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Embryology 1
n/a
32
Dentistry
Undergraduate 3
05/13/2015

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Term
Menstrual age duration and user
Fertilization age duration and user
Definition
Menstrual = 40 weeks, clinicians, obstetricians
Fertilization = 38, embryolgists
Term
Menstrual age periods
Fertilization periods
Definition
Menstrual = three equal trimesters
Early development=first 2 weeks, Embyronic period=3-8weeks, Foetal period=9 weeks
Term
Causes of birth defects
Definition
Genetic/environmental factors
(50% unknown, 25% multifactorial, 10% chromosomal, 8% monogenetic, 7% major environment)
Term
5 types of teratogens (environmental causes)
Definition
Infectious agents
Physical agents
Chemical agents
Maternal disease
Nutritional deficiencies
Term
Examples of:
Infectious
Physical
Chemical
Maternal Disease
Nutritional deficiencies
Definition
Virus
Radiation
Pharmaceutical drugs
Diabetes
Obesity
Term
When are teratogens most likely to cause birth defects?
Definition
Week 5, (but also weeks 3-8)
Term
What do TORCH teratogens have in common?
Definition
All can cross the placenta
Term
TORCH teratogens
Definition
Toxoplasmosis
Other
Rubella
Cytomegalovirus
HSV (baby close to female sexual organ)
Term
Effects of thalidomide
Definition
Shortened or absent limbs
Term
Foetal Alcohol Syndrome [FAS] relationships
Definition
Alcohol consumption and congenital defects
Amount consumed and severity of birth defects
Term
Characteristic of FAS
Definition
Small eye opening
Smooth philtrum
Thin upper lip
Associated w/ growth retardation and intellectual disability
Term
Gamete
Definition
Germ cell w/ haploid chromosome complement (23 for humans)
Term
Gametes fuse to make
Definition
Zygote
Term
Usual site of fertilization
Definition
Ampulla (bend in fallopian tube)
Term
Function of fimbrae
Definition
Sweep oocyte into uterine tube
Term
Capacitation
Definition
Sperm undergo maturation process in female reproductive tract
Term
Ability of capacitated sperm
Definition
pass through corona radiata
Term
Acrosome enzyme function
Definition
Sperm bind to zona pellucida and acrosome enzymes break down zone pellucida
Term
Cleavage ;)
Definition
After fertilization, cell undergoes series of cell divisions.
Term
Cleavage change in size
Definition
Zygote does not grown, cells (blastomeres) get smaller
Term
Morula stage
Definition
16-32 cells
Term
Inner masss =
Outer cell mass =
Definition
Form embryo proper - Embryoblast
Form placenta - Trophoblast
Term
Blastocyst formation
Definition
Morula develops fluid filled cavity and transforms into blastocyst.
Term
What happens to the blastocyst after 5-6 days
Definition
It enters the uterine cavity, hatches and shed the zona pellucida
Term
What does the zona pellucida prevent
Definition
Implantation into the uterus membrane
Term
Function of throphoblast cells at implantation
Definition
Merge w/ membrane of unterus, form continuous membrane and secrete immune suppressing hormones
Term
Week 2 =
Definition
Week of 2
Term
What do cells differentiate into during week 2?
Definition
The epiblast or hypoblast. This creates a distinct layer between inner cell mass of the blastocyst
Term
How is full implantation achieved
Definition
A coagulation plug is formed in the uterus membrane. Maternal capillaries near the blastocyst will eventualy supply it.
Term
What does the blastocyst rely on for the first 2 weeks?
Definition
Diffusion from uterine glands
Term
How is pregnancy testing made possible?
Definition
Syncytiotrophoblast (outer syncitial [multinucleated mass of cytoplasm which is not separated into individual cells] layer of the trophoblast that actively invades the uterine wall forming the outermost foetal component of the placenta) secretes hCG hormone
Term
Abnormal implantation sites
Definition
Ampulla
Fallopian tube
Cervix
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