Term
Menstrual age duration and user Fertilization age duration and user |
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Definition
Menstrual = 40 weeks, clinicians, obstetricians Fertilization = 38, embryolgists |
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Term
Menstrual age periods Fertilization periods |
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Definition
Menstrual = three equal trimesters Early development=first 2 weeks, Embyronic period=3-8weeks, Foetal period=9 weeks |
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Term
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Definition
Genetic/environmental factors (50% unknown, 25% multifactorial, 10% chromosomal, 8% monogenetic, 7% major environment) |
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Term
5 types of teratogens (environmental causes) |
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Definition
Infectious agents Physical agents Chemical agents Maternal disease Nutritional deficiencies |
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Term
Examples of: Infectious Physical Chemical Maternal Disease Nutritional deficiencies |
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Definition
Virus Radiation Pharmaceutical drugs Diabetes Obesity |
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Term
When are teratogens most likely to cause birth defects? |
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Definition
Week 5, (but also weeks 3-8) |
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Term
What do TORCH teratogens have in common? |
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Definition
All can cross the placenta |
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Term
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Definition
Toxoplasmosis Other Rubella Cytomegalovirus HSV (baby close to female sexual organ) |
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Term
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Definition
Shortened or absent limbs |
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Term
Foetal Alcohol Syndrome [FAS] relationships |
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Definition
Alcohol consumption and congenital defects Amount consumed and severity of birth defects |
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Term
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Definition
Small eye opening Smooth philtrum Thin upper lip Associated w/ growth retardation and intellectual disability |
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Term
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Definition
Germ cell w/ haploid chromosome complement (23 for humans) |
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Term
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Definition
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Term
Usual site of fertilization |
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Definition
Ampulla (bend in fallopian tube) |
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Term
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Definition
Sweep oocyte into uterine tube |
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Term
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Definition
Sperm undergo maturation process in female reproductive tract |
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Term
Ability of capacitated sperm |
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Definition
pass through corona radiata |
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Term
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Definition
Sperm bind to zona pellucida and acrosome enzymes break down zone pellucida |
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Term
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Definition
After fertilization, cell undergoes series of cell divisions. |
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Term
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Definition
Zygote does not grown, cells (blastomeres) get smaller |
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Term
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Definition
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Term
Inner masss = Outer cell mass = |
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Definition
Form embryo proper - Embryoblast Form placenta - Trophoblast |
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Term
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Definition
Morula develops fluid filled cavity and transforms into blastocyst. |
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Term
What happens to the blastocyst after 5-6 days |
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Definition
It enters the uterine cavity, hatches and shed the zona pellucida |
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Term
What does the zona pellucida prevent |
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Definition
Implantation into the uterus membrane |
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Term
Function of throphoblast cells at implantation |
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Definition
Merge w/ membrane of unterus, form continuous membrane and secrete immune suppressing hormones |
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Term
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Definition
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Term
What do cells differentiate into during week 2? |
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Definition
The epiblast or hypoblast. This creates a distinct layer between inner cell mass of the blastocyst |
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Term
How is full implantation achieved |
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Definition
A coagulation plug is formed in the uterus membrane. Maternal capillaries near the blastocyst will eventualy supply it. |
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Term
What does the blastocyst rely on for the first 2 weeks? |
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Definition
Diffusion from uterine glands |
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Term
How is pregnancy testing made possible? |
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Definition
Syncytiotrophoblast (outer syncitial [multinucleated mass of cytoplasm which is not separated into individual cells] layer of the trophoblast that actively invades the uterine wall forming the outermost foetal component of the placenta) secretes hCG hormone |
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Term
Abnormal implantation sites |
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Definition
Ampulla Fallopian tube Cervix |
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