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Embryology
Gastrulation Quiz 1
35
Medical
Professional
08/23/2012

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Term
Prechordal Plate
Definition
Minor contribution to head
brain functioning
increase function or size can result in siamese twins
Term
"The Organizer" (gastrulation)
Definition
Group of cells responsible for formation of "body plan" (organizes pattern of gastrulation)
Term
Duplicated organizer function results in...
Definition
craniopagus parasiticus (duplicated head, rotated 90 degrees)
Term
Reduced function of the notochord results in...
Definition
defective midline structures (holoprosencephaly)
Caused by disruption of Sonic hedgehog
Term
Somites
Definition
paraxial mesodermal balls
contribute to skin, muscle, and bone
(sclerotomes --> axial skeleton)
(dermomyotome__>dermatome-->dermis)
(dermomyotome-->myotome-->skeletal muscle)
Term
Lateral plate mesoderm forms...
Definition
Splanchnic and somatic mesoderm
Term
Inadequate production of trunk mesoderm results in...
Definition
Sirenomelia (mermaid syndrome)
Not enough mesoderm formed, due to genes Tsg and BMP7
Term
Gastroschisis
Definition
Digestive organs located outside of body due to inadequate body folding
Term
Somatic mesoderm
Definition
adjacent to trophoblast: these two tissues together are called the chorionic membrane
Term
Splanchnic mesoderm
Definition
adjacent to Heuser's membrane
Term
Functions of Placenta (name 3)
Definition
1. Exchange of oxygen, nutrients, and waste
2. Modulation of maternal immune system
3. Produces hormones:
A. Progesterone and estrogen
B. chorionic somatomammotropin (human placental lactogen): growth, lactation, and lipid metal;
C. human placental growth hormone, which regulates placental growth and maternal glucose levels
Term
Gametogenesis
Definition
biological process by which diploid or haploid precursor cells undergo cell division and differentiation to form mature haploid gametes
Term

What causes

Craniophagus Parasiticus

Definition

Increased activity or duplication

of ORGANIZER function

Term

What causes

Dicephalys?

Definition

Increased activity or increased number of

Goosecoid gene transcription factor

in the prechordal plate

 

Term

What causes

midline defects

such

Cyclopia and Holoprosencephaly

Definition

Decreased activity of notochord

usually due to disruption of

Sonic Hedgehog signaling

Term
mesdermal derivatives from cranial to caudal
Definition
prechordal plate (head and brain) - paraxial of head (head muscle and some bone) - lateral plate of head (cardiac mesoderm) - paraxial trunk(somites) - intermediate trunk(urogenital) - lateral trunk(somatic and splanchic) - tail bud (posterior spinal cord and tail)
Term
what happens with overproduction of goosecoid transcription factor
Definition
human dicephalus (prechordal plate overproduction, siamese twins)
Term
what germ layer forms the neural tube.
Definition
ectoderm
Term
what process translocates the heart, pericardial cavity and septum transversum.
Definition
head fold
Term
what forms from the septum transversum.
Definition
diaphragm (pleuralperitoneum folds and fuses with septum transversum, a muscle ingrowth develops inside)
Term
T/F plueralpericardial folds fuse together to form both the pericardial and pleural cavities.
Definition
True
Term
what forms when the cytotrophoblast extends up towards synctiatrophoblast
Definition
vili of placenta
Term
Dermomyotome makes....
Definition

the dermatome (dermis)

&

the myotome (skeletal muscle)

Term
Sclerotome develope into....
Definition
the axial skeleton
Term

The axial skeleton

the dermis

skeletan muscle

 

are all made from what mesodermal subdivision

Definition
somites
Term

what two layers are made from the

lateral plate mesoderm?

Definition

Somatic mesoderm layer

Splanchnic mesoderm layer

Term

What causes

Sirenomelia?

Definition

defective production of

trunk measoderm.

 

mutation in the TSG and BMP7 genes

Term
what is the epiblast called after gastrularion and after neurulation?
Definition

after gastrulation: ectoderm

after neurulation: epidermis

Term
Defect in positioning of body folds (pinching off is too dorsal)
Definition
Gastroschisis
Term
What produces the villi of the placenta?
Definition
The trophoblast
Term
what is the main contributor for the placenta?
Definition
Decidua basalis
Term
what is the chorion?
Definition
membrane formed by extraembryonic mesoderm and the two layers of trophoblast. it surrounds the embryo
Term
what does hCG do
Definition
maintains the corpus luteum
Term
what maintains pregnancy after 1st trimester?
Definition
Progesterone and estrogens
Term
what regulates placental growth and maternal glucose levels
Definition
human plancetal growth hormone
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