Term
| What are the 3 factors that cause birth defects |
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Definition
| environmental, gentic factors, combination of both |
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Term
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Definition
| absence of an organ or body region resulting from failure of development of its precursor. |
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Term
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Definition
| absence of an organ or body region resulting from the absence of its precursor |
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Term
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Definition
| anomalies in form, shape, or position of an organ or body region caused by an extrinsic mechanical factor. |
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Term
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Definition
| defects in development of an organ or body region resulting from a disruption of an originally normal developmental process of its precursor |
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Term
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Definition
| defects in development of an organ or body region resulting from an abnormality in the developmental potential of its precursor. |
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Term
| Numerical chromosomal abnormalities |
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Definition
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Term
| What are the symptoms of Trisomy 21 and what is the name? |
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Definition
| mental retardation, congenital heart defects, microcephaly, microphtalmia, colobomata, cataracts, glaucoma, umbilical hernia and duodenal atresia. |
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Term
| What are the signs and symptoms of Edward's Syndrome? |
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Definition
| much less common than trixomy 21. usually die son after birth. Flexed digits, mental retardation, congentical heart defects, prominent occiput, low set ears, flexed digits, and rocker-bottom feet. |
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Term
| What are the signs and symptoms of Trisomy 13? |
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Definition
| Patau syndrome. mental retardation, microphthalmia, congenital heart defects, deafness, colobomata, and left lip and cleft palate. |
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Term
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Definition
| XXY. characterized by male hypogonadism, sterility, and gynocomastia. |
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Term
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Definition
| XO, female hypogonadism. Infantile genitalia, hypoplastic ovaries, congenital heart defects, webbed neck; lymphedema of extremities. most common cause of primary amenorrhea. |
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Term
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Definition
| characterized by presence of two sex chromatin bodies. normal in habitus and are usally fertile; 20% mildly retarded. |
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Term
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Definition
| results from deletion of teh short arm of chromosome 5. Cat like cry, mental retardation, microcephaly. Low birth weight, microcephaly, feeding difficulties, language difficulties, hypotonia. |
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Term
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Definition
| associated with deletion of bandq12 on crhomosome 15(. hypogonadism, hyperphagia, mental retardation. |
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Term
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Definition
| associated with deletion of band q12 on chromosome 15 (found in mother). mental retardation, seizures, dystaxia. |
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Term
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Definition
| deletion of band q11 on chromosom 22. Absence of the thymus and parathyroid gl. and T-cell immunodeficiency. |
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Term
| Achondroplasia and polydactyly are defects of what? |
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Definition
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Term
| What can neural tube defects result in? |
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Definition
| Spina bifida, encephalocele, myeloschisis, anencephaly. elvated alpha-fetoprotein levels in maternal serum and amniotic fluid. |
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Term
| Rubella Virus effects on developing embryo or fetus |
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Definition
| Effects of the developing embryo or fetus; heart defects, cataracts deafness mental retardation microcephaly blindness. |
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Term
| What does thalidomide do? |
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Definition
| Harms baby, and is antinauseant |
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Term
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Definition
| antineoplastic agents, and a folic acid antagonist. |
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Term
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Definition
| derivative of amniopterin is a folic acid antagonist resulting in skeletal anomalies. |
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Term
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Definition
| For treatment of manic-depressive disorder. congenital anomalies of the heart and great vessels. |
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Term
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Definition
| cystic acne. craniofacial anomalies, spina bifida cystica, cardiovascular defects. |
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Term
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Definition
| crosses placental barrier, anticoagulatn and a vit. K antagonist that is used to treat thromboembolic disease. mental retardation, microcephaly, optic atrophy |
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Term
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Definition
| antianxiety agent. use in first trimester of pregnancy causes craniofacial deformities. |
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Term
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Definition
| cause stained teeth and hypoplasia enamel and reduced growth of long bones. |
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Term
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Definition
| causes sensorineural deafness. |
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Term
| Symptoms of Fetal-Alcohol Syndrome |
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Definition
| mental retardation, microcephaly, craniofacial abnormalities, limb deformities, cardiovascular defects. |
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Term
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Definition
| Cause intrauterine growth retardation, premature delivery, low birth weight, decreases uterine blood flow and diminished capacity of the blood to transport oxygen to fetal tissue. |
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Term
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Definition
| not known to be a human teratogen. |
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Term
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Definition
| are teratogenic in pregnant woman. may cause VACTERL syndrome. |
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Term
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Definition
| may cause mental retardation, microcephaly, cerebral infarction, urogenital defect. |
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Term
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Definition
| cause structural chromosomal damage. congenital anomalies. |
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Term
| What are 3 conditions that result from failure of the neural crest cell migration? |
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Definition
| Digeorge syndrome, Cardia malformations, Hirschsprung disease. |
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Term
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Definition
| nongenetic form of T-cell deficiency. results from failure of the neural crest cells to populate pharyngeal pouches 3 and 4 and give rise to the thymus and parathyroid glands. congenital hypothyroidism and facial and cardiac abnormalities. |
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Term
| What is Hirschsprung Disease |
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Definition
| congenital aganglionic megacolon. |
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