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Embryology Ear and Eye
Embryology Ear and Eye
41
Science
Undergraduate 4
03/20/2009

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Term
Internal Ear
Definition
Develops in week 4 from a thickening of the surface ectoderm called the otic placode.
Term
Otic Vesicle
Definition
divides into utricular and saccular portions.
Term
Utricular function
Definition
contains the sensory hair cells and otoliths of the macula utriculi. It responds to linear acceleration and force of gravity.
Term
Semicircular ducts
Definition
contain the sensory hair cells of the cristae ampullares. respond to angular acceleration.
Term
Vestibular ganglion
Definition
CN VIII which lies at the base of the internal auditory meatus.
Term
Endolymphatic duct and sac
Definition
membranous canal connecting with the saccule and utricle and terminating in a blind dilation beneath the dura. absorbs endolymph.
Term
what portions rise from the utricular otic vesicle?
Definition
Utricle, Semiccircular Ducts, Vestibular ganglion, endolymphatic duct and sac
Term
What structures arise from the saccular portion of the otic vesicles?
Definition
Saccule, Cochlear Duct, spiral Ganglion
Term
Membranous and Bony Labyrinth
Definition
Membranous labyrinth, consists of all structures derived from otic vesicle.
Term
Malleus
Definition
develops from cartilage of pharyngeal arch 1. Attached to tympanic membrane 2. Moved by the tympani muscle, which is innervated by CN V-3.
Term
What nerve innervates the tympani muscle?
Definition
CN V-3
Term
Incus
Definition
develops from the cartilage of pharyngeal arch 1. articulates with the malleus and stapes.
Term
Stapes
Definition
develops from the cartilage of pharyngeal arch 2. moved by the stapedius muscle, which is innervated by CN VII. attached to the oval window of the vestibule.
Term
Auditory tube and middle ear cavity
Definition
develops from the pharyngeal pouch 1.
Term
Tympanic Membrane
Definition
develops from pharyngeal membrane 1. separates the middle ear from the external auditory meatus of the external ear. CNV-3 CN IX.
Term
Auricle
Definition
develops from six auricular hillocks that surround pharyngeal groove 1. innervated CNV-3, CNVII, CN IX, and CNX, and cervical nerves C-2, and C-3
Term
Congenital Deafness
Definition
organ of corti may be damaged by exposure to rubella virus, especially during week 7 and week 8 of development.
Term
Malformation of the Auricles in chromosomal syndromes
Definition
seen in Down Syndrome, Patau syndrome, and edwards syndrome.
Term
Atresia of External Auditory Meatus
Definition
results from failure of the meatal to canalize; this is condition deafness and is usually associated with the first arch syndrome.
Term
Congenital Cholesteatoma
Definition
frequent cause of conduction deafness. benign tumor found in the tympanic cavity; is thought to develop from epidermoid thickenings of endodermal lining.
Term
What does the outer layer of the optic cup give rise to?
Definition
It gives rise to the pigment layer of the retina!
Term
What structure begins the formation of the eye?
Definition
Optic sulcus, evaginates from the wall of the diencephalon as the optic vesicle consisting of neuroectoderm.
Term
Intraretinal Space
Definition
separates the pigment layer of the retina from teh neural layer of the retina. becomes a potential space. common site of retinal detachment.
Term
Inner neural layer of the optic cup
Definition
gives rise to the neural layer of the retina. (rods and cones, bipolar cells, and ganglion cells)
Term
What virus can cause permanent damage to the developing ear resulting in congenital deafness?
Definition
Rubella Virus
Term
What sensory hair cells are located in the semicircular canal
Definition
cristae ampullares
Term
Iris
Definition
develops from the other portions of both the outer pigment layer. stroma develops from mesoderm continuous with choroid. contains pupillae muscle and sphincter pupillae muscle.
Term
What structure do the stroma develop from in the eye?
Definition
They develop from the mesoderm which is continuous with the choroid.
Term
Coloboma Iridis
Definition
cleft in iris caused by failure of choroid fissure to close in week 7 of development. may extend into the ci99liary body, retina, choroiidd, or optic nerve
Term
Persistent Iridopupillary Membrane
Definition
consists of strands of connective tissue that partially cover the pupil; seldom affects vision.
Term
Congenital Cataracts
Definition
are opacities of the lens, usually bilateral. common and may result from following: rubella virus infection, congenital syphilis, down syndrome, galactosemia
Term
what are the possible causes of congenital cataracts?
Definition
rubella virus infection, congenital syphilis, down syndrome, galactosemia.
Term
Congenital Glaucoma symptoms
Definition
photophobia, epiphora, blepharospasm
Term
What is the usual treatment of congenital glaucoma?
Definition
trabeculotomy
Term
Microphthalmia
Definition
small eye, usually associated with intrauterine infections from the TORCH group of Toxoplasma, Rubella virus, Cytomeggalovirus, and herpes simplex virus.
Term
Anopthalmia
Definition
absence of eye due to failure of the optic vesicle to form.
Term
Cyclopia
Definition
single orbit and one eye. due to failure of median cerebral structures to develop.
Term
Retinocele
Definition
herniation of retina into the sclera. rsults from failure of the choroid fissure to close.
Term
Retrolental fibroplasia
Definition
oxygen-induced retinopathy seen in premature infants.
Term
Papilledema
Definition
edema of optic disk due to increased intracranial pressure reflected into subarachnoid space.
Term
Retinitis Pigmentosa
Definition
hereditary degeneration and atrophy of retina. night blindness
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