
Embryology
25
Medical
Undergraduate 1
03/20/2013

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Term
What is the zona pellucida?
Definition
The clear membrane surrounding the ovum which the sperm has to cross for fertilisation. Then provides the capsule for the division of zygote cells.
Term
What is the name of the diploid cell with in the zona pellucida post fertilisation?
Definition
Zygote
Term
After mitotic divisions and compacting of the blastomeres, what structure is formed at 16 cells?
Definition
Morula
Term
Why is the compacting of blastomere cells within the morula important?
Definition
Allows efficient cell to cell signalling and communication
Term
In a morula, what do inner cells become?
Definition
Tissue of the embryo- embryoblast
Term
In a morula what do outer cells become?
Definition
Placenta- trophoblast
Term
DAY 5 At which point does a morula become a blastocyst?
Definition
The formation of a blastocoele from the production of fluid by the embryoblast cells before they become uni-polar within the blastcyst
Term
DAY 6: At which point is the zona pellucida in development?
Definition
Implantation of the Blastocyst (embryo pole first) allowing trophoblastic cells to come in contact with the uterus
Term
What is decidualisation?
Definition
The changes made in the uterine lining in order to allow for the trophoblastic cells to invade.
Term
WEEK 2: When the trophoblastic cells begin to invade the uterine lining, what are the 2 layers that initially develop?
Definition
Outer- syncitiotrophoblast
Inner- cytotrophoblast
Term
What are the first two layers that the embryoblast develop into?
Definition
Epiblast and hypoblast, forming a bi-laminar embryonic disc.
Term
In what week does the amniotic cavity begin to develop and how?
Definition
Week 2, differentiation of embryoblasts into amnioblasts which secrete fluid creating the cavity.
Term
How is the exocoelomic cavity formed?
Definition
Hypoblastic cells produce a membrane surrounding blastocoele
Term
What happens in the lacuna stage of embryonic development?
Definition
Syncitiotrophoblast cells continue to multiply forming the syncitium. Vaculoes begin to appear, which merge, increase in size and become lacuni. These eventually establish the maternal-utero circulation.
Term
Human chorionic gonadotrophin is used for and formed by what?
Definition
Used for pregnancy testing and produced by placental cells, 2 weeks after fertilisation.
Term
What cavity surrounds the embryoblast cells sepertaing them from the trophoblastic cells other than the connecting stalk at the END OF WEEK 2?
Definition
Chorionic Cavity
Term
What occurs to the embryoblast at the beginning of week 3 in gastrolation?
Definition
Becomes a tri-laminar disc from a bi-laminar disc. Epiblast forms the ectoderm, endoderm and the mesoderm. Hypoblast forms the extra embryonic ectoderm.
Term
What forms in morphogenesis?
Definition
A primitive streak and primitive node
Term
What is a primitive streak?
Definition
Central to the epiblast resulting from cells 'diving down' through to other layers.
Term
What is the primitive node?
Definition
Circular cephalic end of the primitive streak
Term
What is diffrerent about the cell layers at the bucco-pharyngeal membrane and cloacal membrane?
Definition
There is no mesoderm layer, tightly adherent.
Term
What does the ectoderm layer form?
Definition
Epidermis, central/peripheral nervous system and retina of the eye.
Term
What does the endoderm become?
Definition
Epithelial layers of the resp and GI tract, glandular cells (e.g. liver/pancreas.
Term
What does mesoderm form?
Definition
Connective tissue, muscle, heart, vascular system and reproductive organs. (all in between endoderm and ectoderm)
Term
What is the notochord?
Definition
Cells passing into the primitive streak and remaining in midline through endoderm. Signalling centre controlling development of midline structures.
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